KJC Korea
Journal Central

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Comparative blood analysis was carried out to investigate the change of blood constituent in TAE-EUM-IN group and control group. RBC, WBC, hemoglobin, hematocrit, total protein, triglyceride, phospholipid, total cholesterol, LDL-cholesterol, HDL-cholesterol, BUN, creatinine, ACTH, cortisol and prostaglandin E and F2α were measured. And the following results were obtained:1. In the change of blood cell, the value of hematocrit showed significant difference, while that of RBC, WBC and hemoglobin didn't. 2. In the change of protein, the value of total protein showed significant difference, but that of albnumin didn't. 3. In the change of lipid and cholesterol in serum, the value of triglyceride, phospholipid, total cholesterol and LDL-choleterol indicated significant difference, while that of HDL-cholesterol didn't. 4. The value of BUN in serum represented significant difference, but that of creatinine didn't. 5. The value of cortisol in plasma showed significant difference, but that of ACTH didn't. 6. The value of prostaglandin E and F2α in plasma showed significant difference. These results suggest that investigation on hormones and blood constituents enables objectification in differentiation of four types of physical constitution.

These studies were conducted about the effects of Ferric oxide in the aspect of the basic pharmacology through experimental animals with the investigation of its clinical effects on oriental medical literatures of Ferric oxide. The results were as follows:1. The analgenic effects induced by acetic acid were significant. 2. The anticonvulsive effects induced by ECT unit were significant. 3. The sedative effects in Rotor rod method were significant. 4. The number of platelets was increased but not significantly. 5. Prothrombin time was decreased significantly. 6. Fibrinogen was increased but not significantly. 7. The degree of concentration of FDP was decreased significantly. According to the above results, it is considered that Ferric oxide retains effectiveness on the treatment of cerebral stroke.

Knowing the reason for constitutional severe sweating of Tae-Eum-In, we have collected 20 person of Tae-Eum-In and 20 person of the others, and measured weight and circumference of neck, chest, abdomen and hip and cholinesterase, epinephrine and norepinephrine in blood. Except group of epinephrine among them, remarkable difference had been in the rest comparision, so it considered that be able to distinguish the characteristics of constitutions.

In order to investigate experimental effects of YangkyukSanwha-Tang, which is the typical prescription for diseased SOYANGIN, on diabetes rats, the observation and measurement was made on the content of volume of blood glucose, total cholesterol, triglyceride, phospholipid, total protein, electrolyte (K+, Na+) in serum, by dosing the cooked Y.S.T. to diabetic rats, induced by streptozotocin and following result was obtained. 1. The volume of blood glucose, in the diabetic rats, was decreased significantly, and remarkable decrease of blood glucose was shown in the Y.S.T. (12.5ml/kg) dosed group, after 4 weeks of experiment. 2. The volume of total cholesterol of blood serum was decreased notably, especially remarkable reduce of total cholesterol was shown in the Y.S. T. (12.5ml/kg) dosed group after a week. 3. The volume of triglyceride in the blood serum of diabetic rats, induced by the streptozotocin was decreased after 4 weeks, and remarkable decrease was shown in the Y.S.T. (12.5ml/kg) dosed group after 2 weeks of experiment. 4. The volume of the phospholipid in the diabetic rats, was decreased significantly in the Y.S. T. (12.5ml/kg) dosed group after 2 weeks of experiment. S. The volume of total protein of diabetic rats, was increased in all group, and the remarkable increase was shown in the Y.S.T. (1.25ml/kg) dosed group after 4 weeks. 6. The volume of the sodium in the Y.S.T. (1.25ml/kg) dosed group, was notably increased in 2 weeks, and remarkable decrease of potassium in serum was shown, in each Y.S.T. dosed group (1.25ml/kg, 12.5ml/kg) after a week of experiment. According to above results,It is expected that Y.S.T. applied to SOYANGIN, can be used for medical treatment of diabetes with effect. But because the effect can be somewhat different depending upon dosage, appropriate operation on clinic is needed, for the best curing effect.