This meta-analysis aggregated and analyzed the research in studying the pretest-posttest outcomes of VR-based interventions for children and young adults with ASD. Seven studies published between 2009 and 2019 with a total of 150 participants were included. Outcome measures of social competences were classified into 5 categories. The random-effects model of the current meta-analysis showed that the average effect of VR-based intervention as follows: social skills(g = .59, SE = .12, 95% CI: .35–.82), emotion recognition(g =. 50, SE = .16, 95% CI: .19–.82), attention(g = .35, SE = .14, 95% CI: .07–.63), executive function(g = .52, SE = .12, 95% CI: .28–.77) and conversational skills(g = .46, SE = .21, 95% CI: .05–.88). The implication for VR-based intervention s for ASD was discussed with respect to environmental factor such as age, ASD functioning, number of sessions, country where the study conducted and additional treatment combined.