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2020, Vol.10, No.4

  • 1.

    Ethno-pharmacology of Sahdevi (Vernonia cinerea Less.) - An important but lesser known drug of Unani System of Medicine

    Mohammad Zakir , Safiya Khanam , Munawwar Husain Kazmi | 2020, 10(4) | pp.26~26 | number of Cited : 0
    Abstract PDF
    Sahdevi is an Indian herb commonly found in all part of the country in rainy season. It is adopted by Arabs due to its easy availability and various important pharmacological actions and uses. It is known by different vernaculars in different parts of the country such as Mahabala in Marathi, Sadodi in Gujrati, Kukseem in Bengali and in English it is called ash-colour fleabane or purple fleabane. The herb contains β-amyrin, lupeol, β-sitosterol, stigmasterol, α-spinasterol, phenolic resin and potassium chloride etc. It contains Dafi‘-i Hummiyat (antipyretic) Muqawwi-i Badan (general tonic) and Musaffī-i-Dam (blood purifier) actions and used for management of many disease conditions. It has been used for the management of chronic fevers like fever associated with tuberculosis. It is a priceless herb with important pharmacological action and can be used effectively in place of costly drugs.
  • 2.

    In-Vitro Anticancer and Free Radical Scavenging Potential of Compound Formulation Used in Unani System of Medicine

    Mohd Nazir Mannan , Munawwar Husain Kazmi , Alokananda Chakraborty and 3 other persons | 2020, 10(4) | pp.27~27 | number of Cited : 0
    Abstract PDF
    Cancer is one of the leading cause of mortality in India as well as worldwide. The management of cancer by conventional therapy has shown life threatening adverse effects. The researchers are now exploring the natural way of treatment. Unani system of medicine have rich literature for cancer and many compound formulations have been described in this system. Unani system of medicine is based on holistic approach and treat human being as a unit with natural herbs, mineral and animal origin drugs. An important compound Unani formulation (CUF) from the literature has been chosen to explore the Unani claim of its anticancer activity. The phytochemical constituents were assessed using standard phytochemical screening method. Antioxidant property of this formulation was assessed by DPPH assay. The DPPH free radical scavenging assay was carried out by colorimetric method and ascorbic acid was taken as a positive control. Three different extracts of CUF on different concentrations were used to screening on human breast cancer (BCC) MCF-7 cell line. For the estimation of in-vitro cytotoxic potency of the investigated extracts was assessed on MTT assay by using trypan blue method and paclitaxel was used as the standard. Hydro-ethanolic (HE) extract showed highest free radical scavenging activity among all extracts. DPPH Assay showed substantial antioxidant activity of these extracts in hydro-ethanol extract at 1µg concentration of CUF. The CUF showed antioxidant and anticancer activity. The claim made by Unani physician has been proved.
  • 3.

    A Study on the analysis of Whitney Houston, the healer of the world-based on Shin Jae-hyo's gwangdaeron (clown theory)

    Kyung Ja Ko , Cho Hyunyong | 2020, 10(4) | pp.28~28 | number of Cited : 0
    Abstract PDF
    The purpose of this study is to find out why Whitney Houston gave healing to people around the world based on Shin Jae-hyo's gwangdaeron (clown theory). In Korean music, gwangdae (廣大, the title of clown) is a nickname dedicated to outstanding artists. Not only is it a clown that cannot be a person, but it does not give a clown a nickname for doing art activities. This is why Shin Jae-hyo, a pansori (Pansori epic chant) theorist and critic in the late 19th century of the Joseon Dynasty, presented the virtues of outstanding artists. There are four outstanding clown conditions claimed by Shin Jae-hyo: appearance (人物), words (辭說), perfect vocal music (得音) and wonderful movements (neoreumsae). These conditions show how difficult it is to be a gwangdae (a prominent artist), or an accomplished artist. We think Whitney Houston is a famous singer who fits these conditions. In her heyday, she was optimized for Shin Jae-hyo's clown theory, while her post-2007 moves are regrettable. However, it is clear that he is a singer who fits well with the title of America's greatest clown. In conclusion, I felt that the best emotion through music was the best healing, and that the best singer was becoming the best healer.
  • 4.

    Preparedness of Siddha system of medicine in practitioner perspective during a pandemic outbreak with special reference to COVID-19

    S. Rajalakshmi , K. Samraj , P. Sathiyarajeswaran and 1 other persons | 2020, 10(4) | pp.29~29 | number of Cited : 0
    Abstract PDF
    COVID-19 (Corona Virus Disease-2019) is an infectious respiratory disease caused by the most recently discovered coronavirus, SARS-CoV-2 (Severe Acute Respiratory Syndrome Corona virus-2). This new viral disease was unknown before the outbreak began in Wuhan, China, in December 2019. As of November 16th 2020, it affects about 54.3 million populations, death troll increased to 1.32 million cases in worldwide. Whereas in India 8.85 cases are infected with COVID-19, of which 1, 30, 112 cases were died. Till now there has been no specific anti-virus drug or vaccines are available for the treatment of this disease, the supportive care and non-specific treatment to the symptoms of the patient are the only options in Biomedicine, the entire world turns its attention towards alternative medicine or Traditional medicine. Siddha medicine is one of the primordial systems of medicine practiced in the southern part of India, it dealt a lot about pandemic, and its management. This review provides an insight into Pandemic in Siddha system and its management in both ancient history and modern history, National and state level Government policies related to current pandemic, World Health Organization (WHO) guidelines on usage of unproven drug during infectious disease outbreak, Preparedness of Siddha system during a pandemic outbreak Challenges and Recommendations.
  • 5.

    Evaluation of Anti-venom effect of Tiryaq-e-arba in rabbit models

    Mohd. Tarique Ahsan , Seema Rani | 2020, 10(4) | pp.30~30 | number of Cited : 0
    Abstract PDF
    Background: Tiryaq-e-arba is a polyherbal Unani antidote/antivenom formulation used in the management of poisoning due to snake bite, scorpion bite as well as in cold poisons since time immemorial. Objectives: Tiryaq-e-arba was not evaluated scientifically before this study carried out, therefore it was studied for antivenom activity by testing on plasma fibrinogen level in Russell’s Viper envenomation in rabbits. Material &Methods: The anti-venom activity of the test drug was studied by observing its effect on plasma fibrinogen level in Russell’s Viper envenomation in rabbits by the method of Netelson. Results: The plasma fibrinogen level was found to be 171±665.04 mg/100 ml of blood, 36.18±1.12 mg/100 ml of blood, 33.14±0.52 mg/100 ml of blood and 17.9±1.65 mg/100 ml of blood at 0, 1, 3 and 6 hours respectively in control animals while in the test animal it was found to be 157.13±3.44 mg/100 ml of blood, 41.13±2.69 mg/100 ml of blood, 62.09±1.65 mg/100 ml of blood and 54.39±0.73 mg/100 ml of blood respectively. The test showed that though the plasma fibrinogen level in the test lower at 0 hour but it was greater in the control animals at 1, 3 and 6 hours. The increase in plasma fibrinogen level in the test animals at 3 and 6 hours was statistically significant (P<0.001). Conclusions: The finding of the present study was that Tiryaq-e-arba possesses antivenom activity which scientifically support the Unani claim that it is Dafe-Sumoom-al-Hevan (Antivenom or Antidote) and the use of this preparation in corresponding diseases.
  • 6.

    A Clinico-epidemiological Profile of Dyslipidaemia and its Association with Temperament - A Cross Sectional Study

    Qurratulain , Mohammad Nawab , M.H. Kazmi | 2020, 10(4) | pp.31~31 | number of Cited : 0
    Abstract PDF
    Introduction: Dyslipidaemia is directly associated with cardiovascular diseases. Temperament, the unique constitutional make-up of an individual, is responsible for one's personality traits, physical appearances, and disease predispositions. The rising prevalence of dyslipidaemia becomes a challenge to control morbidity and mortality due to cardiovascular diseases. Objective: To study clinical patterns and risk factors of dyslipidaemia and its association with temperament at the individual level was the main objective of this study. Materials and Methods: It was a descriptive and analytical cross sectional study. The participants (n=88) were screened on the basis of raised serum lipid profile from the outpatient department of National Research Institute of Unani Medicine for Skin Disorders, Hyderabad. The data were collected on a case record form designed for this study and analyzed retrospectively. Results: In this study, there were 57% participants (n=50) of phlegmatic temperament in which mean total cholesterol, triglycerides, low density lipoprotein- cholesterol and high density lipoprotein-cholesterol were 230.92 (±49.48) mg/dl, 182.34 (±110.61) mg/dl, 153.24 (±50.21) mg/dl and 46.3 (±10.83) mg/dl respectively. Discussion: This study showed the prevalence of different clinical patterns of dyslipidaemia in the population and the phlegmatic participants were dyslipidaemic in a higher percentage. The prevalence of dyslipidaemia in phlegmatic participants may be linked to the constitutional make-up of the individual. The temperament of an individual may be considered as one of the risk factors for dyslipidaemia. Conclusion: It was concluded that the temperament of an individual may be used as a screening tool to predict the individual’s tendency to develop dyslipidaemia.