The purpose of this study was to identify the main effects and mediating effects of university students' self-directed learning and creative school environment by deriving self-directed learning ability and creative school environment as influencing variables to foster creativity. Therefore, the subjects of the study were 511 college students who took online self-directed learning classes in the second semester of 2020 at S University in Seoul. The subjects conducted self-directed tests covering learning skills, creative school environment, and creativity. The collected data were statistically processed using the SPSS 25.0 and JAMOVI 1.2.27 programs. As a result of the study, there was a positive correlation between self-directed learning ability and creative school environment and creativity, and it was confirmed that the self-directed learning ability of university students influenced creativity through a creative school environment. Therefore, it is necessary to recognize the importance of a creative school environment in composing the curriculum for improving the creativity of university students. The self-directed learning ability of students must be considered, and how to construct a creative school environment to improve the creativity of students. It will be necessary to discuss whether to establish the curriculum and educational environment.