Detection of Streptococcus mutans in Saliva using Monoclonal Antibodies

이민정; 이대우; Miah Kim; Lee Kyung-Yeol; Byeong Ju Baik; Yang Yeon Mi; KIM JAE GON

doi:10.5933/JKAPD.2015.42.1.10

The purpose of this study was to determine the usefulness of a detection method for Streptococcus mutans insaliva with monoclonal antibodies developed targeting Ag I/II and glucosyltransferases (gtf B, gtf C and gtf D) inStreptococcus mutans. In the three groups tested (adults, minors, and minors under orthodontic treatment), theresults of the DMFT scores, the colony density (CFU/mL) in their saliva was measured using Dentocult-SMstrip mutans, polymerase chain reaction was performed to test whether Streptococcus mutans and Streptococcussobrinus were present, and Streptococcus mutans detecting tests performed in their saliva using four types ofmonoclonal antibody were collected. In conclusion, it was demonstrated that the Streptococcus mutants plays more important role in forming dentalcaries compared to Streptococcus sobrinus, and that the monoclonal antibodies against glucosyltransferases(gtf B, gtf C, gtf D) and Ag I/II of Streptococcus mutans are superior in detecting Streptococcus mutans toDentocult-SM strip mutans or polymerase chain reaction.

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* 2021년 이후 발행 논문의 참고문헌은 현재 구축 중입니다.

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