Blood Gas Analysis of Respiratory Depression during Sevoflurane Inhalation Induction for General Anesthesia in the Disabled Patients

Taewan Yoon; kim seung oh

doi:10.5933/JKAPD.2018.45.4.508

Tidal volume by sevoflurane in small amounts is stable due to the increase in the breathing rate. But alveolus ventilation decreases due to sevoflurane as the degree of sedation increases; this ultimately causes PaCO2 to rise. The occurrence of suppression of breath increases the risk of severe hypoxia and hypercapnia in deeply sedated patients with disabilities. Sevoflurane inhalation anesthesia has a number of risks and may have unexpected problems with hemodynamic changes depending on the underlying state of the body. This study was conducted to examine the stability of internal acid-base system caused by respiratory depression occurring when patients with disabilities are induced by sevoflurane. Anesthetic induction was carried out by placing a mask on top of the patient’s face and through voluntary breathing with 4 vol% of sevoflurane, 4 L/min of nitrous oxide, and 4 L/min of oxygen. After the patient’s loss of consciousness and muscle relaxation, IV line was inserted by an expert and intravenous blood gas was analyzed by extracting blood from vein. In a deeply sedated state, the average amount of pH of the entire patients was measured as 7.36 ± 0.06. The average amount of PvCO2 of the entire patients was measured as 48.8 ± 8.50 mmHg. The average amount of HCO3 - of the entire patients was measured as 27.2 ± 3.0 mmol/L. In conclusion, in dental treatment of patients with disabilities, the internal acid base response to inhalation sedation using sevoflurane is relatively stable.

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* 2022년 이후 발행 논문의 참고문헌은 현재 구축 중입니다.

[journal] 김승오 / 2013 / A SURVEY OF GENERAL ANESTHESIA, SEVOFLURANE SEDATION AND INTRAVENOUS SEDATION IN CHUNGNAM DENTAL CLINIC FOR THE DISABLED / 대한소아치과학회지 / 대한소아치과학회 40(1) : 28~39

[journal] 서광석 / 2009 / Clinico-statistical Analysis of Cooperation and Anesthetic Induction Method of Dental Patients with Special Needs / Journal of Dental Anesthesia and Pain Medicine / 대한치과마취과학회 9(1) : 9~16

[journal] 신비솔 / 2016 / A survey of dental treatment under general anesthesia in a Korean university hospital pediatric dental clinic / Journal of Dental Anesthesia and Pain Medicine / 대한치과마취과학회 16(03) : 203~208 / http://dx.doi.org/10.17245/jdapm.2016.16.3.

[journal] Saraswat V / 2015 / Effects of anaesthesia techniques and drugs on pulmonary function / Indian J Anaesth 59 : 557~564

[book] The Korean Dental Society of Anesthesology / 2015 / Dental Anesthesiology / Koonja : 431~433

[journal] Strum DP / 1987 / Partition coefficients for sevoflurane in human blood, saline, and olive oil / Anesth Analg 66 : 654~656

[journal] Smith I / 1996 / Sevoflurane-a long awaited volatile anaesthetic / Br J Anaesth 76 : 435~445

[journal] Larson CP Jr / 1969 / The effects of diethyl ether and methoxyflurane on ventilation: II. A comparative study in man / Anesthesiology 30 : 174~184

[book] Hickey RF / 1981 / Regulation of breathing: Drug effects / Marcel Dekker : 1251~

[journal] Fourcade HE / 1971 / The ventilatory effects of Forane, a new inhaled anesthetic / Anesthesiology 35 : 26~31

[journal] Eger EI 2nd / 1981 / Isoflurane: a review / Anesthesiology 55 : 559~576

[journal] Schwieger I / 1989 / Lung function during anesthesia and respiratory insufficiency in the postoperative period: physiological and clinical implications / Acta Anaesthesiol Scand 33 : 527~534

[book] Ward DS / 1997 / Neuropharmacology of the control of ventilation / Lippincott-Raven : 1367~1394

[journal] Levesque PR / 1975 / Acid-base disorders: application of total body carbon dioxide titration in anesthesia / Anesth Analg 54 : 299~307

[journal] Berger AJ / 1977 / Regulation of respiration / N Engl J Med 297 : 194~201

[journal] Becker DE / 2008 / Nitrous oxide and the inhalation anesthetics / Anesth Prog 55 : 124~130

[book] Eilers H / 2007 / Basics of Anesthesia / Churcill Livingstone Elsevier : 97~111

[journal] Williams AJ / 1998 / ABC of oxygen: assessing and interpreting arterial blood gases and acid-base balance / BMJ 317 : 1213~1216

[journal] Rao SM / 2002 / Arterial blood gas monitoring / Indian J Anaesth 46 : 289~297

[journal] Holaday DA / 1981 / Clinical characteristics and biotransformation of sevoflurane in healthy human volunteers / Anesthesiology 54 : 100~106

[book] The Korean Dental Society of Anesthesology / 2015 / Dental Anesthesiology / Koonja : 512~

[journal] 박창주 / 2004 / Inhalational Deep Sedation Using Sevoflurane in Pediatric Dental Patients / Journal of Dental Anesthesia and Pain Medicine / 대한치과마취과학회 4(2) : 90~95

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