The change of the photoluminescence properties of La2O3-CaF2-Al2O3-SiO2 glass-ceramics doped with rare earthmaterial, that is used as laser and optical sensors, was analyzed according to heat treatment temperature. The heat treatmentconditions for fabricating glass-ceramics were obtained through non-isothermal thermal analysis, and X-ray diffraction analysiswas performed to determine the degree of crystal growth and kinds of crystal phases generated according to the heat treatmenttemperature. Using Scherrer’s equation, it was predicted that crystals with a size of 25~40 nm would be generated insidethe glass-ceramics. Photoluminescence (PL) analysis showed that the specimens heat-treated at 660°C to 670°C for 1 hourhad the highest PL intensity. Also, from the CIE color coordinate analysis, all glass-ceramics specimens emitted red-orangelight regardless of the heat treatment condition.