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2010, Vol.20, No.1

  • 1.

    Effects of Cool Pharmacopuncture for Static Blood into Hyolhae(Sp10 ) on Neurological Recoverment and BAX, BCL-2 Expression in the Experimental Traumatic Brain Injury Rats

    조주현 | Jin-Bong Choi | 2010, 20(1) | pp.1~12 | number of Cited : 0
    Abstract
    Objectives :Cool Pharmacopuncture for static blood is a famous pharmacopuncture treatment that treated disease caused by static blood. Hyolhae(Sp10) is also a famous point of acupuncture that treated that. This study was designed to evaluate the effects of Cool Pharmacopuncture for static blood into Hyolhae(Sp10) on BAX and BCL-2 expression in the experimental traumatic brain injury(TBI) rats. Methods :Male rats were divided into 3 groups. Ⅰ was no treatment after TBI. Ⅱ was treatment with needle-prick acupuncture after TBI. Ⅲ was treatment with Cool Pharmacopuncture for static blood into Hyolhae(Sp10) after TBI. The author carried out neurological motor behavioral test, histological assessment test. Neurological motor behavior tests consist of rotarod test, beam-walking test and postural reflex test. In the histological assessment test, BAX and BCL-2 expression, hematoxylin & eosin staining were experimented. Results :In neurological motor behavior tests, motor and cognitive function recovery was significantly increased in the Ⅱ, Ⅲ as compared with Ⅰ(p<0.05). Especially Ⅲ was significantly increased as compared with Ⅱ(p<0.05). BAX expression was significantly decresed in order of the Ⅲ, Ⅱ, Ⅰ after 7 and 14days later. BCL-2 expression was investigated in the Ⅲ, Ⅱ as compared with Ⅰ. Especially Most incresed expression was experimented in the Ⅲ. Conclusions :According to the above results, Cool Pharmacopuncture for static blood can inhibit apoptosis of cells after TBI in rats by contol of BAX and BCL expression.
  • 2.

    Neuroprotective Effects of Neutral Pharmacopuncture for Blood Stasis and Tangguisusangami-tang(dangguixusanjiawei-tang ) in the Experimental Traumatic Brain Injury Rats

    정일문 | Jin-Bong Choi | 2010, 20(1) | pp.13~26 | number of Cited : 3
    Abstract
    Objectives :This study was designed to evaluate neuroprotective effects of Neutral Pharmacopuncture for Blood Stasis(NPBS) into SP10 and Tangguisusangami-tang (dangguixusanjiawei-tang)(TGT) in the experimental Traumatic Brain Injury(TBI) rats. Methods :Male rats were divided into 4 groups. Group Ⅰ was no treatment after TBI. Group Ⅱ was treatment with NPBS into SP10 after TBI. Group Ⅲ was treatment with TGT after TBI. Group Ⅳ was NPBS into SP10 and TGT after TBI. The author carried out neurological motor behavioral, histological assessment test. Results :1. In neurological motor behavior tests, motor and cognitive function recovery was significantly increased in the Group Ⅱ, Ⅲ, Ⅳ. Also Group Ⅳ was increased as compared with Group Ⅱ, Ⅲ. 2. In BAX expression, according to priority Group Ⅳ, Ⅲ, Ⅱ, Ⅰ were decresed in 7 and 14 days later. Especially Group Ⅳ was significantly decreased in 14days later. 3. In BCL-2 expression, Group Ⅳ was increased slightly in 7days later. Most incresed expression was experimented in the Group Ⅳ in 14days later. 4. In TUNEL expression, Ⅳ was decreased as compared with each Group Ⅰ,Ⅱ, Ⅲ in 7days later. Group Ⅳ, Ⅲ were decreased as compared with each Group Ⅰ,Ⅱ in 14days later. Conclusions :According to the results, NPBS and TGT can inhibit apoptosis of cells after TBI in rats by contol of BAX and BCL-2, TUNEL expression. And also can help neurological motor behavioral function.
  • 3.

    Suppress Effects of Euiiin-tang( ) Aqueous Extracts on Collagen Induced Arthritic(CIA) DBA/1 Mice

    조중현 | 권오곤 | 우창훈 and 1other persons | 2010, 20(1) | pp.37~60 | number of Cited : 10
    Abstract
    Objectives :The object of this study was to observe the favorable anti arthritic effects of Euiiin-tang(yl̀y˘l nrén-tāng) aqueous extract(EIITe), has been traditionally used in Korean medicine for treating rheumatoid arthritis on collagen induced arthritic(CIA) DBA/1 mice. Methods :In the present study, effects of EIITe on the releases of human tumor necrosis factor(TNF)-α, interleukin(IL)-1β, matrix metalloproteinase(MMP)-13 and production of Nitric oxide(NO) were observed by in vitro. In addition, to observe the effects on the CIA mice, three different dosages of EIITe, 300, 150 and 150 mg/kg were orally administered once a day for 18 days from 24hrs after antigen challenges(type II collagen) on 21 days after immunization using Type II collagen Freund’s complete adjuvant. Six groups, each of 8 DBA/1 mice per group were used in the present study as follows. Changes on the body weights, macroscopic arthritis scores, splenic weights, splenic TNF-α and IL-6 contents, articular cartilage(femur and tibia) collagen and glycosaminoglycans -chondroitin sulphate, sulphate and hyaluronic acid contents, histopathological observations(microscopic arthritis scores, thicknesses of femur and tibia cartilage thicknesses were monitored, compared to that of dexamethasone, a potent anti inflammatory agents, 1 mg/kg treated mice. Results :As results of collagen challenges, marked decreases of body weights and gains, articular cartilage collagen and glycosaminoglycan - chondroitin sulphate, sulphate and hyaluronic acid contents were observed with increases of macroscopic arthritis scores, splenic weights, splenic TNF-α and IL-6 contents, articular cartilage(in the both femur and tibia) loss and damages. However, these CIA signs were significantly and dosages dependently inhibited by treatment of EIITe 300 and 150 mg/kg as compared with CIA control, respectively. In addition, the releases of TNF-α, IL-1β, NO and MMP-13 were markedly and dose dependently inhibited by treatment of EIITe, in vitro. Although CIA were more favorably inhibited by treatment of dexamethasone 1 mg/kg as compared with EIITe 300 mg/kg, marked decreases of body weights were detected in dexamethasone 1 mg/kg treated mice. Conclusions :The results obtained in this study suggest that over 150 mg/kg of EIITe showed favorable anti‐arthritic effects on the CIA mediated by immunomodulatory and/or anti‐oxidative effects. However, detail mechanism studies should be conduced in future with the screening of the biological active compounds in this herb. lthough CIA were more favorably inhibited by treatment of dexamethasone 1 mg/kg as compared with EIITe 300 mg/kg, marked decreases of body weights were detected in dexamethasone 1 mg/kg treated mice, in the present study.
  • 4.

    Effects of Bee Venom and Cervi Cornu Parvum Pharmacoacupuncture in Monosodium Iodoacetate(MIA)-Induced Osteoarthritis Rat

    김환영 | Jin-Bong Choi | 2010, 20(1) | pp.61~77 | number of Cited : 13
    Abstract
    Objectives :The purpose of this study was to investigate the effects of Bee Venom (BV) and Cervi Cornu Parvum pharmacoacupuncture (CC) in monosodium iodide induced arthritis rats. Methods :The subjects were divided into 5 groups ; Normal, Control (no treatment after MIA), BV (Bee Venom pharmacoacupuncture 100 ㎕ daily at Dokbi (ST35) after inducing MIA), CC (Cervi Cornu Parvum pharmacoacupuncture 100 ㎕ daily at Dokbi (ST35) after inducing MIA) and BV+CC (Bee Venom pharmacoacupuncture and Cervi Cornu Parvum pharmacoacupuncture 100 ㎕ daily at Dokbi (ST35) after inducing MIA). After each operation, the present author observed the motor behavior recovery, hematological (Prostaglandin E2, AST, ALT), histological and immunological changes. Rats were tested at the 7th, 14th and 21st day. Results :Results are as follows. 1. All the experimental groups were improved compared with control group in plantar test. 2. All the experimental groups were improved compared with control group in touch test for sensory evaluator. 3. All the experimental groups were significantly decreased compared with control group in prostaglandin E2. 4. In histological observations, knee joint in all the experimental groups were improved compared with control group. 5. In immunological observations, all the experimental groups were significantly decreased compared with control group in COX-1, 2. Conclusions :It can be suggested that Bee venom and Cervi Cornu Parvum pharmacoacupuncture may improve motor behavior, hematological, histological and immunological findings in MIA-induced osetoarthritis rats. Especially, combination of these two treatments will be somewhat better in osteoarthritis recovery and motor function improvement.
  • 5.

    The Effects of Tai Chi for Arthritis on Chronic Arthritic Pain of Senior Female : A Pilot Study

    황의형 | Jeonghwan Kim | Jang Insoo and 2other persons | 2010, 20(1) | pp.79~90 | number of Cited : 4
    Abstract
    Objectives :Tai Chi for arthritis was developed in 1997 by Paul Lam, M.D. of family medicine in Australia. It is an exercise treatment program and a good approaching method for arthritis. However its application is limited to arthritis of knee joint only. Even there have been no clinical study in korean traditional medical society. The aim of this study is to investigate effect of the Tai Chi for arthritis on chronic pain of body. Methods :We designed this trial as objectives were (1) senior female over 60 years, (2) suffering for osteoarthritis and chronic body pain, (3) have no physical or mental dysfunctions (4) able to walk and exercise alone. Objectives mactched these criteria had been trained the Tai Chi for arthritis 2 hours a day for 21 weeks. Before and after training, pain of 8 joints(neck, shoulder, elbow, wrist, waist, hip, knee, ankle) were estimated with the VAS(Visual Analog Scale). Results :Training the Tai Chi for arthritis relieved multiple joint pain(especially neck, lower back, shoulder, wrist and knee) and these were statistically significant. Conclusions :This study is a pilot study to investigate effect of the Tai Chi for arthritis on chronic pain of whole body. Absence of control group, and other scale to test joint function except VAS were limitations of this study. It is the first clinical approach about Tai Chi in korean medicine field, also the first study of Tai Chi for pain of the whole body.
  • 6.

    A Literature Review of Herbal Medicines on Osteoporosis Studies - Reviewing Articles Published after Year 2000

    김민범 | 김성수 | Chung, Seok Hee | 2010, 20(1) | pp.91~107 | number of Cited : 5
    Abstract
    Objectives :The purpose of this study was to investigate which herbs and herbal formulae are frequently used for the treatment of osteoporosis since 2000. Methods :We searched the CENTRAL, MEDLINE, AMED, CINAHL, Scopus, KISS, KoreaMED, KERIS, Kmbase, Dbpia, J-STAGE, CNKI, J Oriental Rehab Med., J Korean Oriental Med., J Oriental Gynecol. using search key words osteoporosis, osteopenia, bone density and bone loss combined with herbal, botanical plant and phytomedicine. Results :73 studies were reconfirmed and 83 herbs have been found. For single herb, most of them were categorized into Boyik-yak(補益藥, Buyi-yao). For herbal formulae, various herbal formulae are used. Calculating each herb in consisted in each herbal formula, Angelica Gigas Radix(當歸) and Rehmanniae Radix Preparat(熟地黃) turned out to be the most frequently used herb. Conclusions :Further studies regarding herbal medicines on osteoporosis are needed.
  • 7.

    The Different of Yangdorak Diagnosis between Low Back Pain Patients and Medical Checkup Group in Korean Males

    김민범 | 김성수 | Jongsoo Lee | 2010, 20(1) | pp.109~117 | number of Cited : 7
    Abstract
    Objectives :The aim of this study was to investigate the different of yangdorak diagnosis between low back pain patients and medical checkup group. Methods :We analyzed the measurement value of yangdorak on 103 patients with low back pain and 103 medical checkup persons in Korean males from March 1st, 2007 to September 30th, 2008 by using yangdorak(MEDIRA, Neomyth Co., Korea). Results :1. In comparing results on the yangdorak general mean, low back pain group is statistically significant in comparison with medical checkup group(p<0.001). 2. In comparing results on each meridian yangdorak value, they were statistically significant between two groups(p<0.001). 3. In comparing result on the distance of yangdorak value from the mean, they were statistically significant between two groups at the Bladder- meridian(p<0.05), but not at the Kidney-meridian. Conclusions :This results suggest that yangdorak may be used for a method to objective clinical examination. But further studies are required for a use of practical indicator.
  • 8.

    The Effects of Psychological Stress on Neck Muscles

    권호영 | Jeonghwan Kim | 2010, 20(1) | pp.119~132 | number of Cited : 1
    Abstract
    Objectives :The purpose of this study is to compare interrelations between stress and muscles of neck through stress response inventory(SRI), 7 zone diagnostic system and surface electromyography(sEMG). Methods :This study was carried out with the data from SRI, 7 zone diagnostic system and sEMG. First subjects were divided into two group according to the SRI points. subjects in group A had points of SRI in which lower than 30 points. Subjects in group B had points of SRI in which higher than 30 points. And subjects were divided into nonstress group(Group C) and stress grouop(Group D) according to the result of 7 zone diagnostic system. Then we investigated how to differentiate the muscle contraction, fatigue, recovery and asymmetry ratio on sEMG for each groups. Results :In this study, the muscle contraction of both upper trapezius muscle and left sternocleidomastoid muscle and left scalene muscle in stress group were higher than nonstress group significantly. And the muscle recovery of left sternocleidomastoid muscle and left scalene muscle in stress group were higher than nonstress group significantly. Conclusions :This results show that the stress was associated with muscle condition.
  • 9.

    The Study of Comparison about Pain and Fatigue according to Cervical Spine Curvature of Patient with Neck Pain

    이한길 | 전태동 | 홍서영 | 2010, 20(1) | pp.133~139 | number of Cited : 5
    Abstract
    Objectives :The purpose of this study was to compare about quantity of pain and fatigue according to cervical spine curvature of patient with neck pain Methods :Cervical spine curvature was measured using the sagittal radiography of the cervical spine, neck pain was evaluated using the VAS and neck fatigue was evaluated using fatigue symptom checklist. Based on four line Cobb's method, 51 subjects were divided into hypolordosis group, normal group, hyperlordosis group. Window version SPSS 12K was used for statistical analysis about relation between pain and cervical spine curvature of each group, also about between fatigue and cervical spine curvature of each group. Results :1. A significant difference was not found between pain and cervical curvature of each group. 2. A significant difference was not found between fatigue and cervical curvature of each group. Conclusions :There was no relation between pain and cervical curvature of each group, also fatigue and cervical curvature.
  • 10.

    The Comparative Study on the Effect of Acupuncture Treatment with or without Indirect Moxibustion Treatment for Acute Ankle Sprain

    우창훈 | 권오곤 | 안희덕 | 2010, 20(1) | pp.141~152 | number of Cited : 2
    Abstract
    Objectives :The purpose of this study is to compare with the effect of acupuncture treatment with or without indirect moxibustion treatment for acute ankle sprain. Methods :This study was carried out on the 48 patients who had been treated for acute ankle sprain from June 1st to November 30th 2009 in the Dept. of Oriental Rehabilitation, Pohang Oriental Medical Hospital, Daegu Hanny University. The patients were divided into 3 groups ; Group A took near acupuncture point needling, Group B took remote acupuncture point needling, Group C took remote acupuncture point needling with indirect moxibustion. 3 Groups had been co-treated with rest, ice, compression and elevation(RICE) therapy, physical treatment and administered Ojeok-san(Wuji-san) extract granule. To evaluating the efficiency of each treatment, Ankle-Hindfoot Scale(AHS) and Visual Analogue Scale(VAS) were applied before treatment and after 3rd treatment. Results :In results, the AHS scores were increased and the VAS scores were decreased after 3rd treatment in all group. Also, AHS scores and the VAS scores of intergroup were showed no significant change. Conclusions :In this study, there is no significant effect between only acupuncture treatment and moxibustion co-treatment for acute ankle sprain.
  • 11.

    A Study on the Significance of Sanghanron Prescription in Traffic Accident Patient

    전태동 | Minseok Oh | 2010, 20(1) | pp.153~166 | number of Cited : 7
    Abstract
    Objectives :The aim of this study is to make proof of availability for Sanghanron prescription. Methods :The study group comprised 80 Koreans, male:female ratio of 31:49, with mean age of 40.78 years. The SF-MPQ and PDI were checked hospitalized and discharged patients. Results :1. The most uesd prescription is Galgeun-Tang(Gegen-tang) and the other 30 prescriptions were uesd. 2. Hospitalized patients, there was significant difference in SF-MPQ and PDI scores(P<0.05). 3. The treatment was effective to 72 patients out of 80 who had been hospitalized for less than 14 days. 4. Experimental group compared with Lee`s thesis was significantly difference in 7 days of treatment, but the other compared were not significant difference. Conclusions :This data suggested that the Sanghanron prescription could be effective treatment about traffic accidental patients without surgical injury. Further study is needed about the effectiveness of Sanghanron prescription.
  • 12.

    A Study on the Correlation about 7-Zone-Diagnostic System and Clinical Parameters

    조웅희 | 박원형 | Cha Yun Yeop | 2010, 20(1) | pp.167~182 | number of Cited : 1
    Abstract
    Objectives :The purpose of this study is to find correlation about 7-Zone-Diagnostic System and Clinical Parameters using Oriental Health Examination. Methods :Subjects of our study were 325 cases who took Oriental Health Examination. We collected the data of body composition analysis, 7-Zone-Diagnostic System, blood analysis and devided by 7-Zone-Diagnostic system to acceleration, normalcy and depression. Results and Conclusions :The values of muscle mass, body fat mass, abdomen obesity rate, right arm water index, left arm water index, trunk water index, right leg water index, left leg water index, BMI, BMR, GOT, GPT, γ-GTP, BUN, TC, triglyceride and hemoglobin were continuous with 7-Zone-Diagnostic system.
  • 13.

    The Clinical Effects of Low Level Laser Therapy on Shoulder Pain

    Kyungmoo Park | 이길재 | SONG YUN KYUNG and 1other persons | 2010, 20(1) | pp.183~192 | number of Cited : 3
    Abstract
    Objectives :The purpose of this study is to investigate the clinical effects of low level laser therapy on shoulder pain. Methods :From October 1, 2009 to November 14, 2009, we applied 15 participants who consented to an assignment had a shoulder pain to low level laser therapy(LLLT). We treated LLLT 8 times on both upper trapezius, levator scapular, pectoralis, suboccipital, rhomboid, rotator cuff tender point for 2 weeks. To evaluate the efficiency of low level laser therapy, we used questionnaire of shoulder pain symptom, questionnaire of a day living discomfort scale, shoulder pain and disability index(SPADI) and pressure pain threshold(PPT) at before treatment and after treatment 4 times and 8 times. Results :There was a significant difference in questionnaire of shoulder pain symptom, questionnaire of a day living discomfort scale, SPADI and PPT after 8th treatment. Conclusions :Low level laser therapy for shoulder pain is effective to improve patients' symptoms measured with questionnaire of pain and a day living discomfort score, SPADI and PPT significantly.
  • 14.

    The Clinical Effects of Cupping Therapy at Bedtime for Sleep Disorder Induced by Traffic Accidents

    Lee Eun Jung | 전태동 | Yoon il ji and 1other persons | 2010, 20(1) | pp.193~208 | number of Cited : 5
    Abstract
    Objectives :The purpose of this study is to investigate the clinical effects of cupping therapy on sleep disorders induced by traffic accidents. Methods :The 46 patients were divided into 2 groups : Exp.group was treated with cupping therapy at bedtime and Con.group was treated except cupping therapy at bedtime. To evaluate the efficiency of cupping therapy, the SMH sleep questionnaire and Visual Analogue Scale(VAS) were applied before treatment and after 7 days treatment. Results :1. The Exp.group has improved statistical significantly in delaying bedtime and bedtime arousal as compared to the Con.group. 2. The Exp.group was increased in total sleep time but had no statistical significance as compared to the Con.group. 3. The Exp.group was improved in subjective evaluation of satisfaction with sleep, depth of sleep, the overall sleep and difficulty in falling asleep. Conclusions :Cupping therapy at bedtime has clinical effects of improvement of sleep disorder induced by traffic accidents
  • 15.

    Calcific Tendinitis of the Shoulder by Oriental Medical Treatments : 4 Cases Report

    Seung-ryong Yeom | 송정훈 | 2010, 20(1) | pp.209~217 | number of Cited : 3
    Abstract
    This study was performed to report the effect of oriental medical treatments on the 4 patients with calcific tendinitis of the shoulder. The 4 patients were treated by cupping, acupuncture, pharmacopuncture on tender points of the greater tuberosity of humerus. The state of patients was measured by visual analog scale(VAS) and shoulder range of motion(ROM). After mean 3.25 times of treatments, the significant recovery of shoulder ROM was measured and the significant pain relief was seen as the average of VAS changed from 8.5 to 1. These results suggest that oriental medical treatments including cupping, acupuncture, pharmacopuncture are effective to improve the calcific tendinitis of the shoulder. However more rigorous study should be followed.
  • 16.

    The Effect of Intra-articular Bee Venom Injection on Meniscal Injury : Four Cases Report

    김동은 | 유덕선 | Seung-ryong Yeom and 2other persons | 2010, 20(1) | pp.219~230 | number of Cited : 11
    Abstract
    According to previous reports, intra-articular bee venom injection is very effective for synovitis, intra-articular lesions. In this article, we report 4 cases of well-treated meniscal tear with intra-articular bee venom injection. We used intra-articular bee venom injection on meniscal tear diagnosed by MR imaging and prescribed herbal medication, physiotherapy if necessary. Outcomes were measured by Visual Analogue Scale(VAS) and Lysholm Knee Scoring Scale. Patients who are treated by intra-articular bee venom injection had a significant effect on the pain reduction, improved range of motion and knee function. Further well-designed, controlled studies and more cases are needed to define the effect of intra-articular bee venom injection on knee.