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2015, Vol.25, No.2

  • 1.

    Antibacterial Effect of Haedokgeumhwa-san against Methicillin-Resistant Staphylococcus aureus

    SONG YUNG SUN | 이하일 | Sukyung Lee and 1other persons | 2015, 25(2) | pp.1~13 | number of Cited : 1
    Abstract
    ObjectivesMethicillin-Resistant Staphylococcus aureus (MRSA) is a human pathogen and a major cause of hospital-acquired infections. New antibacterial agents that have not been compromised by bacterial resistance are needed to treat MRSA-related infections. In this study, we investigated the antimicrobial activity ofethanol extract of Haedokgeumhwa-san (HGH) which prescription is composed of korean medicine against MRSA. MethodsThe antibacterial activity of HGH extract was evaluated against MRSA strains by using the Disc diffusion method, broth microdilution method (minimal inhibitory concentration; MIC), checkerboard dilution test, and time-kill test; its mechanism of action was investigated by bacteriolysis, detergent or ATPase inhibitors. The checkerboard dilution test was used to examined synergistic effect of ampicillin, oxacillin, ciprofloxacin, vancomycin, gentamicin and norfloxacin in combination with HGH ethanol extract. A time-kill assay was performed a survival curve which was obtained by plotting viable colony counts depending on time on bacterial growth. ResultsThe minimum inhibitory concentration (MIC) of ethanol extract (HGH) ranged from 1,000 to 2,000 μg/mL against all the tested bacterial strains, respectively. We are able to confirm that HGH extract has potentially strong antibacterial activity. In the checkerboard dilution test, fractional inhibitory concentration index of HGH in combination with antibiotics indicated synergy or partial synergism against S. aureus. A time-kill study showed that the growth of the tested bacteria was considerably inhibited after 8 hr of treatment with the combination of HGH with selected antibiotics. For measurement of cell membrane permeability, HGH 250~1,000 μg/mL along with concentration of Triton X-100 (TX) and Tris-(hydroxymethyl) aminomethane (Tris) were used. In the other hand, N,N-dicyclohexylcarbodimide (DCCD) and Sodium azide (NaN3) was used as an inhibitor of ATPase. TX, Tris, DCCD and NaN3 cooperation against S. aureus showed synergistic action. Accordingly, antimicrobial activity of HGH was affected by cell membrane and inhibitor of ATPase. ConclusionsThese results suggest that Haedokgeumhwa-san extract has antibacterial activity, and that HGH extract offers a potential as a natural antibiotic against MRSA. (J Korean Med Rehab 2015;25(2):1-13)
  • 2.

    Effects of Bujasasim-tang Ethanol Extract on Oxidative Stress, Inflammation and Osteoarthritic Rat Model

    Minseok Oh | Chang-Hoon Woo | 2015, 25(2) | pp.15~35 | number of Cited : 3
    Abstract
    ObjectivesThis study was performed to investigate the effects of Bujasasim-tang ethanol extract (BST) on oxidative stress, inflammation and osteoarthritic rat model.MethodsTo ensure safety of BST, heavy metal levels were measured and cytotoxicity test was done. In vitro, To evaluate antioxidative effects of BST, total phenolic contents, 1,1-diphenyl-2-picryl-hydrazyl (DPPH), 2,2’–azino–bis-(3-ethylbenzothiazoline-6-sulfonic acid)(ABTS) scavenging activity, reactive oxygen species (ROS) levels were measured. Also, to evaluate anti-inflammatory effects of BST treated group, total nitric oxide (NO) and pro-inflammatory cytokines (IL-1β, IL-6, TNF-α) levels were measured in lipopolysaccharide(LPS)-stimulated RAW 264.7 cells. In vivo, We injected MIA 50 μl (60 mg/ml) into knee joints of rats to induce osteoarthritis. Rats were divided into total 3 groups (normal, control, BST treated group, each n=7). Normal group was not treated at all without inducing osteoarthritis and taken normal diet. Control group was induced osteoarthritis by MIA and taken with 2 ml of distilled water once a day for 4 weeks. BST treated group was induced osteoarthritis by MIA and taken BST 2 ml (200 mg/kg/mouse) once a day for 4 weeks. We evaluated dynamic weight bearing with the Incapacitance Test Meter. At the end of experiment, the rats were sacrificed to observe the functions of liver and kidney, changes of WBC, neutrophil, lymphocyte, monocyte levels in blood, to evaluate the levels of pro-inflammatory cytokines, tissue inhibitor of metallopreteinases-1 (TIMP-1), matrix metalloproteinase-9 (MMP-9), prostaglandin E2 (PGE2), leukotriene B4 (LTB4) within serum. We observed change of articular structures by Hematoxylin & Eosin (H&E), safranin-O staining method and measured amount of cartilage by micro CT-arthrography. Statistical analysis was done by unpaired student’s t-test with significance level at p<0.05 in SPSS 11.0 for windows.Results1. Safety of the BST was identified. 2. AST, ALT, BUN, creatinine levels of BST treated group were within normal limit. In vitro, 1. DPPH and ABTS free radical scavenging activities of BST showed dose-dependent increase. 2. ROS production were significantly decreased. 3. Total nitric oxide (NO) and IL-1β production were decreased. 4. IL-6 and TNF-α production were significantly decreased. In vivo, 1. Weight bearing ability was significantly increased. 2. WBC, neutrophil, lymphocyte, monocyte levels in blood were decreased. 3. IL-1β and TNF-α levels in serum were significantly decreased. and the IL-6 level was decreased. 4. TIMP-1, MMP-9, LTB4, PGE2 levels in serum were significantly decreased. 5. Cartilage volume of BST treated group was significantly increased. Also changes of cartilage, synovial membrane, fibrous tissue were suppressed.ConclusionsThe results obtained in this study Bujasasim-tang have effects of anti-oxidative, antiinflammatory, relieve pain and protection of cartilage. Therefore we expect that Bujasasim-tang is effective treatment for osteoarthritis. (J Korean Med Rehab 2015;25(2):15-35)
  • 3.

    Effects of Danggwisayeok-tang (Dangguisinitang) on MIA-Induced Osteoarthritis Rats

    Hee Duk An | Yang Doo Hwa | Chang-Hoon Woo and 1other persons | 2015, 25(2) | pp.37~50 | number of Cited : 4
    Abstract
    ObjectivesThe purpose of this study was to know the effects of Danggwisayeok-tang (Dangguisinitang) extract (DGSYT) on monosodium iodoacetate (MIA)-induced rat osteoarthritis.MethodsFor this purpose, rats were divided into 5 groups. Normal group was not injected with MIA and orally administered any medication. Control group was injected with MIA and not orally administered any medication. DGSYT100 group was injected with MIA and orally administered 100 mg/kg of DGSYT. DGSYT300 group was injected with MIA and orally administered 300 mg/kg of DGSYT. JoinsT group was injected with MIA and orally administered 20 mg/kg of Joins tablet. DGSYT100 and DGSYT300 groups were orally administered DGSYT during a week before and 3 weeks after based on the day MIA injected. The changes of hepatotoxicity, nephrotoxicity, relative hind paw weight distribution, cytokine in serum, cytokine messenger ribonucleic acid (mRNA) in joint tissue and histopathological observation (Hematoxylin & Eosin and Safranin-O staining) were measured.ResultsAlanine aminotransferase (ALT) levels of DGSYT100, DGSYT300 and JoinsT groups were increased significantly, but these results were within normal range. Aspartate aminotransferase (AST) and creatinine levels of all groups were not changed significantly. In the change of relative hind paw weight distribution, DGSYT300 and JoinsT groups were decreased significantly 14 and 21 days after MIA injected. Interleukin-1β (IL-1β) and Interleukin-6 (IL-6), Leukotriene B4 and Osteocalcin levels of DGSYT300 and JoinsT groups were decreased significantly. In measurement of IL-1β and nitric oxide synthase-Ⅱ mRNA relative quantitative of control, DGSYT100, DGSYT300 and JoinsT groups were decreased significantly. In measurement of TNF-α, IL-6 and Cyclooxygenase-2 mRNA relative quantitative of control, DGSYT300 and JoinsT groups was decreased significantly. In histopathological observation of knee, synovial tissue, cartilage and proteoglycan of DGSYT100, DGSYT300 and JoinsT were well preserved compared with control group.ConclusionsAccording to the results, DGSYT has anti-inflammation and pain relief effects. So it should be suppressed progression of arthritis in MIA-induced osteoarthritis rat. (J Korean Med Rehab 2015;25(2):37-50)
  • 4.

    Effects of Gyejigabuja-tang on MIA-induced Osteoarthritis in Rats

    Chang-Hoon Woo | 원제훈 | 2015, 25(2) | pp.51~64 | number of Cited : 6
    Abstract
    ObjectivesThis study was carried out to investigate the effects of Gyejigabuja-tang extracts on the Monosodium iodoacetate (MIA) induced osteoarthritis in rats.MethodsOsteoarthritis was induced by injection of MIA into knee joint cavity of rats. Rats are divided into 4 groups (normal, control, positive comparison group, GBT group, each n=5). Normal group was injected by normal saline into knee joint cavity only. Control group was induced for osteoarthritis by MIA and oral medicated with distilled water. Positive comparison group was injected with MIA and taken Joins tablet 25 mg/kg. GBT group was injected with MIA and taken Gyejigabuja-tang extracts 300 mg/kg. Positive comparison group and GBT group were oral medicated for each substance once a day for 4 weeks. ALT, AST and creatinine were evaluated for hepatotoxicity and nephrotoxicity. Hind paw weight bearing ability was examined and inflammatory cytokines (IL-1β, IL-6, TNF-α), PGE2, LTB4, osteocalcin and deoxypyridinoline (DPD) within serum were analysed. Knee joint structures were observed by Hematoxylin & Eosin (H&E), Safranin-O staining method.Results1. Function of liver and kidney was not affected. 2. Hind paw weight bearing ability was significantly improved. 3. IL-1β, IL-6 and TNF-α in experimental group were significantly decreased compared with control group. 4. PGE2, LTB4, Osteocalcin and DPD in experimental group were decreased compared with control group. 5. In histopathologic observation, injury on synovial membrane and cartilage of experimental group was lesser than control group (H&E, Safranin-O staining).ConclusionsBased on these results, it can be suggested that Gyejigabuja-tang has anti-inflammation effects on the MIA-induced osteoarthritis in rats. (J Korean Med Rehab 2015;25(2):51-64)
  • 5.

    Identification of Novel Standard Compounds for Standardization of Sinbaro3 Pharmacopuncture

    Lee In Hee | 이진호 | 이재웅 and 2other persons | 2015, 25(2) | pp.65~72 | number of Cited : 3
    Abstract
    ObjectivesTo investigate and validate potential standard compounds for standardization of Sinbaro3 pharmacopuncture prepared at OO Hospital of Korean Medicine.MethodsSinbaro3 pharmacopuncture was prepared by extraction, purification and hydrolysis of Harpagophytum procumbens, and various potential standard compounds were quantified through HPLC-UV and HPLC-MS analysis. Validation was examined by assessing specificity, linearity, precision, and accuracy.ResultsThe retention time of harpagide and cinnamic acid were 15.2 min and 28.2 min, respectively, and both showed good linearity in analysis by concentration at 0.9999 and 0.9998, respectively. Intra-day variation of precision was 0.0015~0.0045% and 0.0058~ 0.1629%, while inter-day variation of precision was 0.0011~0.0243% and 0.0098~0.1629%,and that of accuracy was 99.53~99.89% and 99.50~99.91%, respectively.ConclusionsHarpagide and cinnamic acid, which are hydrolyzates of harpagoside within Sinbaro3 pharmacopuncture, were both validated using HPLC-MS and HPLC-UV analysis, and Sinbaro3 pharmacopuncture contained 78.41 ug/ml harpagide, and 2.05 ug/ml cinnamic acid. (J Korean Med Rehab 2015;25(2):65-72)
  • 6.

    Single-dose Intramuscular Toxicity Studies of Shinbaro3 Pharmacopunture in Sprague-Dawley Rats and Beagle Dogs

    김민정 | 이진호 | Lee In Hee and 2other persons | 2015, 25(2) | pp.73~80 | number of Cited : 4
    Abstract
    ObjectivesTo assess the safety of Shinbaro3 Pharmacopuncture by analyzing the potential single-dose intramuscular toxicity of Shinbaro3 Pharmacopuncture at various dose levels in SD (Spraque-Dawley) rats and Beagle dogs.MethodsFor evaluation of single-dose intramuscular toxicity of Shinbaro3 Pharmacopuncture, 40 SD rats (20 male and 20 famale) and 4 Beagle dogs (2 male and 2 female) were used. The rats were divided in four groups of 10 each, and treated intramuscularly with Shinbaro3 Pharmacopuncture at doses of 0.3, 0.6 and 1.2 mg/kg in distilled water, and distilled water as a vehicle control group, respectively. The Beagle dogs were divided into two groups of 2 each, and treated intramuscularly with Shinbaro3 Pharmacopuncture at doses of 0.15, and 0.3 mg/kg in distilled water, respectively, and signs of toxicity were observed. After a wash-out period of 3 days, the procedure was repeated with Shinbaro3 Pharmacopuncture at doses of 0.6, and 1.2 mg/kg in distilled water, respectively. Mortality, body weight changes, and necropsy findings were examined during the study period.ResultsThere were no mortalities in either the SD rats or Beagle dogs. There were also no significant differences in adverse effects, body weight, or necropsy findings between the Shinbaro3 Pharmacopuncture and control groups.ConclusionsThere results suggest that the lethal dose 50 (LD50) and approximate lethal dose (ALD) value of the test substance Shinbaro3 Pharmacopuncture are higher than 1.2 mg/kg in SD rats and Beagle dogs. (J Korean Med Rehab 2015;25(2):73-80)
  • 7.

    Analysis of the Research Trends of Pelvic Malposition in Korean Clinical Research

    강준혁 | 박재현 | 남수현 and 2other persons | 2015, 25(2) | pp.81~88 | number of Cited : 0
    Abstract
    ObjectivesThe purpose of this review was to analyze the research trends in clinical research related to pelvic malposition published in Korean medicine journals.MethodsWe searched articles in Korean databases (OASIS, NDSL, RISS, and KTKP), and sorted the articles by publishing date, pelvic malposition type, field of study, and measurement index.Results1. 25 original articles and 9 case report articles were reviewed. 2. In recent years, this topic has been studied more frequently, with an increasing number of original articles published. 3. 16 articles analyzed pelvic malposition type. And half of the articles focused on ilium. 4. The original articles have figured out the correlation between pelvic malposition measurement indices and other measurement indices or diseases. 5. Treatment tools, such as chuna therapy, the mckenzie method, devices for correcting malposition, acupuncture were used in the case report articles. 6. 29 measurement indices, such as Ferguson’s angle, Ilium shadow measurement, and Iliac height difference were used.ConclusionsAccording to the literature, pelvic malposition is related to other diseases and measurement indices, and manual medicine on pelvic malposition can be effective. However, due to the lack of sufficient empirical evidence from medical articles to support this, further clinical research should be conducted. (J Korean Med Rehab 2015;25(2): 81-88)
  • 8.

    Trends of Chuna Manual Therapy on Traffic Accident in Korea from 2005 to 2014

    Youn-Seok Ko | 전용태 | 박상훈 and 2other persons | 2015, 25(2) | pp.89~96 | number of Cited : 7
    Abstract
    ObjectivesThis study is to investigate domestic trends of chuna manual therapy on traffic accident for recent 10 years.MethodsWe searched the studies on chuna manual therapy for traffic accident in 6 Korean web databases. Consequently, 17 research papers were founded. We analyzed these papers according to their published year, the titles of journal, the type of study, the number of cases, the sites of injury, assessment scales of study, and ethics of research.Results17 papers were published since 2005. The studies on chuna manual therapy about traffic accident were mainly published in the journal of korean society of chuna manual medicine for spine & nerves and the journal of korean medicine rehabilitation. All papers were clinical research include 2 case series, 2 non randomized controlled trials (NRCTs), 13 randomized controlled trials (RCTs). The most frequently occured symptom was neck pain. In assessment scales, visual analog scale (VAS) was mainly used. All clinical studies were not mentioned about approval of institutional review board (IRB).ConclusionsIn this study, we analyzed the trends of chuna manual therapy on traffic accident in Korea from 2005 to 2014. In reviewing published papers, we found several weak points in methods of research and quality of study protocol. It is needed to adjust these problems for development of future researches. (J Korean Med Rehab 2015;25(2): 89-96)
  • 9.

    Acupuncture Treatment of Plantar Fasciitis: A Literature Review

    Lee Jung-han | 고낙용 | 김창곤 and 1other persons | 2015, 25(2) | pp.97~110 | number of Cited : 2
    Abstract
    ObjectivesPlantar fasciitis is one of the most common causes of heel pain. Plantar fasciitis can be managed with acupuncture, but the evidence for its effectiveness is uncertain. The aim of this review was to assess the effectiveness of acupuncture for plantar fasciitis.MethodsI searched specific Korean and foreign electronic databases (KCI, RISS, NDSL, OASIS, KTKP, National Assembly Library, KMbase, PubMed, The Cochrane Library and China National Knowledge Infrastructure). The key search terms were ‘heel pain’, ‘plantar fasciitis’ and ‘acupuncture’. Twenty-seven trials were included; eleven case reports, fourteenrandomized controlled trials (RCTs) and two non-randomized controlled trials (NRCTs).ResultsTwenty-seven studies reported that acupuncture treatment reduced plantar fasciitis pain. However, the evidence provided by the case reports was regarded as weak because the methodological quality was poor, and the placebo effect of acupuncture was not accounted for in the RCTs and NRCTs. Overall, the methodological quality of the RCTs and NRCTs was weak.ConclusionsThere is some evidence for the effectiveness of acupuncture for plantar fasciitis. However, in order to reinforce the evidence for acupuncture’s effectiveness, additional placebo-controlled trials with well-designed methodologies are required. (J Korean Med Rehab 2015;25(2):97-110)
  • 10.

    A Study of Bi-Jeung in the Mid-Chosun Dynasty: Based on the Seungjeongwon Ilgi

    Chung, Seok Hee | 조우영 | 정재영 | 2015, 25(2) | pp.111~118 | number of Cited : 0
    Abstract
    ObjectivesThrough the clinical records of Seungjeongwon Ilgi, we reviewed the usage of Bi-Jeung to know the concept of the word and studied therapeutic strategies for managing Bi-Jeung.MethodsWe investigated the clinical records of the mid-Chosun dynasty containing the key word “Bi” from electronic database (Seungjeongwon Ilgi).ResultsOf 4,039 records, 249 articles thought to have medicinal value were lastly selected. We subdivided the cases into 13 categories according to time, the connection of contents and the change of associated symptoms. “Bi” was not used alone but used in combination with body parts or other symptoms. Etiological causes of “Bi” involved dampness, phlegm, fire, heat and qi disorders. We suggested that “Bi” of the mid-Chosun dynasty meant a symptom group mainly of sensory impairment and additionally pain or motor disturbance. Among the 22 herbal medicine formulas used, 15 were based on internal medical pattern identifications and 7 were symptomatic treatments. Acupuncture and moxibustion therapy were primarily applied to adjacent acupoints. In addition, External therapies were used together, such as washing therapy, plaster therapy, cupping therapy and thermotherapy.Conclusions“Bi” principally indicated sensory impairment on limbs and the main etiological cause was considered to be dampness. Herbal medicine, acupuncture, moxibustion and external therapies were used to cure Bi-Jeung. (J Korean Med Rehab 2015;25(2):111-118)
  • 11.

    The Retrospective Medical Charts Review of 459 Neck Pain Inpatients in Korean Medicine Hospital

    Minseok Oh | 허건 | 2015, 25(2) | pp.119~134 | number of Cited : 0
    Abstract
    ObjectivesThe purpose of this study was to investigate the characteristics of inpatients who were admitted to Korean medicine hospital due to neck pain.MethodsFour hundred fifty nine neck pain patients who were admitted to Cheonan Korean Medicine Hospital, Dae-jeon University from 1st, January, 2013 to 31th, December, 2013 were retrospectively reviewed according to medical charts.ResultsIn this study, people in their 30s, females, within 0~2 weeks after onset, motivated by traffic accident, diagnosed with neck sprain, with no medical history related to neck pain, underwent outpatient treatment at medical institutions, took the highest percentage from each category of patients who admitted to Korean Medicine Hospital due to neck pain. In most (78.77%) of the patients, symptoms were more than improved.ConclusionsNeck pain inpatients in Korean medicine hospital, it is difficult to find tendency. This study suggests the characteristics of neck pain inpatients who were hospitalized in Koean medicine hospital. (J Korean Med Rehab 2015;25(2):119-134)
  • 12.

    Characteristics of 601 Low Back Pain Patients: A Korean Medicine Hospital Experience, Retrospective Chart Review

    Minseok Oh | 남대진 | 2015, 25(2) | pp.135~153 | number of Cited : 2
    Abstract
    ObjectivesThe purpose of this study was to investigate the characteristics of inpatients who were admitted to Korean medicine hospital due to low back pain.MethodsThe current study was designed as a retrospective chart review to investigate descriptive characteristics of LBP patients. The clinical records of 601 patients who were hospitalized for treatment of LBP in Cheonan Korean Medicine Hospital, Daejeon University from 1st, January, 2013 to 31th, December, 2013 were analyzed.Results1. Most frequently given diagnosis was sprain and strain of lumbar (45.93%). 2. Female outnumbered male patients in all disease groups except fracture of lumbar spine. 3. In distribution according to age, sprain and strain of lumbar, HNP of L-spine and lumbago with sciatica were most frequent at 30s, fracture of lumbar spine was most frequent at 50s and spinal stenosis was most frequent at 70s. 4. The most frequently motive for low back pain was traffic accident (35.4%) 5. Patients with no related medical history were 76.95% 6. 0~1week interval between onset and visit to Korean Medicine Hospital was most frequent in all disease groups. 7. 50.85% of patients went through treatment at medical institutions before the admitting to Korean Medicine Hospital. 8. The average admission days of female was higher than male’s. And age goes up, average duration of admission was longer. 9. In most (74.59%) of the patients, symptoms were more than improved. 10. Most frequently prescribed examination was X-ray (65.13%). 11. Most frequently prescribed herb medicine was whal-lak-tang (Huoluo-tang).ConclusionsIn most (74.59%) of the patients, symptoms were more than improved, especially in sprain and strain of lumbar and lumbago with sciatica. But Patients with a local hospital statistic is not be representative of the incidence of the population. In order to obtain more accurate statistics, it is necessary to compare analysis collect statistics from other medical hospitals. (J Korean Med Rehab 2015;25(2):135-153)
  • 13.

    The Retrospective Review of 410 Shoulder Pain Inpatients in Korean Medicine Hospital

    Minseok Oh | 이재은 | 2015, 25(2) | pp.155~173 | number of Cited : 2
    Abstract
    ObjectivesThe purpose of this study is to investigate the characteristics of inpatients who were admitted to Korean medicine hospital due to shoulder pain.MethodsCharacteristics of four hundred ten shoulder pain inpatients of single institution from 2011 to 2013 were retrospectively reviewed through medical charts.ResultsPatients showed different characteristics in sex, age, motives, interval between onset and admission day, first occurrence or not, related medical history before admission, usage of west medication, admission days, treatment results, radiological examinations by shoulder pain disease groups. Accordingly, Korean medical treatment such as acupuncture, moxibustion, external treatment, cupping therapy, physiotherapy, herb-medication varied with the characteristics of shoulder pain disease groups.ConclusionsThrough retrospective medical charts review, characteristics of 410 single institution shoulder pain inpatients showed distinctive features and versatile Korean medicine treatments by disease groups. It is expected that this study would accelerate multi-institutional and large scale characteristic review of shoulder pain patients, which would raise reconsideration and expand boundary of Korean medicine. (J Korean Med Rehab 2015;25(2):155-173)
  • 14.

    A Case Report of Neck Pain Patient with Klippel-Feil Syndrome by Cervical Manipulation Treatment

    금동호 | 이종하 | 권정국 | 2015, 25(2) | pp.175~180 | number of Cited : 0
    Abstract
    The Klippel-Feil Syndrome (KFS) is characterized by congenital fusion of two or more vertebrae with hypermobile normal segment. According to this, a patient with KFS can be at risk of severe neurological symptoms after manipulation treatment. We had a KFS patient who suffered from neck pain and limited range of motion at cervical after manipulation treatment. The patient, 49-year-old woman was diagnosed as KFS through Cervical X-ray and MRI. The patient was treated by acupuncture therapy and SCENAR therapy. We measured neck pain by visual analog scale (VAS) and neck disability index (NDI) and checked range of motion at cervical before and after the treatments. After 8 times treatments, the patient’s pain decreased and the range of motion increased. From this case, we can recognize the risk of Chuna manipulation treatment for KFS patient. So, we suggest that radiological examination is needed before cervical Chuna manipulation treatment to avoid adverse reactions. (J Korean Med Rehab 2015;25(2):175-180)
  • 15.

    A Clinical Case Study of Operation-delayed Cauda Equina Syndrome Patient Improved by Korean Traditional Treatment

    Suhyeon Jeong | 정해창 | 2015, 25(2) | pp.181~187 | number of Cited : 2
    Abstract
    ObjectivesThe objective of this study is to report clinical effect of korean traditional treatments for Operation-delayed Cauda Equina Syndrome patient.MethodsThe patient was treated by korean traditional treatments including acupuncture, physical treatment, herbal medication. The improvement of the clinical symptoms was observed by Modified Visual analog scale (Modified VAS), SSCES (Scoring System for Cauda Equina Syndrome), function of urination and function of defecation.ResultsAfter treatments, Modified VAS, SSCES, function of urination and function of defecation were improved in this case.ConclusionsOn the basis of these results, we suggest that korean traditional treatment might be an effective method to improve the clinical symptoms of Operation-delayed Cauda Equina Syndrome patient. (J Korean Med Rehab 2015;25(2):181-187)
  • 16.

    The Clinical Study of Oriental Medicine on Spontaneous Osteonecrosis of the Knee

    이상욱 | 양재철 | 옥소윤 and 2other persons | 2015, 25(2) | pp.189~196 | number of Cited : 0
    Abstract
    Objectives The purpose of this study was to report the effect of Oriental medicine on spontaneous osteonecrosis of the knee.MethodsPatients received Oriental treatment such as Bee-Venom therapy and acupuncture & moxibustion. The improvement of the pain intensity and recovery of gait was observed.ResultsDuring five weeks of treatment, patient's knee pain and gait disturbance were improved.ConclusionsIn this case, Oriental treatment on spontaneous osteonecrosis was effective to reduce pain and recover gait. (J Korean Med Rehab 2015;25(2):189-196)
  • 17.

    Deep Vein Thrombosis after Total Knee Replacement in a Patient undergoing Korean Medical Rehabilitation

    Lee Jung-han | 김창곤 | 고낙용 and 1other persons | 2015, 25(2) | pp.197~203 | number of Cited : 2
    Abstract
    ObjectivesThe objective of this study is to report the deep vein thrombosis (DVT) after total knee replacement (TKR) in a patient undergoing Korean medical rehabilitation.MethodsA female patient who had total knee replacement (TKR) was treated by Korean medical rehabilitation with protocol. After fifteen days treatment, deep vein thrombosis (DVT) was suspected. Therefore, CT venography was performed.ResultsAfter Korean medical rehabilitation, pain was decreased. But also occurred deep vein thrombosis (DVT) as a complication.ConclusionsWe present a case of deep vein thrombosis (DVT) after total knee replacement (TKR) in a patient undergoing Korean medical rehabilitation. There is a limit that this study hasn’t sufficient number of cases. Further studies will be needed. (J Korean Med Rehab 2015;25(2):197-203)