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2017, Vol.27, No.1

  • 1.

    Effects of Bangkibokryeong-tang (Fangjifuling-tang) on the Reduction of Blood Glucose and Body Fat in High Fat Diet Induced Obese Mice

    유형진 | 이종하 | Sukyung Lee and 1other persons | 2017, 27(1) | pp.1~17 | number of Cited : 1
    Abstract
    ObjectivesThis study aimed to investigate the effect of Bangkibokryeong-tang (BBT, Fangjifuling-tang) on blood glucose and body fat in high-fat diet-induced obese mice.MethodsThe experimental animals were divided into five groups- normal diet-fed control (ND), high-fat diet-fed control (HFD), HFD+BBT 75, HFD+BBT 150, and HFD+olistat as a positive drug control group. Markers of obesity, such as body weight, organ weight, diet ef-ficiency, and serum levels of total cholesterol, triglycerides, lipid content, leptin, adipo-nectin, glutamic oxaloacetic transaminase (GOT)/glutamic pyruvic transferase (GPT)/lactate dehydrogenase (LDH), blood glucose, and insulin, were measured. Furthermore, results of the oral glucose tolerance test and α-glucosidase inhibition activity were examined in obese mice.ResultsMice treated with BBT demonstrate lower body and organ weight, and reduced weight gain and food efficiency than that in the HFD-only control group. In addition, BBT decreased lipid accumulation in the liver and the levels of enzymes such as GOT, GPT, and LDH in the serum. Furthermore, the levels of triglycerides, total cholesterol, low density lip-oprotein (LDL), and leptin were decreased in the serum but the levels of high density lip-oprotein (HDL) and adiponectin were increased in the BBT-treated group compared with the control group. The BBT-treated group also demonstrated decreased blood glucose and in-sulin concentrations induced by feeding on a high-fat diet and improved glucose tolerance.ConclusionsBased on the results above, BBT may reduce body fat and hyperglycemia in HFD-induced obesity. This suggests that BBT may be clinically useful in the treatment of obesity. (J Korean Med Rehabil 2017;27(1):1-17)
  • 2.

    Comparison of Index Compound Content and Anti-inflammatory Activity of Eucommiae Cortex by Various Drying Methods

    도호정 | 이진호 | 하인혁 and 5other persons | 2017, 27(1) | pp.19~25 | number of Cited : 3
    Abstract
    ObjectivesEucommiae cortex is one of the frequently used herbs for musculoskeletal disorders, with well-known anti-inflammatory effect. Meanwhile, powdered form of herbal drugs is more advantageous than decoction form, in that storing and taking is more convenient. Thus, the authors aimed to investigate whether the drying method affects the index compound level and anti-inflammatory effect of eucommiae cortex water extract.MethodsEucommiae cortex was extracted in distilled water at 100oC for 3 hours, filtered, and then evaporated under vacuum. One half of the sample was freeze-dried at −80oC. Another half of the sample was added with dextrin and then spray-dried at 180oC. To as-sess the possible change in index compound content, pinoresinol diglucoside was selected as the index marker. The content level of the index compound in various extract sample was quantified through high performance liquid chromatography. In addition, iNOS assay in LPS-induced RAW 264.7 cells was adopted to determine the anti-inflammatory effect of various extract samples. Furthermore, MTT assay was performed to confirm that the result of iNOS assay was not due to cytotoxicity.ResultsThere was no significance difference in index compound content between ex-tract samples obtained through two different drying methods. Anti-inflammatory activity of extract samples were similar at the matching concentration, regardless of the drying methods. Extract samples did not show any significant cytotoxicity.ConclusionsExtract samples of eucommiae cortex were obtained through freeze-drying and spray-drying. Neither change in index compound content nor difference in anti-in-flammatory activity was observed between drying methods. (J Korean Med Rehabil 2017;27(1):19-25)
  • 3.

    Interventions of Korean Medicine for Hip Pain: A Literature Review of Case Studies

    박상철 | Sung Soo Hyun | 안뜰에봄 and 3other persons | 2017, 27(1) | pp.27~35 | number of Cited : 1
    Abstract
    ObjectivesThis study aimed to review case studies on interventions of Korean medicine for hip pain.MethodsWe searched seven electronic databases for relevant studies up to Oct 2016. Case studies of Korean medicine interventions for hip pain were included and analysed.Results15 case studies were included (Korean databases; n=15) and Total number of patients was 17 cases. A total of 13 types of interventions were reported, of which acu-puncture (93.3%), herbal medicine (80.0%) and pharmacopuncture (40.0%) were the most frequently used. GB30 (66.7%), LR3 (41.7%), BL36 (33.3%) and ST31 (33.3%) were used in at least 4 papers. Cheongpa-jeon (25.0%) and symptom change (46.7%) were most fre-quently used in herbal medicine and outcome measure respectively.ConclusionsClinical studies, especially double-blinded randomized controlled trials, of Korean medicine interventions for hip pain must be conducted to obtain definite conclusions. (J Korean Med Rehabil 2017;27(1):27-35)
  • 4.

    Effect of Acupuncture Combined with Wooden Neck Pillow Self-exercise Program on Cervical Curvature Measurement Methods and Deep Flexor Muscle Strength

    권정국 | Keum Dong-ho | 2017, 27(1) | pp.37~51 | number of Cited : 0
    Abstract
    ObjectivesThis study was designed to identify the effect of acupuncture combined with wooden neck pillow self-exercise program (WSP). Methods25 eligible subjects with chronic neck pain were recruited from September 2015 to August 2016. Subjects were treated by acupuncture twice a week for 4 weeks, al-so were educated WSP and exercised every day for 4 weeks. They were assessed using PI-NRS, NDI and the maximum muscle strength of deep cervical flexor muscles (DCF) be-fore and after treatment. Also the Cobb’s angle (C1-C7), Ishihara index, Park method were assessed for evaluating the radiographical changes. Variables were compared using paired t-test. And correlates analysis was used for analyzing relationship between differentials in the maximum muscle strength of DCF and differentials in cervical spine curvature measure-ment methods. ResultsAmong the 25 subjects, 4 subjects were lost to follow-up or excluded in accord-ance with the criteria. Significant differences on NRS, NDI and the maximum muscle strength of DCF were seen after treatment (p<0.001). In radiological finding, cervical spine curvature measurement methods were significantly increased (p<0.001, p<0.05, p<0.05). Differentials in the maximum muscle strength of DCF significantly correlates to dif-ferentials in Ishihara index (R=0.479, p<0.05).ConclusionsAcupuncture combined with WSP may decrease neck pain intensity and associated disability, and also increase the muscle strength of DCF and cervical lordosis, in patients with chronic neck pain. Especially, Improving the muscle strength of DCF has a re-lationship with improving Ishihara index. However, due to the design of this study, this treat-ment can not be compared with other treatments. Future randomized project should be needed. (J Korean Med Rehabil 2017;27(1):37-51)
  • 5.

    A Study on Safety Assessment and VAS Change Observation Before and After Non-toxic Bee Venom Treatment in Pain Patients Using Questionnaire: Retrospective Chart Review

    황윤경 | 정택근 | Cho Sungwoo and 1other persons | 2017, 27(1) | pp.53~65 | number of Cited : 1
    Abstract
    ObjectivesThe purpose of this study is to evaluate the safety of Non-toxic bee venom (BV) and observe VAS change before and after Non-toxic BV treatment in pain patients.MethodsWe surveyed the clinical practitioners who treated with Non-toxic BV in pain patients who visited the Korean medical clinic. The questionnaire survey was conducted for clinical practitioners who agreed to participate after hearing the explanation for the purpose and characteristics of the questionnaire. Patients in the questionnaires were reviewed based on their medical records from July 1, 2016 to October 28, 2016.ResultsWe received 445 cases and selected 403 cases finally. 2 cases, however, were not able to continue treatment for 3 weeks and were eliminated. Depending on when the pain occurred, we divided the 401 cases into three groups (Acute, Subacute, Chronic group). In all groups, VAS scores were significantly decreased after treatment. Adverse re-actions following Non-toxic BV treatment had occurred was 16 cases (3.60%). Except for 3 cases with hives, most of adverse reactions were mild or moderate and were not in need of extra treatment. The total safety of treatment for 3 weeks was mostly safe. The number of cases discontinued treatment was 42 cases (9.44%). Most of these cases, treatment was stopped for personal reason unrelated to the Non-toxic BV treatment.ConclusionsThese results suggest that the Non-toxic BV treatment has no serious ad-verse reactions and is a relatively safe treatment. Further studies are needed to prove the efficacy and clinical safety of Non-toxic BV treatment. (J Korean Med Rehabil 2017; 27(1):53-65)
  • 6.

    A Case Report of Lumbar Spinal Stenosis Improved with Diarrhea-Inducing Treatment by Gamsui-mal and Korean Medicine Treatment

    남수현 | 김동후 | 최현민 and 2other persons | 2017, 27(1) | pp.67~75 | number of Cited : 7
    Abstract
    The purpose of this study is to report the effectiveness of diarrhea-inducing treatment by Gamsui-mal for lumbar spinal stenosis. During hospitalization four patients with lumbar spinal stenosis were treated with diarrhea-inducing treatment by Gamsui-mal and acupuncture, herbal medicine, moxibustion, cupping treatment, Bee-venom pharmacopuncture. Before treatment, we explained in detail about diarrhea-inducing treatment by Gamsui-mal and pa-tients agreed with treatment. The symptoms appeared in patients of diarrhea, abdominal pain, and vomiting in the treatment process. We evaluated the degree of improvement by vis-ual analogue scale (VAS), oswestry disability index (ODI). After treatment, we found that pain was reduced and patient's symptoms were improved by visual analogue scale (VAS), oswes-try disability index (ODI) score. The results show that diarrhea-inducing treatment by Gamsui-mal was rapidly improving symptoms. Further studies are needed to clarify the effect of diarrhea-inducing treatment by Gamsui-mal. (J Korean Med Rehabil 2017;27(1):67-75)
  • 7.

    Hemifacial Spasm Treated with Acupuncture and Electro-acupuncture in 2 Patients: Case Report

    김성태 | 송민영 | Min Gu Kwon and 2other persons | 2017, 27(1) | pp.77~81 | number of Cited : 1
    Abstract
    Hemifacial spasm is a facial nerve disorder characterized by episodic involuntary facial muscle contraction. In this study, the effect of Acupuncture and Electro- acupuncture ther-apy for two patient with hemifascial spasm were evaluated. Two patients with hemifacial spasm were treated with Acupuncture and Electro-acupuncture and evaluated with Scott's scale and Treatment satisfaction grade. In Case 1, the grade of spasm intensity classified by Scott’s description improved from 3 to 1. In Case 2, the grade improved from 4 to 2. Patients were satisfied with the treatment in both cases. Acupuncture and Electro-acu-puncture seem to be effective in the treatment of hemifacial spasm. (J Korean Med Rehabil 2017;27(1):77-81)
  • 8.

    45 Cases Report of Korean Medicine Rehabilitation after Surgery

    김태령 | 김영준 | Chang-Hoon Woo | 2017, 27(1) | pp.83~89 | number of Cited : 4
    Abstract
    The purpose of this study is to report the effectiveness of Korean Medicine Rehabilitation for postoperative patients. We analyzed electronic medical records of the 45 postoperative patients who were admitted to the department of Korean Medicine Rehabilitation from January 1st, 2014 to November 30th, 2016. And the effect of the treatments was meas-ured with numeric rating scale (NRS). Pain reduced from 10 at the time of admission to 6.49±0.38 (mean±SE) at the time of discharge. And the patients who took medication to relieve pain were not significantly different compared the patients treated Korean Medicine Rehabilitation alone. We can effectively use Korean Medicine Rehabilitation for post-operative pain management. Further studies are needed to prove effect and safety. (J Korean Med Rehabil 2017;27(1):83-89)