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2017, Vol.27, No.4

  • 1.

    The Protective Effects of Dangguibohyul-tang (Dangguibuxuetang) against Disuse Muscle Atrophy in Rats

    Kim Bum Hoi | 2017, 27(4) | pp.1~9 | number of Cited : 2
    Abstract
    ObjectivesOxidative stress, in which antioxidant proteins and scavenger protection are overwhelmed by reactive oxygen species (ROS) production, is recognized as one of central causes of disuse muscle atrophy. In this study, the hypothesis that oral treatment with Dangguibohyul-tang (Dangguibuxuetang) could attenuate immobilization-induced skeletal muscle atrophy was tested. MethodsThe hindlimb immobilization was performed with casting tape to keep the left ankle joint in a fully extended position. The Rats in Dangguibohyul-tang treated group (DGBHT) (n=10) were orally administrated Dangguibohyul-tang water extract, and rats of Control group (n=10) were given with saline only. After 2 weeks of immobilization, the mor-phology of right and left gastrocnemius muscles in both DGBHT and Control groups were assessed by hematoxylin and eosin staining. ResultsDangguibohyul-tang water extract represented the significant protective effects against the reductions of the left gastrocnemius muscles weight and average cross section area to compared with Control group. Moreover, the treatment with Dangguibohyul-tang extract significantly enhanced the Cu/Zn-SOD activities in gastrocnemius muscle com-pared with Control group. ConclusionsThses results suggest that Dangguibohyul-tang has protective effects against immobilization-induced muscle atrophy by increasing the Cu/Zn-SOD activities in gastrocnemius muscle. (J Korean Med Rehabil 2017;27(4):1-9)
  • 2.

    The Domestic Trends of Korean Medical Treatments for Neck Pain Caused by Whiplash Injury

    정성현 | 이현호 | Gi-Eon Lee and 3other persons | 2017, 27(4) | pp.11~19 | number of Cited : 0
    Abstract
    ObjectivesWe attempted to investigate the trends of Korean Medical treatments for neck pain caused by whiplash injury by analyzing domestic clinical studies.MethodsWe searched for studies listed on Korean electronic databases (KTKP, OASIS, RISS, KMbase, NDSL, KCI, and National Assembly Library). Clinical studies were chosen according to the inclusion criteria. Subsequently, we compared and analyzed the data.ResultsThe search yielded 35 studies, of which there were 12 randomized controlled tri-als (RCTs), 15 non-randomized controlled trials (NRCTs), 6 case reports, and 2 before-after studies. Among these, 54.7% of participants were in the acute stage of the damage period. Pharmacopuncture was used the most in main treatment methods. Only 14.3% of studies mentioned approval by an institutional review board (IRB) and only 8.6% of studies consid-ered side effects.ConclusionsThere is some evidence that Korean Medical treatment is effective for neck pain caused by whiplash injury. Since all studies, however, were exposed to the risk of bias. Therefore, future studies of a higher quality are required. (J Korean Med Rehabil 2017;27(4):11-19)
  • 3.

    Literature Review of Manual Therapy for Mononeuropathies of Upper Limb

    김형석 | 신우철 | 전준영 and 8other persons | 2017, 27(4) | pp.21~31 | number of Cited : 1
    Abstract
    ObjectivesThis study aimed to review manual therapies for mononeuropathies of upper limb through domestic and foreign studies designed for human body.MethodsWe searched databases (KMbase, OASIS, RISS, NDSL, KISS, KoreaMed, MEDLINE/Pubmed, CENTRAL, EMBASE) on the 1st to 31th of July 2017 to find related lit-eratures that published after 2000.ResultsTwenty-eight studies were finally included. Of these, 13 articles were published after 2010. Twenty-two studies were clinical trials and 6 were observational studies. Carpal tunnel syndrome were the most researched type of diseases (85.7%). Most frequently used method of manual therapies was neurodynamic mobilization (35.7%). Pain scales and questionnaires were generally employed for evaluation. Significantly effective studies were 72.2% in controlled trials and 90% in the studies without control group.ConclusionsIn this study, we reviewed literatures concerning manual therapies on mon-oneuropathies of upper limb. Further studies are needed on the various diseases of mono-neuropathies of upper limb to retain the evidence for the effectiveness of manual therapies. (J Korean Med Rehabil 2017;27(4):21-31)
  • 4.

    The Effect of Orally Administered Herbal Medicines in Collagen, LPS, CFA Induced Rheumatoid Like Arthritis Animal Model: A Systematic Review of Animal Study Articles Published in Korea after 2008

    원정윤 | Jeon Chaeheun | 송호준 and 4other persons | 2017, 27(4) | pp.33~53 | number of Cited : 2
    Abstract
    ObjectivesThis study was designed to review animal studies about the efficacy of herbal medicine for Rheumatoid arthritis animal model which was published in Korea after 2008. We also systematically investigated the reporting quality of the animal studies. MethodsWe systematically searched original articles in 8 databases since 2008. And manual searching was conducted through 10 Korean medicine journals from 2008. Studies were included if they used animal experimental model(s) with orally administered herbal medicine. Data were extracted regarding animal model, rheumatoid arthritis indicator and detail of intervention. Reporting quality of each study was also assessed by the STARA and ARRIVE guidelines. ResultsNine hundred two articles were screened. Finally, 35 articles were included. 35 studies all showed that the herbal medicine used in the studies has significant effect on alle-viating the macroscopic indicators, hematological indicators, histological indicators, genet-ic indicators, osteological indicator of Rheumatoid Arthritis and others. Species of animals was reported in 100% while ventilation and noise were reported in 0% in STRASA guidelines. Ethical statement was reported in 42.9%, experimental animals and sample size were reported in 24%, 29% and there was no study reporting funding. ConclusionsThese results suggest that herbal medicine might be effective treatment for Rheumatoid Arthritis. It should be improved by clinical studies. And there is a need for studying about efficacy and safety of each specific herbal medicine. And we should im-prove the Reporting quality of the animal studies published in Korea. (J Korean Med Rehabil 2017;27(4):33-53)
  • 5.

    A Comparative Review on Carthmi-Flos Pharmacopuncture Treatment - Focused on Clinical Study

    Soo-Hwan Lee | 윤정원 | kim Sun Jung | 2017, 27(4) | pp.55~65 | number of Cited : 2
    Abstract
    ObjectivesThe purpose of this review is to analyze results of case studies and controlled studies about Carthmi-Flos pharmacopuncture. Based on the review, authors desire to suggest the study model including precise information and evident the effect of Carthmi-Flos pharmacopuncture objectively in treating clinical disorders.MethodsWe search 44 studies about Carthmi-Flos pharmacopuncture from 6 Korean web databases, using words ‘Carthmi-Flos pharmacopuncture’ in Korean alphabet. This study had been conducted throughout 1 month (July, 2017). We selected case studies and controlled trials in investigated 44 thesis, excluding experimental research and thesis not using the Carthmi-Flos pharmacopuncture for major treatment.ResultsWe analyze 13 case reports and 7 controlled trials. As a result, Carthmi-Flos Pharmacopuncture was used mostly in musculoskeletal, neurological diseases. But this can be applied to internal diseases. Disorders reported effectively were carpal tunnel syn-drome, degenerative knee joint arthritis, posterior neck pain, low back pain, radial nerve palsy, shoulder pain, lumbar compression fracture, alopecia areata, chronic daily head-ache, duverney fracture, oligomenorrhea, cervical disc herniation, rheumatoid arthritis and cervical headache.ConclusionsAs we analyzed, Carthmi-Flos pharmacopuncture is specifically effective in musculoskeletal and neurologic diseases. But there are various problems in study design. To design accurately, the study design should include much more specific information. And the result can be more precise by excluding other methods. (J Korean Med Rehabil 2017;27(4):55-65)
  • 6.

    Appraisal of Clinical Practice Guidelines of Temporomandibular Disorders Using AGREE II (Appraisal of Guidelines for Research & Evaluation II)

    윤예지 | 박혜성 | 김형석 and 12other persons | 2017, 27(4) | pp.67~74 | number of Cited : 0
    Abstract
    ObjectivesThis study is aimed to identify and evaluate the already developed clinical practice guidelines (CPGs) of temporomandibular disorders (TMD) and contribute to mak-ing decisions in developing Korean medicine CPG of TMD.MethodsWe searched electronic database and selected CPGs of TMD according to the inclusion and exclusion criteria. Then, we made appraisal of selected CPGs by using AGREE II (Appraisal of Guidelines for Research & Evaluation II).ResultsFour CPGs are included and appraised with AGREE II. Among 6 domains of AGREE II, all CPGs failed to score over 60% in four domains. Only one CPG mentioned acupuncture as an adjunctive treatment for myofascial TMD. ConclusionsIt is difficult to indicate that included CPGs are with sufficient quality to rec-ommend and it appears not to be appropriate to apply these already developed CPGs in Korean medicine clinical fields. Therefore, developing a new Korean medicine clinical prac-tice guideline of TMD is required. (J Korean Med Rehabil 2017;27(4):67-74)
  • 7.

    A Review of Clinical Study on Jungsongouhyul Pharmacopuncture Treatment Published in Korea

    윤정원 | kim Sun Jung | 2017, 27(4) | pp.75~84 | number of Cited : 3
    Abstract
    ObjectivesTo review the case studies and controlled studies about Jungsongouhyul pharmacopuncture treatment. MethodsWe searched 92 studies about Jungsongouhyul pharmacopuncture from 6 Korean web databases, using words ‘Jungsongouhyul’, ‘Jungsongouhyul and pharmaco-puncture’, ‘ouhyulpharmacopuncture’ and ‘ouhyul and pharmacopuncture’ in Korean alphabet. We removed 63 duplicated studies. And we excluded 12 studies by reviewing abstract and the contents of a study.ResultsWe selected 5 case studies and 12 controlled studies, excluding experimental research and study not on humans, not using the Jungsongouhyul pharmacopuncture for major treatment. Jungsongouhyul pharmacopuncture was used mostly in whiplash injury and all studies showed that Jungsongouhyul pharmacopuncture is effective treatment. But we found some lacking parts with study design in most studies.ConclusionsWe found out that Jungsongouhyul pharmacopuncture is effective in vari-ous diseases. But we need to do more well-designed study to increasing reliability of Jungsongouhyul pharmacopuncture treatment. (J Korean Med Rehabil 2017;27(4):75-84)
  • 8.

    Systematic Review on Traditional Chinese Herbal Medicine Treatment for Antibiotic Associated Diarrhea

    CHANG SEJU | Myeong-Jong Lee | Hojun Kim | 2017, 27(4) | pp.85~96 | number of Cited : 0
    Abstract
    ObjectivesTo summarize and evaluate the efficacy of traditional Chinese herbal medi-cine (TCHM) treatment for antibiotic associated diarrhea (AAD). MethodsEight electronic databases were searched from their inception to August 2017. Randomized controlled trials (RCTs) assessing the efficacy of TCHM treatment for AAD were included. The risk of bias was assessed using the Cochrane risk of bias assessment tool. Data analysis was performed using RevMan software version 5.3. ResultsSeventeen RCTs involving 1138 patients with AAD were included for qualitative synthesis. TCHM treatment improved total effective rate (TER). However, the results that TER in experimental group was significantly higher than in control group were different be-tween the included studies. TCHM enema treatment improved TER, but not significantly higher than control group. The most frequently used herbal formulas were Gamiwekwan-jeon, Gamiinsampaedoksan, and Samryungbaekchulsan. The most frequently used TCHMs were Atractylodes macrocephala (Bai Zhu), Dioscorea batatas (Shan Yao). Within the studies documenting the adverse events, no serious adverse events associated with TCHM treatment were observed. ConclusionsEvidence of TCHM treatment efficacy for AAD is encouraging, but not con-clusive, because of the low methodological qualities, diversity of TCHM treatment prescriptions. Further well-designed RCTs with rigorous randomization and blinding meth-od are needed to confirm these results. (J Korean Med Rehabil 2017;27(4):85-96)
  • 9.

    The Exploratory Analysis on the Registry Data of Patients with Low Back Pain Applying Correlation Analysis Method

    박창현 | Park musun | 김형석 and 8other persons | 2017, 27(4) | pp.97~109 | number of Cited : 0
    Abstract
    ObjectivesThe aim of this study is to analyze the patients who have low back pain through registry.MethodsWe registered patients with low back pain who visited department of korean rehabilitation medicine in university hospitals on study. We collected data from 116 sub-jects consisted of 51 inpatients and 65 outpatients and ruled out 8 who didn’t have pattern identification data at the point of inpatient or outpatient visit so we analyzed 108 in total. We used Pearson’s product moment correlation to find correlationship among variables, and analyzed statistical data using Phyton scipy library stats package.ResultsWe set general features, region of the pain, physical examination, ROM, ques-tionnaire results, pattern identification as variables and draw a conclusion by analyzing these variables.ConclusionsRegistry aimed at low back pain patients was established in department of korean rehabilitation medicine of university hospitals and exploratory analysis based on da-ta were made. Through the registry, we expect that more advanced studies will be per-formed; for example, executing research which verifies effectiveness and stability of korean medical treatment or developing tools to fill the gap between pattern identification and dis-ease identification. (J Korean Med Rehabil 2017;27(4):97-109)
  • 10.

    An Integrative Care Model of Clinical Pathway Approach for Acute Pain after Back Surgery: A Protocol for Clinical Trial

    김병준 | Shin, Byung Cheul | Hwang Mansuk and 6other persons | 2017, 27(4) | pp.111~119 | number of Cited : 1
    Abstract
    ObjectivesClinical pathway (CP), is management plans that display goals for patients and have led to improve outcomes for many diseases. In Korea, Interest in Korean medi-cine's stabilization (Clinical pathway, Clinical Practice Guideline) is increasing, But the num-ber of studies is scare. Method and AnalysisThis trials composes nonequivalent control group pre-test-posttest design to conduct clincal pathway trial for the acute pain after back surgery. The subjects were 10 control patients with back surgery, and 10 experimental patients with application of integrative CP. Each group patient will observed 6 weeks. We check vali-dation of CP. Also we compared the patient's status using the pain, function, Quality of life index between the two groups.DiscussionThis trial is the first CP for the acute pain after back surgery using integrative medicine concepts. Aim of this trial is to find the effectiveness and validity of clincal pathway for acute pain after back surgery. (J Korean Med Rehabil 2017;27(4):111-119)
  • 11.

    Study on Correlation between the Gait Analysis Indices and Lumbar X-ray Indicators

    Jonghan Park | 정수현 | 2017, 27(4) | pp.121~130 | number of Cited : 0
    Abstract
    ObjectivesThis study was designed to investigate the correlation between the gait anal-ysis indices and Lumbar X-ray indicators.Methods21 cases of patients who received treatment from October 2013 to February 2017 for abnormal posture were analyzed. Three indicators were measured in the lumbar spine X-ray. These indicators include Ferguson’s angle, Lumbar lordotic angle, L4-5 IVD angle. Gait analysis indices were estimated by Treadmill Gait Analysis system. The data were analyzed to find out correlation between the gait analysis indices and Lumbar X-ray indicators. Spearman correlation was used.ResultsFerguson’s angle and Difference of gait balance of front and rear had a negative linear relationship, but there was no statistical significance. Lumbar lordotic angle and Difference of gait balance of front and rear had a negative linear relationship, but there was no statistical significance. L4-5 IVD angle and Difference of gait balance of right and left had a negative linear relationship, but there was no statistical significance.ConclusionsDifference of gait balance of front and rear had strong level of a negative lin-ear relationship with Ferguson’s angle and Lumbar lordotic angle. (J Korean Med Rehabil 2017;27(4):121-130)
  • 12.

    A Web-based Survey on Clinical Practice Patterns of Korean Medicine Treatment for Traffic Injuries

    박인화 | Hwang Eui-hyoung | Hwang Mansuk and 4other persons | 2017, 27(4) | pp.131~145 | number of Cited : 7
    Abstract
    ObjectivesThe purpose of this study is to understand current status of Korean Medicine treatment practice patterns for traffic injuries by web-based survey.MethodsThe structured questionnaire was distributed by a web based survey to 1,630 potential respondents by email from December 19th in 2016 to February 13th in 2017. All data were statistically analysed. ResultsThe response rate was 79.4%. According to the analysis of the outcome of the survey, 88.0% of the participants felt necessity of the development of Korean medicine clin-ical practice guidelines (CPGs) for traffic injuries. Survey results showed cognitive degree about Korean Medicine CPGs’ necessity, individual Korean medicine treatments and re-quirement for extending insurance coverage for patients with traffic injuries.ConclusionsThis survey study helps to determine current clinical practice patterns of Korea medicine treatments for traffic injuries. These results further anticipate to provide ba-sic data for CPGs for traffic injuries. (J Korean Med Rehabil 2017;27(4):131-145)
  • 13.

    Fire Needling Therapy in Patients with a Vertebral Compression Fracture: A Report of Three Cases

    Tae-Ryeong Kim | 김영준 | Chang-Hoon Woo | 2017, 27(4) | pp.147~154 | number of Cited : 2
    Abstract
    The purpose of this study is to report the effectiveness of Fire needling therapy in patients with a vertebral compression fracture. Three patients with a acute vertebral compression fracture were treated using Fire needling therapy. To evaluate the effectiveness of Fire nee-dling therapy, we checked Numerical rating scale on a daily and Oswestry disability index on admission and discharge. Numerical rating scale decreased as the number of Fire nee-dling therapy increased. Oswestry disability index on discharge improved compared to admission. The limitation of this study is the insufficient number of cases and outcome measurements. Further studies are needed to prove effect and safety. (J Korean Med Rehabil 2017;27(4):147-154)
  • 14.

    A Case Report of Bee Venom Pharmacopuncture Therapy at Facet Joint for the Two Patients with Herniated Intervertebral Disc of Lumbar Spine

    옥소윤 | 손수아 | Yujin Lee and 1other persons | 2017, 27(4) | pp.155~161 | number of Cited : 1
    Abstract
    The purpose of this study is to research and report the effect of Bee Venom pharmaco-puncture therapy at facet joint for the two patients who was diagnosed as herniated inter-vertebral disc (HIVD) of lumbar spine. Two patients were hospitalized and treated with Complex Korean Medical treatment such as acupuncture, herbal medicine and Essential bee venom (EBV) pharmacopuncture in Dongsuwon hospital of oriental medicine. We measured their pain and function of daily life by numerical rating scale (NRS), straight leg rasing test (SLRT), Roland-morris disability questionnaire (RMDQ). As the result, we found the improvement of gait disturbance, functional disorder, and pain. This study suggested that Bee Venom pharmacopuncture therapy at facet joint is considered to conservative treatment for HIVD of lumbar spine. But further clinical studies are needed to clarify the ef-fect of Bee Venom pharmacopuncture therapy at facet joint for the two patients with HIVD of lumbar spine. (J Korean Med Rehabil 2017;27(4):155-161)
  • 15.

    4 Cases of Patients That Improved from Traffic Accident Which Caused Lumbar Spine Compression Fracture by Complex Korean Medical Admission Treatment: Retrospective Case Study

    홍제락 | 김유종 | 김지수 and 5other persons | 2017, 27(4) | pp.163~170 | number of Cited : 3
    Abstract
    ObjectivesThe objective of this study is to report 4 patients who had vertebral com-pression fracture after traffic accident, that had a complex korean medical admission treatment.MethodsIn this study we collected the data of traffic accident patients that came to re-ceive intense Korean medical treatment, and had compression fracture of the lumbar spine. A total of 4 patients were studied and we compared the Visual Analogue Scale (VAS) score and the Pain-Free Walking Distance (PFWD) at addmission date and 19th day of hospitalization. ResultsAfter receiving an average of 22.25 days of admission treatment, all patients showed a significant decrease in VAS scores and increase in PFWD. The median VAS score at date of admission was 6.5 (VAS 6∼9) and decreased to 3.5 (VAS 3∼5), median PFWD was 37.5 (30∼45) m and increased to 435 (420∼450) m. ConclusionsAfter complex korean medicine admission treatment, 4 patients with verte-bral compression fracture caused by traffic accident showed decrease of pain and increase of walking distance. But there is a need for further studys to be done on treatment methods and evaluation methods. (J Korean Med Rehabil 2017;27(4):163-170)
  • 16.

    A Rehabilitation for Ankle Fracture in Korean Medicine: A Report of 4 Cases

    Ha WonBae | 이종하 | Yoon-seung Lee and 3other persons | 2017, 27(4) | pp.171~184 | number of Cited : 6
    Abstract
    The objective of this study was to propose a rehabilitation protocol for ankle fracture in Korean Medicine and to report its effectiveness. Four patients who had undergone ankle fracture by car accident were treated using the rehabilitation protocol in Korean Medicine. We estimated the outcome evaluating physical examination findings of the ankle joint, nu-meric rating scale, Olerud-Molander score, and walking state. After the treatment, we ob-served that ankle movement and muscular strength were improved. Moreover numeric rat-ing scale, Olerud-Molander score, and walking state of patients were improved. A re-habilitation in Korean Medicine can be effectively used for ankle fracture patients. The limi-tation of this study was the insufficient number of cases. Further studies are needed to de-sign a rehabilitation protocol in Korean Medicine. (J Korean Med Rehabil 2017;27(4): 171-184)