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2018, Vol.28, No.1

  • 1.

    Effects of Jeopgolsan (JGS) Extract on Fracture Healing

    Han-Gil Lee | Minseok Oh | 2018, 28(1) | pp.1~17 | number of Cited : 6
    Abstract
    Objectives The purpose of this study was to evaluate the effect of Jeopgolsan (JGS) extract on anti-oxidant, anti-inflammatory activities in RAW 264.7 cells and on factors related with fracture healing in skull fractured rat. Methods Experimental animals were divided into four groups: normal group without any treatment (Normal), contral group were treated orally with distilled water (Control), Experimental group were treated orally with JGS at a concentration of 200 mg/kg/day (JGS 200) and Experimental group were treated orally with JGS at a concentration of 200 mg/kg/day (JGS 400). Rats in each group except the normal group were induced fractures in the skull. <In vitro> The 1,1-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging activity and 2,2’-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid (ABTS) radical scavenging activity were measured to evaluate antioxidant activity. The production of nitric oxide (NO), interleukin- 1β (IL-1β), interleukin-6 (IL-6) and tumor necrosis factor-α (TNF-α) in the RAW 264.7 cells were measured to evaluate anti-inflammatory activity. <In vivo> The production of osteocalcin calcitonin, carboxy-terminal telepeptides of type II collagen (CTX II), transforming growth factor-β (TGF-β), bone morphogenetic protein-2 (BMP-2), Insulin and alkaline phosphatase (ALP) in serum of rats were measured to evaluate the effects of fracture healing at 0, 2, 4, and 6th week. X-rays were taken every 3 week from 0 to 6th week to evaluate fracture healing effect. Results 1. No cytotoxicity was observed. 2. DPPH and ABTS radical scavenging activity were increased in a concentration dependent manner, indicating anti-oxidant effect. 3. NO, IL-1β, IL-6, and TNF-α were not significantly changed, indicating no anti-inflammatory effect. 4. Osteocalcin, Calcitonin, TGF-β and ALP were significantly increased in the experimental groups. 5. CTX II, insulin were significantly decreased in the expermental groups. 6. Radiologic examination showed that union of fracture was promoted. Conclusions From above results, JGS showed significant results in factors related with fracture healing and radiologic examination. Threfore, JGS is expected to be effective in the treatment of fracture. (J Korean Med Rehabil 2018;28(1):1-17)
  • 2.

    Effects of Jinmu-tang on the Osteoarthritis by MIA in Rats

    Doo-Hwa Yang | Chang-Hoon Woo | Hee Duk An | 2018, 28(1) | pp.19~31 | number of Cited : 3
    Abstract
    Objectives The object of this study was to investigate the antioxidative and antiinflammatory effects of Jinmu-tang extract (JMT) on the Monosodium iodoacetate (MIA)-induced rat osteoarthritis. Methods To investigate the antioxidant capacities of JMT, we measured the total polyphenol and flavonoid, and 2,2-diphenyl-1-picrylhydrazyl (DPPH) and 2,2’-Azino-bis(3-ethyl- benzothiazoline-6-sulfonic acid) (ABTS) radical scavenging activity. To evaluate the antioxidative and antiinflammatory effects of JMT, the rats were divided into 5 groups (n=8). Normal group was not induced by MIA and treated at all (N), control group was induced by MIA and not treated at all (Con), positive control group was induced by MIA and orally administered indomethacin 5 mg/kg (Indo) and experimental groups were induced by MIA and orally administered JMT 100 mg/kg (JMT100) and JMT 200 mg/kg (JMT200) for 4 weeks. The changes of anti-type II collagen antibody in serum, heme oxygenase-1 (HO-1), phosphorylated inhibitor of κBα (p-IκBα), cyclooxygenase-2 (COX-2), inducible nitric oxide synthase (iNOS) and tumor necrosis factor alpha (TNF-α) in knee joint tissue and histopathological observation (Hematoxylin & Eosin and Safranin-O stain) were measured. Results Total polyphenol and flavonoid levels of JMT were 26.90±0.33 mg/g and 6.02±0.34 mg/g. IC50 of L-ascorbic acid and JMT of DPPH radical scavenging activity were 1.35±0.07 μg/ml and 52.95±0.97 μg/ml. IC50 of L-ascorbic acid and JMT of ABTS radical scavenging activity were 3.18±0.02 μg/ml and 91.49±1.74 μg/ml. In serum, the anti-type II collagen antibody levels of JMT100 and JMT200 groups were decreased significantly. In knee joint tissue, the HO-1 level of JMT200 was increased significantly. The p-IκBα and TNF-α levels of JMT200 were decreased significantly. The COX-2 and iNOS levels of JMT groups were decreased significantly. In histopathological observation, in comparison with Con, synovial tissue, cartilage and proteoglycan of JMT100 and JMT200 were well preserved. Conclusions According to the results, It is considered that JMT has antioxidant and antiinflammatory effects for MIA-induced rat osteoarthritis, so it could be applied to osteoarthritis treatment. (J Korean Med Rehabil 2018;28(1):19-31)
  • 3.

    A Review of the Pain and Function Assessment Instruments for Shoulder Disease Patients in Korean Medicine Clinical Studies Published in South Korea

    Geon-Yeong Lee | Hee-Geun Jo | SUL JAE UK and 1other persons | 2018, 28(1) | pp.33~51 | number of Cited : 3
    Abstract
    Objectives The purpose of this study is to analyze the current status of measurement instruments used to evaluate pain and function for shoulder disease patients in Korean Medicine clinical studies published in South Korea. Methods 5 Korean online databases from January 2007 to July 2017 were used to source articles for the review. Data of pain and function assessment instruments, measurement methods, time point and frequency for shoulder assessment were extracted. And it was analyzed by investigating the frequency of use for each item. Results A total of 78 studies met the selection criteria. There were many studies with no description for pain assessment instruments or inconsistent measurement methods. In the function assessment, the frequency of use was low and there were a lot of use of instruments with low validity and reliability. Conclusions To develop the objectivity of clinical research, further clinical studies, active use of measurement instruments, and standardization of measurement methods are needed. (J Korean Med Rehabil 2018;28(1):33-51)
  • 4.

    Reviewing Research of Eastern-Western Integrative Medicine Studies in Korea

    Kuk-In Han | Seon-Ho Shin | Gwang-Mook Lim and 2other persons | 2018, 28(1) | pp.53~60 | number of Cited : 7
    Abstract
    Objectives The purpose of this study is to analyze research trends on Eastern-Western integrative medicine in Korea. Methods We searched the studies on Eastern-Western integrative medicine in 5 Korean web database (NDSL, KoreanTK, KISS, OASIS, DBPIA). 66 research papers we founded. Results 13 papers were published at 2010. The studies on Eastern-Western integrative medicine were mainly published in the Journal of Society of Preventive Korean Medicine. 24 papers were case report, include 7 studies on neurology, 4 studies on each oncology and dermatology, 2 studies on each gastroenterology and ophthalmology and otorhinolaryngology, 1 study on each obstetrics and gynecology and endocrinology and nephrology. In 24 case reports, 7 kinds of Eastern medicine treatment method and 4 kinds of Western medicine treatment method were existed. In case reports, medication (100%), herbal medicine, acupuncture (95.8%), moxibustion (58.3%), cupping, infusion solution (25%), pharmacopuncture (20.8%), physical therapy (12.5%), laser, injection, rehabilitation (8.3%) were used. Conclusions In this study, we analyzed the trends of Eastern-Western integrative medicine in korea from 2010 to 2017. There were various studies about Eastern-Western integrative medicine. In case reports, Eastern-Western integrative medicine tend to concentrated on treatment not diagnosis. Not only treatment but also diagnosis is needed in Eastern-Western integrative medicine studies. (J Korean Med Rehabil 2018;28(1):53-60)
  • 5.

    Proposal of Checklists for Patient Safety in Miniscalpel Acupuncture Treatment of Cervical and Lumbar Spine: Pilot Trial

    Hee-Geun Jo | Min-Yeong Song | Sang-Hoon Yoon and 4other persons | 2018, 28(1) | pp.61~72 | number of Cited : 2
    Abstract
    Objectives The authors propose a new checklist model adapted for safety miniscalpel acupuncture procedure of cervical and lumbar spine. Methods On the basis of available literature and expert opinion, a prototype checklist was developed. The checklist was adapted on the basis of observation of daily practice. Results The checklist has three parts: 1. prevention and management of healthcare associated infections, 2. verification list before and after miniscalpel acupuncture treatment, 3. adverse event monitoring after procedure. We presented a summary checklist based on the above contents. Conclusions We propose the first patient safety checklist for minicalpel acupuncture treatment of cervical and lumbar spine. The checklist will be complemented using further research methodologies. (J Korean Med Rehabil 2018;28(1):61-72)
  • 6.

    A Web-based Survey for Assessment of Korean Medical Treatment Clinical Practice Patterns for Temporomandibular Disorders

    Chang-Eun Kim | Ho-Jeong Do | Hyun-Seop Song and 12other persons | 2018, 28(1) | pp.73~84 | number of Cited : 2
    Abstract
    Objectives While Temporomandibular disorders (TMD) is highly prevalent in Korea, studies examining its Korean medical treatment are currently lacking. The aim of this study was to assess current Korean medical treatment practice patterns for TMD. Methods A preliminary questionnaire was developed to investigate current practice patterns of TMD treatment and underwent further revision through external review. The final questionnaire was distributed as a web-based survey to 18,289 potential respondents by email. Results The response rate was 2.23%. Most participants replied that they received multiple Korean medicine interventions for TMD treatment consisting of such methods as acupuncture, chuna manipulation, electroacupuncture. The percentage of treatment services among uncovered services, which need to be covered by national health insurance was high in the order of pharmacopuncture, chuna manipulation, and herbal medicine. The most commonly used diagnostic examination tools for TMD was Physical examination and next was Imaging diagnosis. The frequency of TMD treatment was the highest at 2∼3 times per week (76%) and the period was from 4 to 12 weeks (63%). Conclusions This survey study helps determine current practice patterns of TMD, and recognizes the need for use of diagnostic devices in TMD treatment. These results are further anticipated to provide basic data for clinical practice guide lines (CPGs). (J Korean Med Rehabil 2018;28(1):73-84)
  • 7.

    Comparison Study about Surface Mapping of Motor Points in Biceps Brachii Muscle Using Surface EMG and Electric Probe

    Jaewon Park | Dongho Keum | 2018, 28(1) | pp.85~96 | number of Cited : 1
    Abstract
    Objectives This study was performed to compare the electrical methods of motor points mapping using surface EMG and electric probe (Pointer Excel II). Methods 32 healthy adults (male 16, female 16) were selected. and classified into two groups; surface EMG group, electric probe (Pointer Excel II) group. In surface EMG group, motor points were searched by recoding the compound muscle potentials. In electric probe (Pointer Excel II) group, motor points were searched by scanning the skin with Pointer Excel II at low level stimulation. The locations of the motor points were expressed as X and Y values in relation to the reference line. The horizontal reference line was set as elbow crease and the vertical reference line was set as the line connecting coracoid process to the center of the horizontal reference line. The data was analyzed by ‘Independent T-test’ and ‘equivalence test’. Results 1. The motor points of short head and long head of biceps brachii muscle were located at about 2/3 length of the vertical reference line from coracoid process and about 1/5∼1/4 length of the half of the horizontal reference line from the vertical reference line in both group. 2. The motor points of the short head were located more distally and close to the vertical reference line (p<0.001). 3. In surface EMG group, the motor points of the long head were located more laterally in the female than male. And the motor points of the long head were located more distally in the left side than right side (p<0.05). In electric probe (Pointer Excel II) group, similar tendency was observed but there was no statistically significant difference (p>0.05). 4. As a result of the equivalence test between surface EMG group and electric probe (Pointer Excel II) group, the confidence intervals of the difference were within the equivalence limit. Therefore, the locations of the motor points searched by two ways are equa l (p>0.05, equivalence interval=3%). Conclusions The results indicate that electric probe (Pointer Excel II) can be used to search the motor points instead of surface EMG. This might improve the clinical efficiency when using the motor points to treat muscle dysfunction. (J Korean Med Rehabil 2018;28(1):85-96)
  • 8.

    Proposal of East-West Integrative Medicine Manual for Rehabilitation after Knee Surgery

    Min-Yeong Song | Hee-Geun Jo | SUL JAE UK and 1other persons | 2018, 28(1) | pp.97~107 | number of Cited : 2
    Abstract
    Objectives This is one of the manuals of East-West integrative medicine which was created by the committee on integrative medicine of Chung-Yeon Korean Medicine Hospital. The purpose of this manual is to support clinical decision-making and communication between Korean and western medical staff in a Korean medicine hospital during the rehabilitation of patients after knee surgery. Methods The draft was made by two rehabilitation specialists in Korean medicine. After a rehabilitation specialist in western medicine reviewed the draft and exchanged their ideas, a revised version that reflects the goal of consultation was made. Then the committee agreed to adopt the manuals through the process of review and feedback in addition to face-to-face discussions. Results This manual describes clinical decision-making for rehabilitation after arthroscopic partial meniscus resection, meniscus refixation, reconstruction of anterior and posterior cruciate ligaments. Therefore, it contains the schedule of rehabilitation treatment by the surgical technique, general goal of the rehabilitation by phase, guide for patients and postoperative infection management. Conclusions Despite some limitations, this manual has significance as the first example of a decision-making protocol suggestion for East-West integrative rehabilitation treatment after a knee surgery in one medical institution. (J Korean Med Rehabil 2018;28(1):97-107)
  • 9.

    Proposal of East-West Integrative Medicine Manual for Rehabilitation after Shoulder Surgery

    Min-Yeong Song | Hee-Geun Jo | SUL JAE UK and 1other persons | 2018, 28(1) | pp.109~120 | number of Cited : 3
    Abstract
    Objectives This is one of the manuals of East-west integrative medicine which was created by the Committee on integrative medicine of Chung-Yeon Korean Medicine Hospital. The purpose of this manual is to support clinical decision making and communication during the rehabilitation of patients after shoulder surgery. Methods The drafting was done by two rehabilitation specialists in Korean medicine. After a rehabilitation specialist in western medicine reviewed the draft and exchanged their ideas, a revised version that reflects the goal of consultation was made. Then the Committee agreed to adopt the manuals through the process of review and feedback in addition to face-to-face discussions. Results This manual describes clinical decision making for rehabilitation after arthroscopic rotator cuff repair, SLAP repair, and arthrolysis. Therefore it contains the schedule of rehabilitation treatment through the surgical technique, general goal of the rehabilitation by phase, guide for patients and postoperative infection management. Conclusions The proposal of this manual has a significance for it provides information about decision making process and contents of treatment in one medical institution for East-west integrative rehabilitation treatment after shoulder surgery. (J Korean Med Rehabil 2018;28(1):109-120)
  • 10.

    Trends of Government Funded Research for Kampo Medicine in Japan and It’s Implication

    Chang-woon Jeung | Chang-Hyuk Choi | Hee-Geun Jo and 2other persons | 2018, 28(1) | pp.121~131 | number of Cited : 1
    Abstract
    Objectives We analyzed the trends of government-funded research on Kampo medicine in Japan to provide advanced evidence to R&D support policy for Korean medicine, and to introduce new research fields and trends to the researchers. Methods We reviewed the researches on Kampo medicine through ‘research-er.jp’ and ‘KAKEN’ database which contain R&D status in Japan and scientific research funding project issued by the Japan Ministry of Education, Culture, Sports, Science and Technology. Results Since 1976, government-funded research on Kampo medicine has been continuously announced, and now 533 tasks have been completed or are in progress. The average duration of the study is 2.54 years, but it has been prolonged to 3.52 years in recent years. 4∼5 million yen was supported per project for laboratory research, and an average of 44,342 thousand yen was supported per project for specialized laboratory research and clinical research. Conclusions Despite the absence of systematically supporting departments, the researches on Kampo medicine in Japan were qualitatively superior since they focused on providing the scientific basis for clinical application. As competition in the world's traditional medicine market becomes more intense, it is necessary to improve the competitiveness of Korean medicine. Therefore, a keen interest in Korean medicine and active support from the government is needed. (J Korean Med Rehabil 2018;28(1):121-131)
  • 11.

    Analysis of the Medical Market Share of Traditional East Asian Medicine (TEAM) in Taiwan Using National Health Insurance Research Database (NHIRD)

    Chang-woon Jeung | Chang-Hyuk Choi | Hee-Geun Jo and 1other persons | 2018, 28(1) | pp.133~144 | number of Cited : 2
    Abstract
    Objectives Since the health insurance coverage for traditional Korean medicine is very low, some physicians and researcher have suggested that government’s institutional support is needed for korean medicine field. Therefore We examine the use of traditional medicine and western medicine in Taiwan, which operates a similar health insurance system to Korea. Methods We selected several studies from Pubmed and NHIRD, that could be used to numerically evaluate the use of traditional medicine. We reviewed the current status of medical use in Taiwan and compare it with that of Korea. Results Through a total of 87 studies, We found that 26.59%∼31% of Taiwanese use Traditional medical institutions more than once a year, and the use of traditional medicine has been increasing since 2000. In adults than children, in women than men, the use rate of traditional medicine was high. Especially, herbal medicine was the most common intervention, accounting for 70% of traditional medical care. Conclusions The core of low insurance coverage for traditional Korean medicine is in lack of coverage for herbal medicine. Taiwan’s case shows that the unmet demand for traditional Korean medicine of the Korean population can exist widely. (J Korean Med Rehabil 2018;28(1):133-144)
  • 12.

    Post-stroke Spasticity Treated by Miniscalpel-Acupuncture: Three Case Report

    Sang-Hoon Yoon | Hee-Geun Jo | Min-Yeong Song | 2018, 28(1) | pp.145~152 | number of Cited : 2
    Abstract
    Post-stroke spasticity is a common complication that can be deleterious to the daily living function and quality of life of stroke survivor. This case report was conducted to introduce the use of miniscalpel-acupuncture as a novel method for the treatment of post-stroke spasticiy in three patients with chronic stroke. Patients received miniscalpel-acpuncuture treatment for 4∼7 session. The flexor digitorum brevis, pronator teres, pronator quadratus, brachioradialis, tibialis posterior, gastrocnemius on the affected side were needled. The main outcome were the Modified Ashworth Scale (MAS) muscle spasticity score and the range of motion. The evaluation indices were measured after the initiation of treatment and after treatment. After miniscalpel-acupuncture session, three patients improved as indicated in the MAS grade and range of motion. This retrospective case report presents miniscalpel-acupuncture as a potentially effective approach in Korean medicine rehabilitation treatment of post-stroke spasticity. Further research is needed to confirm these findings. (J Korean Med Rehabil 2018;28(1):145-152)
  • 13.

    A Case Report of Korean Medicine Treatment on Back Pain of a Parkinson’s Disease Patient

    Doo-Ri Kim | Joo-Won Kim | Won-Hyung Ryu and 4other persons | 2018, 28(1) | pp.153~160 | number of Cited : 3
    Abstract
    The purpose of the study is to explore the possibility of Korean medicine treatment on back pain of Parkinson’s disease patient through a case study. A Parkinson’s disease patient suffering from back pain and both limbs pain was hospitalized and treated with acupuncture and traditional medicine. We evaluated the treatment effect with Numerial Rate Scale (NRS), Oswestry low back pain disability questionnaire (ODI), EuroQol-Five Dimensions (EQ-5D), and Unified Parkinson’s Disease Rating Scale (UPDRS). As a result, back pain NRS, lower limbs pain NRS, ODI, EQ-5D, UPDRS turned out to be greatly improved from 9 to 3, 5 to 2, 80 to 64, −0.014 to 0.513, 122 to 37, respectively. This study suggested that Korean Medicine could be effective treatment for back pain of Parkinson’s Disease. Further clinical studies are needed to obtain definite conclusion. (J Korean Med Rehabil 2018;28(1):153-160)
  • 14.

    Peripheral Post-traumatic Cervical Dystonia Treated by Miniscalpel-Acupuncture: A Case Report

    Sang-Hoon Yoon | Hee-Geun Jo | Min Gu Kwon and 1other persons | 2018, 28(1) | pp.161~166 | number of Cited : 2
    Abstract
    This report describes the miniscalpel-acupuncture treatment of a 68-yr-old woman who had abnormal posture and involuntary dystonic movements of the head and neck. She suffered muscle contracture associated symptoms after she fell injured in 2014. Her neck had abnormal posture findings due to muscle tension. The spasms gradually worsened and did not respond to botulinum toxin injections. Involuntary dystonic movements may be due to peripheral post-traumatic cervical dystonia. Outcomes support cervical dystonia may be managed effectively with miniscalpel-acupuncture. Further research is recommended. (J Korean Med Rehabil 2018;28(1):161-166)
  • 15.

    Postoperative Rehabilitation of Korean Medicine for Ankle Fractures Treated by Open Reduction with Internal Fixation: 2 Case Reports with 5 Months Follow-Up

    Min Gu Kwon | Hee-Geun Jo | Hye-Rin Park and 1other persons | 2018, 28(1) | pp.167~173 | number of Cited : 3
    Abstract
    The purpose of this study is to report the effect of Korean medicine rehabilitation therapies in two patients with ankle fractures who underwent Open Reduction with Internal Fixation (ORIF). Two patients with fractures who received ORIF received acupuncture, electroacupuncture, herbal medicine, and physical therapy during hospitalization. Patients were evaluated for AOFAS score, NRS, ROM, and ankle circumference. Case 1 was improved from 30 points to 62 points on the AOFAS score, from 8 to 2 on the NRS, and from 33 cm to 30 cm on the ankle perimeter. ROM was improved in all directions. Case 2 showed an AOFAS score of 64 to 90 points, frome 5 to 2 on the NRS, and from 25 cm to 23.5 cm on the ankle perimeter. ROM was improved in all directions. The results of this study suggest that the treatment of Korean medicine has a meaningful effect on improvement and rehabilitation of ankle fracture patients who have received ORIF. (J Korean Med Rehabil 2018;28(1):167-173)
  • 16.

    Korean Medicine Therapy to Ruptured Anterior Cruciate Ligament with Meniscal Tears: Report of 4 Cases

    Gi-Eon Lee | Da-Young Byun | Si-Hoon Han and 2other persons | 2018, 28(1) | pp.175~184 | number of Cited : 2
    Abstract
    The purpose of this study is to report the effectiveness of complex Korean Medicine treatment for anterior cruciate ligament (ACL) injuries with meniscus tear. Four patients were treated with complex Korean Medicine by acupuncture, pharmacopuncture and herbal medication. We evaluated the improvement of knee pain and function by Numeric Rating Scale (NRS), Western Ontario and McMaster Universities Arthritis Index (WOMAC Index), EuroQol-5 Dimension Index (EQ-5D Index). After treatment, we found that knee pain was reduced and joint function was improved by NRS and WOMAC index in all cases. In the evaluation of health-related quality of life through EQ-5D index, there was no significant difference in patients with degenerative knee osteoarthritis and severe meniscal injury. This results show that complex Korean Medicine may be an effective option for ACL injuries with meniscus tear. Further clinical studies are needed to clarify the effect of Korean Medicine therapy on ACL injuries with meniscus tear. (J Korean Med Rehabil 2018;28(1):175-184)
  • 17.

    A Case Report of Superior Labrum from Anterior to Posterior Tear Patient Treated with Shinbaro Pharmacopuncture and Motion Style Acupuncture Treatment (MSAT)

    Ok Jun Kwon | Gil-Hwan Kim | Yeong-Guk Ju and 5other persons | 2018, 28(1) | pp.185~193 | number of Cited : 2
    Abstract
    The purpose of this study is to report the improved case of superior labrum from anterior to posterior tear patient treated with Shinbaro pharmacopuncture and motion style acupuncture treatment. We used Shinbaro pharmacopucture, motion style acupuncture treatment and other korean medicine treatment for this patient. This case is measured and assessed by visual analogue scale (VAS), shoulder range of motion (ROM) and shoulder physical examination (Neer test, O’Brien test). After treatment, VAS decreased and the patient showed improvement of range of motion. Also physical examination of shoulder was improved. Shinbaro pharmacopuncture and motion style acupuncture treatment are thought to be helpful to relieve pain and recover function on shoulder joints, although further study is needed. (J Korean Med Rehabil 2018;28(1):185-193)