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pISSN : 1976-9334 / eISSN : 2288-1522

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2010, Vol.10, No.1

  • 1.

    Randomized, Double Blind, Placebo-Controlled Study of Bofu-tsusho-san on Obese Patients

    이지은 , SONG YUN KYUNG , Lim Hyung Ho | 2010, 10(1) | pp.1~16 | number of Cited : 14
    Objectives The clinical trial was designed to investigate the safety and effects of Bofu-tsusho-san extracts on the change of the weight, body compositions, serum in obese patients. Methods This study was a 4-weeks, double blind, comparative clinical trial. Eligible subjects had a body mass index(BMI) greater than 25 kg/m² and waist circumference(WC) longer than 85 cm in woman or 90 cm in man. Among 38 subjects, 36 subjects were randomized either to Bofu-tsusho-san or placebo. After 4 weeks of treatment, we measured anthropometric factors(weight, height, WC, BMI etc.), abdominal fat area by CT scanning, serum lipid(total cholesterol(TC), triglyceride(TG), HDL cholesterol, LDL cholesterol), blood level of variety(glucose,adiponectine, leptin, C-reactive protein(CRP) etc.), blood pressure(BP). Adverse events also evaluated. Results BMI, BP, TG, CRP were reduced and weight, WC, score of KOQOL(Korean version of obesity-related QOL scale), SRI(Stress response inventory) were significant changed in Bofu-tsusho-san. But there were no considerable difference between Bofu-tsusho-san and placebo. there were no serious adverse events in either group. Conclusion There were limitations in this study that it conducted within a short period of 4 weeks. but its weight and WC loss effect was significant and it had few adverse events.
  • 2.

    Validation of Somatotype Drawing for Assessment of Childhood Obesity

    Lee Jong-Woo , Hyeheong Eom , 인창식 | 2010, 10(1) | pp.17~28 | number of Cited : 2
    Objectives It is significant to determine the validation of a self-administered somatotype drawing for the simple assessment of childhood obesity in elementary school and clinical practice. Methods The subjects were 202 children(112 boys and 90 girls) who answered a questionnaire for somatotype drawing and weremeasured for body components with bioelectrical impedance. The somatotype drawing of children was analysed according to the three criteria of childhood obesity - BMI percentile,obesity index and percent body fat, respectively. Results BMI, waist-hip ratio, skeletal musclemass and proteinmass had significant differences(p<.05) between boys and girls. Somatotype drawing had the highest correlation with BMI in both boys and girls, and also showed a high correlation with BMI percentile, obesity index and percent body fat. According to these criteria of childhood obesity, the somatotype drawing was the best consistent with the obesity index, next turn was the percent body fat and then the BMI percentile. Conclusions The validation of somatotype drawing for the assessment of childhood obesity was analysed according to BMI percentile, obesity index and percent body fat, and the somatotype drawing was the best consistent with obesity index in both boys and girls.
  • 3.

    Influence of Prescribed Gamitaeeumjowi-tang on Liver Function : Prospective Single-center Pilot Study

    Jin Yong Huei , Kang Sik Kim , In Yeop Han and 1 other persons | 2010, 10(1) | pp.29~40 | number of Cited : 5
    Objective The aim of this study was to evaluate the influence of Gamitaeeumjowi-tang(GTT) prescribed by doctors of korean(KMD) medicine on liver function. Methods For this single-center, prospective, observational study, we enrolled patients who wished to take GTT prescribed by KMD for losing weight. sixty(60) patients took GTT for 33.8 days and completed questionnaires. Liver function tests(LFTs) were performed bofore(first test) and after each GTT treatment(finish test). For LFT, T-bil, ALP, AST, ALT were measured. Result There were no significant changes in LFT data between the first and finish tests. At first test, levels of test seven(7) patients were more than twice of normal range of upper limit, levels of eight(8) patients were more than normal range of upper limit, less than twice of normal range of upper limit. At last test, levels of nine(9) patients were more than normal range of upper limit, less than twice of normal range of upper limit. Conclusion The current study showed that ingestion of GTT prescribed by KMD did not increase the frequency of abnormal LFTs, at least in the short term.
  • 4.

    Second to Fourth Digit Ratio and Sexually Dimorphic Body Composition

    박정현 , 송미영 , Hojun Kim and 1 other persons | 2010, 10(1) | pp.41~48 | number of Cited : 2
    Background The length of the second digit (the index finger) relative to the length of the fourth digit (the ring finger) is sexually dimorphic as males have a lower second to fourth digit ratio (2D:4D). There is evidence that sex differences in 2D:4D arise from in utero concentrations of sex steroids,with a low 2D:4D (male typical ratio) being positively related to prenatal testosterone, while a high 2D:4D (female typical ratio) is positively associated with prenatal oestrogen Objective To investigate possible associations between 2D:4D ratio and sexually dimorphic body composition Methods 2D:4D ratio, body mass index (BMI), waist circumference, waist-hip ratio (WHR), weight, and body fat percentage was measured from 46 men and 20 women Results Digit ratio was found to be significantly lower in men than in women. No significant correlation between 2D:4D ratio and body compositions was found for both men and women while digit ratio in obese men was significantly higher than normal weight men. Conclusion This finding dose not support the significant correlation between digit ratio and sexually dimorphic body composition. However digit ratio in obese men was significantly higher than normal weight men.
  • 5.

    A Clinical Case Study on the Changes of Body Composition and Blood Chemistry after Modified Fasting Therapy in a Patient with Obesity

    Koh-Woon Kim , Won Seok Chung , Chung, Seok Hee | 2010, 10(1) | pp.49~56 | number of Cited : 10
    This study was performed to report the effectiveness of modified fasting therapy using very-low-calorie-diet on a patient with obesity. The patient was diagnosed as severe obesity and participated in a 14-day fast with the Signature, a liquor which is made from fermented medical herbs and carbohydrates (intake <600 kcal/day) accompanying 7 prefasting relief days, and 16 days with stepwise reintroduction of food. The fasting patient also received intensive oriental medical treatments such as acupuncture, moxibustion, cupping therapy and was encouraged to take more than two hours' of walking exercise a day. We have evaluated the efficacy of treatments by measuring the changes of body composition and blood chemistry according to each period of fasting therapy. After treatment, Body Fat Mass of the patient was decreased more than Muscle Mass and the level of AST, ALT was decreased to normal range. These results suggest that the modified fasting therapy was effective on the patient with obesity. Key Words : Modified fasting therapy, Very-low
  • 6.

    The effect of oriental obesity therapy on Morbid obese patient with Type 2 Diabetes : Two Cases Report

    한효정 , Hyun-Jin Kim , 박은영 and 4 other persons | 2010, 10(1) | pp.57~63 | number of Cited : 5
    Objectives The purpose of this study is to investigate the clinical effect of oriental obesity therapy on morbid obese patient with Type 2 Diabetes. Methods Two cases of Type 2 Diabetes patient was treated with herbal medicine, electrolipolysis, dietetic therapy, and aerobic exercise during the treatment period. Results The diagnostic index (Weight, BMI, PBF, WHR, FPG, HgbA1C) was improved at the end of treatment. Conclusion The improvement of the patient with Type 2 Diabetes is identified through receiving oriental medical treatments, dietetic therapy, and aerobic exercises. Further research on medical treatments and long-term maintenance of weight loss for obese patients with Type 2 Diabetes should be needed in order to standardize the treatment methodology.