A manuscript is reviewed first for its format and suitability to the aims and scope of the journal. If a manuscript clears these criteria, it is sent to the two most relevant investigators in the field. The selection of the article will be based on the review outcome. If there is a discrepancy concerning the review, the selection will be decided pending further review by the Editorial Committee. The editor will inform the author about the final decision on acceptance/rejection for publication. All manuscripts are acknowledged on receipt and receive editorial review within 2 weeks. The first decision time on manuscripts sent for review is usually about 8 weeks. The revised manuscript must be re-submitted within 8 weeks. The authors will be received the final decision within 5-6 months after initial submission.