This study compares the distance education systems between University of Houston and Korea National Open University and analyzes how instructional technologies are applied in delivering their respective DE courses. The research results show that UH’s utilization of various instructional media is fairly balanced while KNOU is heavily dependent on broadcast media. In terms of cost-effectiveness by delivery mode, for UH, ITV is perceived as the most efficient form of instruction, while at KNOU, all broadcast media are deemed equally efficient. Lastly, quality assurance in DE programs must involve top instructional content as well as effective usage of delivery methods. It is suggested that KNOU utilize more interactive instructional technologies such as Internet platform while UH should improve the TV course quality.