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pISSN : 1598-0324

2020 KCI Impact Factor : 0.76
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2018, Vol.19, No.2

  • 1.

    A Short History of Bioethics in East Asian Countries; Experiences of China, Taiwan, Japan, and Korea

    KWON Ivo | 2018, 19(2) | pp.1~14 | number of Cited : 0
    Abstract
    Bioethics in East Asian countries(China, Taiwan, Japan, and Korea) began in late 1970s or early 1980s. It was influenced by the change of the society and healthcare system, the development of medical technology such as organ transplantation, and the uprising of advanced biotechnology. Though each country has different political and societal legislation, healthcare system and culture, technological field which is energetically sought for, and disputable ethical issues, they have some difficult problems and questions in common ; the conflict between the imported theories and the real field of healthcare and research, the split between the language of ethics and the real practice of ethics, and the coexist of the pre-modernity and the current modernity in its society. Bioethics should be a foundation of ethical practice in the real world. The experiences and current situation of these countries, who share the similar background, and a comparative study would some important implication to the right practice and the development of bioethics in Korea.
  • 2.

    A Study on Communicating experience process of organ transplant coordinator to brain-dead family

    Kim Geum Nam | Song, Yoonjin | 2018, 19(2) | pp.15~37 | number of Cited : 0
    Abstract
    Positive recognition and determination of organ donation by donor family members are crucial for the activation of organ donation in Korea. This study aims to analyze the communication attitude of the organ transplant coordinator and the counseling ability to determine the donation decision of the brain donor family. In particular, it is important to understand the psychological burden of organ transplant coordinators, who face with the family suffering from the loss of their family member, and to know how they can relieve this burden in the process of communication and experience of constructing trust with them. As a result, this study provides important basic data for better communicating with the brain-dead family, and also suggests the institutional improvement plans for activation of brain-death donation.
  • 3.

    Precision Medicine and Protection of Personal Information

    CHOI Kyungsuk | 2018, 19(2) | pp.39~56 | number of Cited : 2
    Abstract
    Precision medicine is a new paradigm of medical service based on various mass personal information often including human material. However, the development of big data brings about some worries on protection of personal private information as well as realization of precision medicine. Collecting personal private information follows the practice of obtaining informed consent. But some who use such information intend to collect it through the waiver of informed consent or without consent appealing to the concept that de-identified personal information is not personal private information. I raised a question of whether research on precision medicine can be carried out through the waiver of consent when we consider characteristics of information it pursues. I argue that the technology of big data makes us reconsider the concept that de-identified personal information is not personal private information. With the consideration of domestic acts, American regulations, and EU regulation, I argue that those current regulations on the waiver of informed consent and the concept of de-identification will be applied to particular cases with the consideration of the purpose of using personal information and the features of combined additional information, that de-identification is not enough to protect privacy in the era of big date because even anonymised personal information may become identifiable, and that we need the system to monitor the flow and management of information. In addition, we need to reconsider a research paradigm such as donation in obtaining personal information because information in itself is a material for commercialization in precision medicine.
  • 4.

    Privacy Issues in Large-Scale Genomics Research

    Cho, Eun Hee | 2018, 19(2) | pp.57~76 | number of Cited : 1
    Abstract
    The privacy of a participant in genomics research can be protected by preventing direct information leakage and making it impossible to trace the person using information in the public database. Genomic information is unique enough that one may identify an individual either directly using the information or by aggregating it with multiple sources of other information. Thus, preventing the identification of specific individuals with genomic data is of great concern in genomics research. This study investigated representative large-scaled genomics research projects to examine how the privacy-related risks of participating in large-scaled genomics research are communicated with participants. Specifically, this study reviews the informed consent forms and/or supplementary information sheets of the 1,000 Genomes Project, the UK Biobank, the USA Precision Medicine Cohort 'All of Us', and Korean Genome and Epidemiology Study. Information on the identifiability of genetic information was provided to the participants only in the 1,000 Genomes Project. The UK Biobank, USA Precision Medicine Cohort, and Korean Genome and Epidemiology Study focused on the risk of information leakage and described detailed measures to deal with this issue such as the de-identification and anonymization of direct identifiers. However, recent studies confirmed that de-identification methods does not provide sufficient protection for privacy in genomic research because genetic data could be re-identified when matched with reference genotype and/or linked to non-genetic databases. Therefore, future genomics research should provide more detailed information on the potential risks to their participants, including the potential re-identification of genomic information.
  • 5.

    Hype on the human embryo editing by CRISPR/Cas9 -based on the hype scoring of domestic and foreign newspaper articles

    Bang-Ook Jun | 2018, 19(2) | pp.77~84 | number of Cited : 2
    Abstract
    This study was conducted to evaluate the hype score of Korean and foreign newspaper articles on human embryo editing by CRISPR-Cas9. Through the T-test, it was found that articles of the domestic newspapers were more significantly hyped than those of the foreign newspapers (p <0.001). The reasons for the different reporting attitudes are estimated in terms of the press releases of the Ministry of Science and ICT, the researchers' paper on human embryo editing, and science reporting practice of media. Finally, the way to avoid hype through responsible human embryo editing was sought.