This study was to empirically analyze the mediating effect of burnout in the effect of job stress on job satisfaction of workers in the elderly welfare center after COVID-19. Through this, the purpose of this study was to improve the quality of social welfare services and to provide basic data that can increase job satisfaction of Elderly Welfare Center workers. The results of this study are as follows. First, job stress had a negative effect on job satisfaction. Second, burnout had a partial mediating effect on the effect of job stress on job satisfaction. Based on the results of this study, the following suggestions were made. First, the workload should be controlled to reduce the job stress of the workers in the elderly welfare center. Second, psychological and emotional support programs should be provided to reduce the burnout of the elderly welfare center workers.