This paper presents the structure and characteristics of local labor market in Daejeon and analyzes the mismatch and wage gap between men and women to suggest implications for job creation and regional employment policy. The unemployment rate in Daejeon was increased by 2.0% in 2013, 2.5% in 2014, 2.9% in 2016 and 3.3% in 2017, showing structural labor supply and demand discrepancies. In particular, in the case of the metal processing product industry, the average monthly wage for men is 4.39 million won and the average monthly wage for women is 2.83 million won, representing wage gap of 1.56 million won between men and women. According to the results of the gender wage gap analysis, marriage(MAR), education(EDU), employment contract(CONTRACT), age(), householder (HOUSEHOLD), and working period(TERM) were followed. The higher the value of marriage (MAR) in the human capital factor, the higher the value of wages compared to long-term skilled workers when re-employed after leaving the labor market temporarily due to marriage, childbirth, and childcare. This paper suggests that it is necessary to support continuous career training and development for women.