Propolis is a resinous material collected by bees from secretion of the plants, mixed with bee enzymes, wax and pollen and is known as a compound containing about 200 compounds and minerals. The most important substances are flavonoids, which are natural functional substances contained in various parts of the stems and flowers of plants and phenolic compounds which are pale yellow. It is reported to be the most important component of propolis that enhances immunity in vivo and shows physiologically functions such as antioxidant, antibacterial, anti-inflammatory, antiviral and anticancer. Propolis has a problem in commercialization due to its characteristic strong smell. The propolis without odor did not show cytotoxicity compared with the conventional propolis. The conventional was found to have a total phenol content of about 14%, the propolis without odor was about 10%, it was confirmed that there is no significant difference in the antioxidant effect. Tyrosinase inhibitory activity was insignificant in the existing propolis, at a concentration of 10 mg/ml of propolis that had been deodorized, tyrosinase inhibitory activity of about 7% was confirmed. Based on the above research results, the propolis material which has effectively removed the strong odor, is expected to be applied to the development of health functional food technology and functional cosmetics, and to be used for the development of various types of functional drinks.