This study provides a theoretical basis and implications for the optimal location selection of flagship stores, considering the various professional perspectives, which can be utilized as a useful index for market analysis in real estate industries. Moreover, this study examines the location determinants for the flagship stores based on AHP and Fuzzy methodologies. The determinants are categorized into 20 factors with 5 upper categories. To develop the importance weight of factors, AHP and Fuzzy methodologies are implemented based on the analysis of a survey conducted with experts, namely, global brand's store expansion managers and commercial real estate brokers, who have experiences in flagship store expansions. Research findings indicate the following five upper categories: environment, commerciality, location, consumer, and space. Meanwhile, based on the analysis, the following factors are arranged in the order of importance: market size, foot traffic, profitability, store location, fixed cost, and so on. Notably, store expansion managers deemed profitability, fixed costs, investment size, and marketing as the more important factors, whereas commercial real estate brokers consider the purchasing power, visibility, total size, and façade to be the essential factors. This study’s findings may help in the decision-making for the optimal location selection of flagship stores.