A Treatment Guideline for Neuropathic Pain

정국진; Lee, Jae Hyup; 황창주; 안면환

Study Design: A review of literature including definition, diagnosis and treatment of neuropathic pain. Objectives: To review and discuss the treatment guideline for neuropathic pain. Summary of Literature Review: Neuropathic pains are characterized by partial or complete somatosensory change caused by various disorders affecting central and peripheral nervous system, and are especially problematic because of their severity, chronicity and resistance to simple analgesics. Materials and Methods: Review of literature. Results: Tricyclic antidepressants and the anticonvulsants gabapentin and pregablin were recommended as first-line treatments for neuropathic pain. Opioid analgesics and tramadol were recommended as second-line treatments that can be considered for first-line use in selected clinical circumstances. Other medications such as dual reuptake inhibitors of both serotonin and norepinephrine would be used in severe cases. More invasive interventions (e.g., spinal cord stimulation) may sometimes be helpful. Conclusions: Treatment must be individualized for each patient and aggressive, combinatory pharmacotherapy and multidisciplinary approach are recommended for the treatment of neuropathic pain.

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REFERENCES (26)
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* 2022년 이후 발행 논문의 참고문헌은 현재 구축 중입니다.

[book] Merskey H / 1994 / Lumbar zygapophysial joint pain syndromes and definition of pain terms 2nded / IASP Press : 181~182

[journal] Hansson P / 2002 / Neuropathic pain: clinical characteristics and diagnostic workup / Eur J Pain (6 suppl) : 47~50

[journal] Max MB / 2002 / Clarifying the definition of neuropathic pain / Pain 96 : 406~407

[journal] Jensen TS / 2002 / Test the classification of pain: reply to Mitchell Max / Pain 96 : 407~408

[journal] Backonja MM / 2003 / Defining neuropathic pain / Anesth Analg 97 : 785~790

[journal] Dworkin RH / 2003 / Advances in neuropathic pain: diagnosis, mechanisms, and treatment recommendations / Arch Neurol 60 : 1524~1534

[journal] Cruccu G / 2004 / EFNS guidelines on neuropathic pain assessment / Eur J Neurol 11 : 153~162

[journal] Woolf CJ / 1999 / Neuropathic pain. Etiology, symptoms, mechanisms, and management / Lancet 353 : 1959~1964

[journal] Treede RD / 2008 / Neuropathic pain: redefinition and a grading system for clinical and research purposes / Neurology 29 : 1630~1635

[journal] Bennett M / 2005 / The S-LANSS score for identifying pain of predominantly neuropathic origin: Validation for use in clinical and postal research / J Pain 6 : 149~158

[journal] Gilron I / 2005 / Morphine, gabapentine, or their combination for neuropathic pain / N Engl J Med 352 : 1324~1334

[journal] Dworkin RH / 2007 / Parmacologic management of neuropathic pain: evidence-based recommendations / Pain 132 : 237~251

[journal] Gilron I / 2005 / Morphine, gabapentin, or their combination for neuropathic pain / N Engl J Med 352 : 1324~1334

[journal] Raja SN / 2002 / Opioids versus antidepressants in postherpetic neuralgia: a randomized, placebo-controlled trial / Neurology 59 : 1015~1021

[journal] Finnerup NB / 2005 / Algorithm for neuropathic pain treatment: an evidence based proposal / Pain 118 : 289~305

[journal] Bel S / 1991 / Dorsal column stimulation (DCS): cost to benefit analysis / Acta Neurchir Suppl(Wien) 52 : 121~123

[journal] Kumar K / 2006 / Spinal cord stimulation in treatment of chronic benign pain: challenges in treatment planning and present tatus, a 22-year experience / Neurosurgery 58 : 481~496

[journal] Kumar K / 2002 / Treatment of chronic pain with spinal cord stimulation versus alternative therapies;cost-effectiveness analysis / Neurosurgery 51 : 106~115

[journal] North RB / 2007 / Spinal cord stimulationversus reoperation for failed back surgery syndrome; a cost effectiveness and cost utility analysis based on a randomized, controlled trial / Neurosurgery 61 : 361~368

[journal] De Vries J / 2007 / Spinal cord stimulation for ischemic heart disease and peripheral vascular disease / Adv Tech Stand Neurosurg 32 : 63~89

[journal] Horsch S / 2004 / Spinal cord stimulation in the treatment of peripheral vascular disease; results of a single center study of 258 patients / Angiology 55 : 111~118

[journal] Harke H / 2005 / Spinal cord stimulation in sympathetically maintained complex regional pain syndrome type I with severe disability. A prospective clinical study / Eur J Pain 9 : 363~373

[journal] Taylor RS / 2006 / Spinal cord stimulation for complex regional pain syndrome: a systematic review of the clinical and cost-effectiveness literature and assessment of prognostic factors / Eur J Pain 10 : 91~101

[journal] Daousi C / 2005 / Electrical spinal cord stimulation in the long-term treatment of chronic painful diabetic neuropathy / Diabet Med 22 : 393~398

[journal] Fogel GR / 2003 / Management of chronic limb pain with spinal cord stimulation / Pain Pract 3 : 144~151

[journal] Ansari S / 2007 / Neurostimulation for refractory angina pectoris / Acta Neurochir Suppl 97 : 283~288

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