This study sought to propose desirable education direction for library-assisted instruction that uses human library in school library. For this purpose, this paper conducted a case study on the classes that use human library run by the library of S Girls’ High School in Seoul. The main study results are summarized below. First, S Girls’ High School Library implemented five human library programs in 2019, including improvement of perception on multi-culture, menstruation rights for all, generation-connecting MEMORO project, pregnancy and delivery, and improvement of perception on the disabled. Second, the students replied that they could imagine and immerse while listening to Human Book’s story and that it was good to be able to ask questions if they had any. They said that those who acted as Human Book gave realistic advice, which was meaningful giving them a lot to learn. Some students replied that their previously negative perception turned positive.