Purpose: This systematic literature review was conducted to organize and analyze the factors associated with health-related quality of life (HRQOL) for adults and vulnerable elderly in earthquake-hit areas. Methods: Based on the guidelines of Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) and National Evidence-based Healthcare Collaborating Agency (NECA), a literature search was conducted in nine electronic databases, gray literature, and other sources. Methodological quality was assessed using Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) by two researchers independently. Factors associated with HRQOL were extracted and categorized into sub-domains of the theory of HRQOL developed by Wilson and Cleary (1995). Results: Of the 432 studies screened, 30 meeting the criteria were analyzed-24 on adults and six on the elderly. Extracted factors associated with HRQOL were as follow; age, sex, living condition, injury, depression, and physical illness, etc. were associated with HRQOL for both adults and aged.
Social right, social activity decline, adaptation, and resilience were associated with HRQOL for adults, while activities of daily living were associated with HRQOL for the elderly. The extracted factors were categorized into individual characteristics, environmental characteristics, physiological factors, symptoms, and functional status.
Conclusion: In this review, factors associated with HRQOL for adults and the elderly in earthquake-hit areas were extracted and summarized. Community healthcare providers and community leaders could use these as evidence to formulate disaster management interventions and policies for vulnerable populations.