Just as globalization has many aspects and has developed in various, sometimes contradictory ways with both positive and negative impacts, so too would the reverse process of deglobalization have wide-ranging effects for individuals, communities, and nations. Some parts of globalization began to fray during the coronavirus pandemic (e.g. failing supply chains and disarray in the global shipping industry). Deglobalization would bring about much more significant changes in focusing on local production and consumption, eschewing non-essential flights and international tourism, and replacing personal experience with virtual presence. These impacts would be particularly severe for Vietnam, since its government has placed intensive connectivity with global production at the center of its model for the rapid development on which much of its legitimacy rests and it has joined as many international, multilateral organizations, and protocols as it has been able to do. Through critical analysis of secondary data from a wide range of sources, this paper examines the motivations that people, institutions, and governments might have to pursue deglobalization and then seeks evidence for whether the changes that would bring have started to affect Vietnam. While it is difficult to be too certain about this while the pandemic continues, it is evident that pressures are building in the global north to reconfigure supply chains for greater security, to reduce carbon emissions through regulating long-distance exchanges, and to withdraw from personal contacts. It is argued that a focus on digitalization in economy and society will help to mitigate the negative effects of deglobalization on Vietnam, at least in the medium-term.