2015, Vol.25, No.3

Journal of Korean Medicine Rehabilitation 2023 KCI Impact Factor : 0.6

pISSN : 1229-1854
https://journal.kci.go.kr/jkmr

ObjectivesTo evaluate Shinbaro Pharmacopuncture safety through analysis of potential single-dose intramuscular toxicity of Sinbaro Pharmacopucture in SD rats and Beagle dogs.MethodsSingle-dose intramuscular toxicity of Shinbaro Pharmacopuncture was as-sessed in accordance with Korea Food and Drug Administration Guidelines for toxicity test-ing of Medicinal Products. The SD rats were treated intramuscularly with Shinbaro Pharmacopuncture at doses of 0, 4.6, 9.2, and 18.5 mg/kg, respectively. The Beagle dogs were treated intramuscularly with Shinbaro Pharmacopuncture at doses of 2.3, and 4.6 mg/kg, respectively, and after 3 days, the procedure was repeated a second time at doses of 0.6, and 1.2 mg/kg, respectively, for toxicity testing. Mortality, change in body weight, and necropsy findings were examined for the study period.ResultsThere were no mortalities, general symptoms, or body weight changes in the SD rats. While pyelectasis of the left kidney was observed in a male rat in the 4.6 mg/kg admin-istration group, natural occurrence is common, and does not appear to be related with the test substance. No mortalities were observed in the Beagle dogs. In assessment of general symptoms, a female dog in the 9.2 mg/kg group displayed body weight decrease due to leftover food, but the change in body weight was within the normal range seen at 6~7 months, and the necropsy findings were not significant. The toxicity of the test substance appears to be minimal.ConclusionsThe results suggest that the lethal dose 50 (LD50) and approximate lethal-dose (ALD) value in single intramuscular administration of Shinbaro Pharmacopuncture in SD rats and Beagle dogs are higher than 18.5 mg/kg. (J Korean Med Rehab 2015;25(3):1-9)

ObjectivesThe purpose of this study is to assess the quality of spinal disease focusing on Korean medical hospital admission patients.MethodsThe disease code related to spinal disease was selected based on the con-tents of development of clinical quality indicators for spinal disease. The assessment analy-sis of feasibility was conducted through medical history analysis that targets spinal disease patients, current development of clinical quality indicators for spinal disease, and relevant literature.ResultsThe indicator items of structure, process, and results were classified and se-lected, and so were the detailed indicator entries. After that, the appropriate reference value was chosen. The final selected quality indicators were 3 items from structure, 9 items from process, 4 items from results, including 3 monitoring items, total 16 items was chosen.ConclusionsClinical research for the adequacy assessment should be conducted and the index entry and indicators should be reassessed through an expert group discussion. Training for the evaluation indicators and association with relevant society will motivate hos-pitals to voluntarily improve their quality. (J Korean Med Rehab 2015;25(3):11-26)

ObjectivesThe aim of this review is to analyze research trends on the Korean medical treatment and study of fracture.MethodsWe searched 38 studies related treatment of fracture via Korean medicine web databases. We classified these studies by three types (experimental reports, case reports and retrospective reports) and researched how to treat the patient of fracture.Results38 studies were published since 1993 and published every year since 2004 to 2013. There were 8 experimental reports, 20 case reports and 10 retrospective reports. Most of these studies were effective to treat of fracture. Bee venom treatment and Hua-Tuo-Jia-Ji-Xue acupuncture treatment were more effective than general treatment.ConclusionsThese results suggest that Korean medicine is effective treatment to frac-ture and we need continuously agonize and research more effective therapy method. (J Korean Med Rehab 2015;25(3):27-36)