The Influence of Predisposing Factors and Sign of Hypoadrenia on Autonomic Nervous System Activity and Salivary Cortisol (부신기능저하증의 예후인자와 증후가 자율신경 활성도와 타액 코티졸에 미치는 영향)

Jeong-Ho Lee (이정호); Myong Jong Yi (이명종); Seongmin Kim (김성민); Hojun Kim (김호준)

The Influence of Predisposing Factors and Sign of Hypoadrenia on Autonomic Nervous System Activity and Salivary Cortisol

Journal of Korean Medicine Rehabilitation
Abbr : JKMR
2008, 18(2), pp.131-142
Publisher : The Korean Academy Of Oriental Rehabilitation Medicine
Research Area : Medicine and Pharmacy > Korean Medicine

Jeong-Ho Lee ¹, Myong Jong Yi ², Seongmin Kim ¹, Hojun Kim ¹

¹동국대학교
²강원대학교

Accredited

ABSTRACT

Objectives : This study was performed to identify the influence of salivary cortisol and HRV(Heart rate variability) on hypoadrenia predisposing factors and sign. Methods : 30 patients with chronic fatigue symptom belonging to Shen xu(腎虛) were recruited for investigation from March to April 2007. The participants were divided into HS(High score) group(n=15) and LS(Low score) group(n=15) in predisposing factors of adrenal questionnaire. At the same time equal patients separated into OH(+)(Orthostatic hypotension positive) group(n=12) and OH(-)(Orthostatic hypotension negative) group(n=18). Salivary cortisol and HRV made use of evaluating hormonal imbalance and autonomic nervous system of hypoadrenia. Results : Salivary cortisol at P.M.4 in HS group was significantly(p=0.011) lower than LS group. And LF(Low frequency) of OH(+) group was considerably(p=0.014) lower than OH(-) group. Conclusions : Shen xu bian zheng(腎虛辨證), measure of orthostatic hypotension, predisposing factors of adrenal questionnaire, salivary cortisol and HRV deserve clinical application for management of subclinical hypoadrenia.

KEYWORDS

Hypoadrenia, Orthostatic hypotension, HRV, Salivary cortisol

Citation status

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