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Clinical Trial of Taeeumjowui -Tang(Taiyintiaowei-tang) on Obese Patients - Randomized, Double Blind, Placebo-Controlled Study -

  • Journal of Korean Medicine Rehabilitation
  • Abbr : JKMR
  • 2010, 20(4), pp.197-213
  • Publisher : The Korean Academy Of Oriental Rehabilitation Medicine
  • Research Area : Medicine and Pharmacy > Korean Medicine

이지은 1 SONG YUN KYUNG 1 Lim Hyung Ho 1

1경원대학교

Accredited

ABSTRACT

Objectives :The clinical trial was designed to investigate the safety and effects of Taeeumjowui-tang(Taiyintiaowei-tang) extracts on the change of the weight, body compositions, serum in obese patients. Methods :This study was a 12-weeks, randomized, double blind, placebo-controlled clinical trial. Patients with a body mass index of either greater than 30 kg/m2 or between 27 and 30 kg/m2 with controlled hypertension, diabetes, hyperlipidemia were considered eligible. Participants of 41 obese patients were randomized either to Taeeumjowui-tang(Taiyintiaowei-tang)(23) or placebo(18). After 12 weeks of treatment, we measured anthropometric factors(weight, height, waist circumference, BMI(body mass index) etc.), abdominal fat area by CT(computed tomography) scanning, serum lipid(total cholesterol, tryglyceride, HDL-cholesterol, LDL-cholesterol), blood level of variety(AST, ALT, BUN, creatinine etc.). Adverse events also evaluated. Results :After 12 weeks of treatment mean weight, waist-circumference, total cholesterol, LDL-cholesterol and score of KEAT-26 were significant changed in Taeeumjowui-tang (Taiyintiaowei-tang). There were no serious adverse events in either groups. Conclusions :There were limited in this study that it conducted within a short period of 12 weeks. but its weight and WC(waist circumference), WHR(waist hip ratio), total cholesterol, LDL-cholesterol and score of KEAT-26 loss effect was significant and it had few adverse events.

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