Association of GNB3 Polymorphism with Obesity Index, Blood Pressure, Glucose and Lipid Level (비만한 한국인에서 GNB3 유전자다형성과 비만 지표, 혈압, 혈당, 지질 대사의 관계)

권동현; 박정현; Myeong-Jong Lee (이명종); 송미영; Hojun Kim (김호준)

Association of GNB3 Polymorphism with Obesity Index, Blood Pressure, Glucose and Lipid Level

Journal of Korean Medicine Rehabilitation
Abbr : JKMR
2011, 21(4), pp.157-165
Publisher : The Korean Academy Of Oriental Rehabilitation Medicine
Research Area : Medicine and Pharmacy > Korean Medicine

권동현 ¹, 박정현 ¹, Myeong-Jong Lee ¹, 송미영 ¹, Hojun Kim ¹

¹동국대학교

Accredited

ABSTRACT

Objectives :The aim of this study is to establish the association of GNB3 with obesity-index, blood pressure, glucose and lipid level. Methods :A total of 209 Korean obese subjects participated in the study. Body weight, body mass index(BMI), waist circumference, body fat, body fat mass, resting metabolic rate, blood pressure, total cholesterol, high density lipoprotein, triglyceride and fasting blood sugar test were measured by using standardized protocols. The GNB3 was genotyped by using polymerase chain reaction with restriction fragment length polymorphism. Results :The frequency of CC, CT, TT genotype were, respectively, 18.2%, 56.9%, 24.9%, and the frequency of T allele was 53.3% in Korean obese population. There were no association of GNB3 with obesity index, blood pressure, glucose and lipid level in Korean obese population. Conclusions :Obese Korea population have a higher frequency of T alle than general Korean population. Threre are no association of GNB3 with obesity index, blood pressure, glucose and lipid level in Korean obese population.

KEYWORDS

GNB3 polymorphism, Obesity, Hypertension

Citation status

* References for papers published after 2023 are currently being built.

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