Journal of Korean Medicine Rehabilitation 2023 KCI Impact Factor : 0.6
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pISSN : 1229-1854
- https://journal.kci.go.kr/jkmr
KJCKorea
Journal Central
The Review on the Randomized Controlled Clinical Trials of Bee Venom in the Journal of Korean Medicine
- Journal of Korean Medicine Rehabilitation
- Abbr : JKMR
- 2013, 23(3), pp.87-106
- Publisher : The Korean Academy Of Oriental Rehabilitation Medicine
- Research Area : Medicine and Pharmacy > Korean Medicine
이용석 1, Young-Joon Lee 1, Han Chang Hyun 2
1대구한의대학교
2한국한의학연구원
Accredited
ABSTRACT
Objectives We will provide basic information on bee venom clinical tests and aid thepractical use of bee venom in such tests, through examination of RCT research related tobee venom that was reported domestically.
Methods We collected 365 articles on Bee venom study result from the OASIS systemusing the Keyword ‘bee venom, apitoxin, apitherapy, bee sting’. The initially selected theseswere primarily screened for clinical research. Out of these, case studies and nonrandomized controlled trial (non-RCT) were ruled out. As a result, 39 studies of randomizedcontrolled trial (RCT) research were chosen as the subjects of study.
Results RCT research related to bee venom was first presented in 2003, and 39 studieshave been published until 2012. 18 studies were tests to confirm the effectiveness of beevenom, 7 studies were comparisons between SBV and BV, and 13 studies were comparisonswith other types of treatment. Research conducted through appropriate randomizationmethods were 20 studies, and inappropriate randomization methods were used in19 studies. In therms of Jadad score, 12 studies received 4~5 points, 15 studies received1~3 points, and 12 studies received zero point.
Conclusions In order to assure good quality RCT research, appropriate guidelinesshould be provided, and proper evaluation standards should be established. In-depthstudy is needed concerning the difference of responses to treatment according to thetypes of treatment received. A standardization of treatment should be reached as a result.
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