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A Systematic Review and Meta-Analysis of Herbal Medicine for Frozen Shoulder

  • Journal of Korean Medicine Rehabilitation
  • Abbr : JKMR
  • 2019, 29(3), pp.15-33
  • DOI : 10.18325/jkmr.2019.29.3.15
  • Publisher : The Korean Academy Of Oriental Rehabilitation Medicine
  • Research Area : Medicine and Pharmacy > Korean Medicine
  • Received : June 13, 2019
  • Accepted : June 3, 2019
  • Published : July 31, 2019

Tae-Young Oh 1 Yeon-Hee Kim 2 Eun-Mi Oh 1 Su Min Hong 1 Hyun-Ju Ha 1 Eun-Jung Lee 1 Minseok Oh 1

1대전대학교 한의과대학 한방재활의학과교실
2대전대학교 한의과대학 한방재활의학과 교실

Accredited

ABSTRACT

Objectives The objective of this study is to provide the evidence of the effectivness of herbal medicine for frozen shoulder. Methods 2 Korean medical on-line databases (Oriental Medicine Advanced Searching Integrated System, Korean Traditional Knowledge), and 3 foreign databases (Pubmed, Cochrane library, China National Knowledge Infrastructure) were searched to find articles concerning herbal medicine for frozen shoulder. We selected randomized controlled trials (RCTs). Several repeated articles and those not relevant to the topic were excluded, as well as review articles and commentaries. The methodological quality of RCTs were evaluated using the Cochrane risk of bias tool and meta-analyes were perfomed. Results Total 474 studies were founded and 22 RCTs were selected for systematic review. Efficiency rate was used as the primary evaluation method. Almost studies reported that herbal medicine has significant effect on pain reduction, increasing shoulder function on frozen shoulder. 3 studies comparing herbal medicine and chuna with chuna and 3 studies comparing herbal medicine with ibuprofen were included in the meta-analysis. At herbal medicine and chuna with chuna meta-analysis, it showed positive results of herbal medicine for efficiency rate (risk ratio: 1.18, 95% confidence interval: 1.09-1.27, p<0.0001). At herbal medicine with ibuprofen medta-analysis, it showed positive results of herbal medicine for efficiency rate (risk ratio: 1.15, 95% confidence interval: 1.05-1.27, p=0.003). Conclusions The studies showed that herbal medicine can significantly effective on frozen shoulder. However, the risk of bias in RCTs were evaluated as uncertain. In the future, further well-designed RCTs are needed to prove the effectiveness of herbal medicine for frozen shoulder and reduce the risk of bias. (J Korean Med Rehabil 2019;29(3):15-33)

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