2026, Vol.16, No.

CELLMED 2025 KCI Impact Factor : 0.18

pISSN : 3022-6805 / eISSN : 3022-6791
https://journal.kci.go.kr/cellmed

Objective: Parkinson’s disease is a progressive neurodegenerative disorder characterized by the loss of dopaminergic neurons in the substantia nigra, with its incidence increasing markedly with age. The disease develops through the complex interplay of genetic, aging-related, environmental, and epigenetic factors, leading to the gradual onset of motor symptoms such as bradykinesia, rigidity, tremor, and gait disturbances. Current treatments are primarily limited to symptomatic relief, highlighting the need for novel therapeutic approaches capable of slowing disease progression. Case Report: The patient in this case report was a Korean man in his 70s who had been diagnosed with early-stage Parkinson’s disease and was taking prescribed medications. The patient experienced facial rigidity and generalized muscle loss, along with anxiety regarding the incurable nature of the disease and the limitations of available treatments in slowing its progression. Accordingly, Ortho-Cellular Nutrition Therapy (OCNT) incorporating Ginkgo biloba extract, vitamin C, and plant-based protein was administered. Following OCNT, improvements in facial rigidity and muscle loss were observed, along with overall improvements in physical condition, including sleep, bowel movements, and facial complexion. Conclusion: Although the findings of this single-patient case report cannot be generalized to all patients with Parkinson’s disease, they suggest the potential clinical utility of OCNT in improving symptoms. Whether OCNT can slow disease progression remains to be determined.

Objective: Colorectal cancer is a malignant tumor with high incidence and mortality rates worldwide, accounting for approximately 10% of all cancer-related deaths. Although various surgical treatments and chemotherapy regimens are currently available, the likelihood of recurrence and metastasis varies by disease stage. In particular, cases with serosal invasion or multiple lymph node metastases are classified as high-risk, and in such patients, it is important to establish appropriate treatment and management strategies considering factors such as lymphovascular invasion (LVI), perineural invasion (PNI), and carcinoembryonic antigen (CEA) levels. Recently, it has been suggested that Ortho-Cellular Nutrition Therapy (OCNT) may support recovery and symptom management after cancer treatment by improving overall cellular function. Case Report: A Korean man in his 50s was undergoing colectomy and adjuvant chemotherapy after being diagnosed with stage IIIC colorectal cancer. During treatment, he reported symptoms causing discomfort in daily life, including fatigue and weakness, anxiety, numbness in the hands and feet, loose stools, facial pallor, and weight loss. Accordingly, OCNT including anthocyanins, omega-3 fatty acids, selenium, zinc, vitamin D, resveratrol, butyrate-producing bacteria, and curcumin was prescribed. As a result, his symptoms gradually eased; during OCNT, CEA levels remained stable and decreased, and he was assessed as having no recurrence or metastasis. Conclusion: Although limited to a single patient, this case is considered to demonstrate the potential utility of OCNT as an adjunct to chemotherapy, based on notable improvement in bothersome symptoms, a stable clinical course, and the medical team’s assessment in a patient with high-risk colorectal cancer.

Objective: Chronic pruritus and musculoskeletal pain significantly impair patients’ quality of life. Both conditions may develop when pro-inflammatory cytokines elevated by low-grade systemic inflammation and aging lead to a persistent inflammatory state. In particular, when the cause of pruritus remains unidentified, treatment is often limited to symptomatic therapies, such as antihistamines and topical or systemic corticosteroids, which may carry a risk of adverse effects. In the present case, Ortho-Cellular Nutrition Therapy (OCNT) was administered to alleviate recurrent symptoms. Case Report: A Korean man in his 50s presented with pruritus of unknown etiology as his chief complaint, along with back muscle pain and left shoulder pain. A dermatology clinic diagnosed a skin disorder of unknown etiology and prescribed corticosteroids and antihistamines, and he also received treatment at a Korean medicine clinic. Although these treatments were effective during the first two months, his symptoms recurred in the third month. OCNT was therefore prescribed, and one month after its initiation, his pruritus improved and his muscle pain had almost completely resolved. Conclusion: Although this is a single case and the same OCNT regimen may not be applicable to all patients, the findings suggest that an appropriate OCNT regimen may contribute to alleviating oxidative stress and chronic inflammation by supporting the body’s antioxidant and anti-inflammatory functions. Furthermore, this case highlights the potential clinical value of OCNT in improving bothersome symptoms through an appropriate combination of nutrients, rather than relying solely on conventional symptomatic treatments for symptoms of unknown etiology.