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pISSN : 3022-6805 / eISSN : 3022-6791
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Medicinal plants used in the management of diabetes by traditional healers of Narok County, Kenya
- CELLMED
- Abbr : CellMed
- 2017, 7(2), pp.10-10
- Publisher : Cellmed Orthocellular Medicine and Pharmaceutical Association
- Research Area : Medicine and Pharmacy > General Medicine
Loice Njeri Kamau 1, Peter Mathiu Mbaabu 1, Peter Gathumbi Karuri 1, James Mucunu Mbaria 1, Stephen Gitahi Kiama 1
1University of Nairobi
Candidate
ABSTRACT
The Maasai community from Kenya is highly esteemed for their strong adherence to traditional cultures and ethno medicine. This is attributed to their age-old traditional mechanisms of passing down knowledge to the younger generation. Adoption to new socio-economic lifestyle and urbanization has been associated with development of diabetes, which has been reported among some indigenous pastoral communities in Kenya. Documentation of traditional methods of treatment and management of diabetes by the Maasai has not yet been reported, yet it is noteworthy. Thirty traditional healers from Narok County were purposively selected and interviewed about traditional knowledge of antidiabetic medicinal plants, parts used, preparation dosage and administration. A total of 14 antidiabetic plant species distributed within 13 genera and 12 families were identified and documented as herbal medicine used in the management of diabetes. The most highly cited plant species was Dovyalis abyssinica (20%), the plant family Flacourtiaceae and Rhamnaceae (2 plant species each) recorded the highest number of plant species while the most frequently used plant part was the roots (46%). Literature review revealed that some of the cited plants have known phytochemicals with antidiabetic activity; the study recommends further scientific investigation to validate their efficacy and safety.
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[journal]
Abdirahman YA
/ 2015
/ InVivo Anti-hyperglycemic Activity and Safety of The Aqueous Stem Bark Extracts of Aloe secundiflora
/ Med Aromat Plants
S1
: 003~
[journal]
Abebe D
/ 2005
/ Screening of some medicinal plants of Ethiopia for their anti-microbial properties and chemical profiles
/ J Ethnopharmacol
97
: 421~427
[journal]
Amabye TG
/ 2015
/ Evaluation of Phytochemical, Chemical Composition, Antioxidant and Antimicrobial Screening Parameters of Rhamnus prinoides (Gesho) Available in the Market of Mekelle, Tigray, Ethiopia
/ Nat Prod Chem Res
: 41~
[journal]
Amadi EK
/ 2013
/ Evaluation of herbal drugs used to treat fungal and bacterial diseases in Mbeere, Eastern Kenya
/ Int J Herbal Med
1
: 85~87
[journal]
Amuka O
/ 2014
/ Ethnobotanical Survey of Selected Medicinal Plants used by Ogiek Communities in Kenya against Microbial Infections
/ Ethnobot Res Appl
12
: 627~641
[journal]
Asad Mu
/ 2011
/ Acacia Nilotica Leave Extract and Glyburide : Comparison of Fasting Blood Glucose, Serum Insulin, β-Thromboglubulin Levels and Platelet Aggregation in Streptozotocin Induced Diabetic Rats
/ JPMA
61
: 247~
[journal]
Atieno JO
/ 2006
/ Diabetes management in a primary care setting : Kenyatta national hospital
/ Diabetes Voice
5
: 27~29
[journal]
Babby A
/ 2014
/ Current Antihyperlipidemic and Hepatoprotective activity of Tannic acid in Streptozotocin induced diabetic rats
/ Res Med Med Sci
4
: 9~12
[journal]
Banso A
/ 2009
/ Phytochemical and antibacterial investigation of bark extracts of Acacia nilotica
/ J med plants res
3
: 82~85
[web]
Berg PI
/ 2012
/ The Maasai keep healthy despite a high-fat diet
/ ScienceNordic: Research and Study
/ http://sciencenordic.com/maasai-keep-healthy-despite-high-fatdiet
[journal]
Berhanu MA
/ 1995
/ Emodin and emodinanthrone rhamnoside acetates from fruits of Rhamnus prinoides
/ Phytochemistry
39
: 1411~1414
[journal]
Bii C
/ 2010
/ The potential use of Prunus Africana for the control, treatment and management of common fungal and bacterial infections
/ J Med Plants Res
4
: 995~998
[journal]
Bussmann RW
/ 2006
/ Plant use of the Maasai of Sekenani Valley, Maasai Mara, Kenya
/ J Ethnobot Ethnomed
2
: 22~
[journal]
Campbell DJ
/ 2000
/ Land use conflict in Kajiado District, Kenya
/ Land Use Pol¬icy
17
: 337~438
[journal]
Campos KE
/ 2003
/ Hypoglycaemic and antioxidant effects of onion, Allium cepa : dietary onion addition, antioxidant activity and hypoglycaemic effects on diabetic rats
/ Int J Food Sci and Nutr
54
: 241~246
[journal]
Catalano S
/ 1984
/ New Constituents of Prunus africana Bark Extract
/ J Nat Prod
47
: 910~
[journal]
Chen YF
/ 2011
/ Relationship between antioxidant and antiglycationability of saponins, polyphenols, and polysaccharides in Chinese herbal medicines used to treat diabetes
/ J Med Plants Res
5
: 2322~2331
[journal]
Choi CW
/ 2015
/ Antiproliferation effects of selected Tanzania plants
/ Afr J Trad Complement Altern Med
12
: 96~102
[journal]
Christensen DL
/ 2009
/ Prevalence of glucose intolerance and associated risk factors in rural and urban populations of different ethnic groups in Kenya
/ Diabetes Res Clin Pract
84
: 303~310
[report]
Cochrane K
/ 2005
/ Family Fortunes: Analysis of Changing Livelihoods in Maasai land
/ Department for International Development
: 261~
[journal]
Day J
/ 1979
/ Biological variations associated with change in lifestyle among the pastoral and nomadic tribes of East Africa
/ Ann Hum Biol
6
: 1~
[book]
DeRuiter J
/ 2003
/ Endocrine Pharmacotherapy Module
/ Spring
[journal]
Desta B
/ 1995
/ Ethiopian traditional herbal drugs. Part I: Studies on the toxicity and therapeutic activity of local taenicidal medications
/ J Ethnopharmacol
45
: 27~33
[web]
/ Diet and Diabetes: Recipes for success
/ Physicians committee for responsible medicine
/ http://www.pcrm.org/health/health-topics/diet-and-diabetesrecipes-for-success
[book]
Engidawork E
/ 2011
/ Evaluation of anti-inflammatory and wound healing activities of the 80% methanol fruit extracts of Dovyalis abyssinica A. Rich. in mice
/ Addis Ababa University
[journal]
Fathy KE
/ 1996
/ Effect of Luffa aegyptiaca(seeds)and Carissa edulis(leaves)extracts on blood glucose level of normal and streptozotocin diabetic rats
/ J Ethnopharmacol
50
: 43~47
[journal]
Fourneau C
/ 1996
/ Triterpenes from Prunus africana bark
/ Phytochemistry
42
: 1387~1389
[journal]
Goto T
/ 2010
/ Various Terpenoids Derived from Herbal and Dietary Plants Function as PPAR Modulators and Regulate Carbohydrate and Lipid Metabolism
/ PPAR Res
2010
: 9~
[journal]
Granados S
/ 2015
/ Evaluation of the Hypoglycemic Effects of Flavonoids and Extracts from Jatropha gossypifolia L
/ Molecules
20
: 6181~6193
[journal]
Hemed E
/ 2014
/ How serious is the Impact of Type II Diabetes in Rural Kenya
/ The Open Diabetes J
7
: 1~4
[journal]
Hoffman B
/ 2007
/ Importance Indices in Ethnobotany
/ Ethnobot Res Appl
5
: 201~218
[book]
International Diabetes Federation
/ 2012
/ Expert Meeting on Indigenous Peoples, Diabetes and Development
/ world diabetes foundation
[journal]
Jeruto P
/ 2011
/ Phytochemical constituents of some medicinal plants used by the Nandis of South Nandi district, Kenya
/ J Anim Plant Sci
9
: 1201~1210
[web]
Karekezi C
/ 2011
/ Regional Differences in Prevalence of Diabetes among Medical Attendees in Kenya
/ Kenya Diabetes Management and Information Centre
/ http://www.ncdinfo-kenya.org/knowledgeportal/publications/1157/regional-differences-in-prevalence-ofdiabetes-among-medical-attendees-in-kenya
[journal]
Kareru PG
/ 2007
/ Traditional Medicines among the Embu and Mbeere Peoples of Kenya
/ Afr J Trad Complement Altern Med
4
: 75~86
[journal]
Kebenei JS
/ 2011
/ Anti-plasmodial activity of Nortrachelogenin from the root bark of Carissa edulis(vahl)
/ Int J Appl Res Nat Prod
4
: 1~5
[journal]
Keter LK
/ 2012
/ Ethnobotanical studies of medicinal plants used by Traditional Health Practitioners in the management of diabetes in Lower Eastern Province, Kenya
/ J Ethnopharmacol
139
: 74~80
[journal]
Kiringe JW
/ 2006
/ A Survey of Traditional Health Remedies Used by the Maasai of Southern Kaijiado District, Kenya
/ Ethnobot Res Appl
4
: 61~73
[journal]
Kiringe JW
/ 2005
/ Ecological and Anthropological Threats to EthnoMedicinal Plant Resources and their Utilization in Maasai Communal Ranches in the Amboseli Region of Kenya
/ Ethnobotany Research & Applications
3
: 231~241
[journal]
Kirira PG
/ 2006
/ Anti-plasmodial activity and toxicity of extracts of plants used in traditional malaria therapy in Meru and Kilifi Districts of Kenya
/ J Ethnopharmacol
106
: 403~407
[journal]
Koneri RB
/ 2014
/ Antidiabetic activity of triterpenoid saponin isolated from Momordica cymbalaria Fenzl
/ Ind J of Exp Biol
52
: 46~52
[journal]
Lans CA
/ 2006
/ Ethnomedicines used in Trinidad and Tobago for urinary problems and diabetes mellitus
/ J Ethnobiol Ethnomed
2
: 45~
[journal]
Lombard K
/ 2005
/ Quercetin in onion (Allium cepa L.) after heat-treatment simulating home preparation
/ J Food Composition Anal
18
: 571~581
[journal]
Lukačínová A
/ 2008
/ Structure-activity relationships of preventive effects of flavonoids in alloxan-induced diabetes mellitus in rats
/ J Anim and Feed Sci
17
: 411~421
[journal]
Mahmoud MF
/ 2013
/ Quercetin Protects against Diabetes-Induced Exaggerated Vasoconstriction in Rats: Effect on Low Grade Inflammation
/ PLoS One
8
: e63784~
[journal]
Maina JK
/ 2014
/ Hypoglycemic effects of selected herbal drug formulations from the Kenyan market
/ J Na Prod Plant Resour
4
: 10~17
[journal]
Maina W
/ 2011
/ Knowledge, attitude, and practices related to diabetes among community members in four provinces in Kenya : a cross-sectional study
/ Afr J Diabetes Med
19
: 15~18
[journal]
Mandha J
/ 2015
/ Risk Factors of Type 2 Diabetes among Maasai Pastoral Communities in Simanjiro, Tanzania
/ Open Access Library J
2
: e2079~
[journal]
Mangoyi R
/ 2011
/ In Vitro Antifungal Activities of Selected Medicinal Plants from Zimbabwe against Candida albicans and Candida krusei
/ Afr J Plant Sci Biotech
5
: 8~14
[journal]
Maobe MAG
/ 2013
/ Antimicrobial Activities of Eight Selected Medicinal Herbs Used for the Treatment of Diabetes, Malaria and Pneumonia in Kisii Region, Southwest Kenya
/ Global J Pharmacol
7
: 25~33
[journal]
Maobe MAG
/ 2012
/ Phytochemical Analysis of Phenol and Flavonoid in Eight Selected Medicinal Herbs Used for the Treatment of Diabetes, Malaria and Pneumonia in Kisii, Kenya
/ Acad J Cancer Res
5
: 31~39
[journal]
Masaki S
/ 2015
/ Type 2 Diabetes Prevalence and Risk Factors of Urban Maasai in Arusha Municipality and Rural Maasai in Ngorongoro Crater
/ J Appl Lif Sci Int
3
: 157~168
[journal]
Masevhe NA
/ 2015
/ The traditional use of plants to manage candidiasis and related infections in Venda, South Africa
/ J Ethnopharmacol
168
: 364~372
[journal]
Mbanya JC
/ 2010
/ Diabetes in sub-Saharan Africa
/ The Lancet
375
: 2254~2266
[journal]
Merawie Y
/ 2013
/ Antimicrobial activity of crude and semi-purified fractions of Warburgia ugandensis against some pathogens
/ J Coastal Life Med
1
: 233~240
[journal]
Mohan S
/ 2014
/ Role of various flavonoids : Hypotheses on novel approach to treat diabetes
/ J Med Hypotheses and Ideas
8
: 1~6
[book]
Mthethwa
/ 2009
/ Antimicrobial activity testing of traditionally used plants for treating wounds and sores at Ongoye area KwaZulu-Natal, South Africa
/ University of Zululand
[journal]
Mugisha MK
/ 2005
/ Traditional herbal remedies used in the management of sexual impotence and erectile dysfunction in western Uganda
/ Afr Health Sci
5
: 40~49
[journal]
Muregi FW
/ 2007
/ Antimalarial activity of methanolic extracts from plants used in Kenyan ethnomedicine and their interactions with chloroquine (CQ) against a CQ-tolerant rodent parasite, in mice
/ J Ethnopharmaco
111
: 190~195
[journal]
Muthee JK
/ 2011
/ Ethnobotanical study of anthelmintic and other medicinal plants traditionally used in Loitoktok district of Kenya
/ J Ethnopharmacol
135
: 15~21
[book]
Mwaniki M
/ 2007
/ Kenya : Experts sound alert over rising cases of diabetes among youth
/ The Nation
[journal]
Nahayo A
/ 2008
/ Chemical study of the stems of Urtica massaica, a medicinal plant eaten by the mountain Gorrillas (Gorilla beringei beringei) in Parc National des Volcans, Rwanda
/ Res J Appl Sci
3
: 514~520
[journal]
Nedi T
/ 2004
/ Diuretic effect of the crude extracts of Carissa edulis in rats
/ J Ethnopharmacol
95
: 57~61
[book]
Nicolai S
/ 2014
/ Beyond Basic : The growth of post-primary education in Kenya
/ Development progress
[journal]
Njoroge GN
/ 2009
/ Ethnotherapeutic management of sexually transmitted diseases(STDs)and reproductive health conditions in central province of Kenya
/ Indian J Trad Med
8
: 255~261
[journal]
Njoroge GN
/ 2006
/ Diversity and utilization of antimalarial ethnophytotherapeutic remedies among the Kikuyus(Central Kenya)
/ J Ethnobiol Ethnomed
2
: 8~
[journal]
Ochwang’i DO
/ 2014
/ Medicinal plants used in treatment and management of cancer in Kakamega County, Kenya
/ J Ethnopharmacol
151
: 1040~1055
[journal]
Odhiambo JA
/ 2009
/ Antifungal Activity Of Crude Extracts Of Selected Medicinal Plants Used In Combinations In Lake Victoria Basin, Kenya
/ Plant Prod Res J
13
: 35~43
[journal]
Oloro J
/ 2015
/ Toxicity of four herbs used in erectile dysfunction;Mondia whiteii, Cola acuminata, Urtica massaica, and Tarenna graveolens in male rats
/ Afr J Pharm Pharmacol
9
: 756~763
[journal]
Olowokudejo JD
/ 2008
/ An Ethnobotanical Survey of Herbal Markets and Medicinal Plants in Lagos State of Nigeria
/ Ethnobot Leaflets
12
: 851~865
[journal]
Omara EA
/ 2012
/ Therapeutic effect of Acacia nilotica pods extract on streptozotocin induced diabetic nephropathy in rat
/ Phytomedicine
19
: 1059~1067
[web]
Omollo CO
/ 2011
/ The Anti-malarial and Biochemical Studies of Microglossa pyrifolia (Lam.) Ktze and Trimeria grandifolia(Hochst.) Warb from LakeVictoria Basin
/ Kenya
/ http://ir.jkuat.ac.ke/bitstream/handle/123456789/883/Omollo%20C.%20O.%202011%20MSc%20Medicinal%20chemistry.pdf?sequence=1&isAllowed=y
[journal]
Onkamo P, S
/ 1999
/ Worldwide increase in incidence of Type I diabetes ± the analysis of the data on published incidence trends
/ Diabetologia
42
: 1395~1403
[journal]
Onyango CA
/ 2014
/ Phytochemical studies on herbal plants commonly used for processing and preserving meat and milk
/ J Appl Bioscie
73
: 5942~5948
[journal]
Orwa JA
/ 2007
/ TH and the management of Malaria in Kisumu District, Kenya
/ East Afri Med J
84
: 51~55
[journal]
Park JD
/ 2005
/ Biological activities and chemistry of saponins from Panax ginseng C. A. Meyer
/ Phytochem Rev
4
: 159~175
[journal]
Parker ME
/ 2007
/ Traditional dietary additives of the Maasai are antiviral against the measles virus
/ J Ethnopharmacol
114
: 146~152
[journal]
Patel SB
/ 2012
/ Antihyperglycemic and anti-hyperlipidemic effects of Bryonia laciniosa seed extract and its saponin fraction in streptozotocin-induced diabetes in rats
/ J Young Pharmacists
4
: 171~176
[web]
Patrick M
/ Ethnobotany of the Loita Maasai, Towards Community Management of the Forest of the Lost Child
/ http://unesdoc.unesco.org/images/0012/001266/126660e.pdf
[journal]
Phillips O
/ 1993
/ The useful plants of Tambopata Peru: I. Statistical hypotheses tests with a new quantitative technique
/ Econ Bot
47
: 15~32
[journal]
Pinent M
/ 2008
/ Bioactivity of Flavonoids on Insulin-Secreting Cells
/ Comprehensive Reviews Food Sci Food Safety
7
: 299~308
[journal]
Rafehi H
/ 2012
/ Mechanisms of action of phenolic compounds in olive
/ J Diet Suppl
9
: 96~109
[journal]
Rainer WB
/ 2013
/ Peril in the market-classification and dosage of species used as antidiabetics in Lima, Peru
/ J Ethnobiol Ethnomed
9
: 37~
[journal]
Rukunga GM
/ 2002
/ Evaluation of the HIV-1 reverse transcriptase inhibitory properties of extracts from some medicinal plants in Kenya
/ Afr J Health Sci
9
: 81~90
[book]
Sankan SS
/ 1995
/ The Maasai
/ Kenya Literature Bureau
[journal]
Sharma B
/ 2010
/ Antidiabetic potential of alkaloid rich fraction from Capparis decidua on diabetic mice
/ J Ethnopharmacol
127
: 457~462
[journal]
Sharma B
/ 2010
/ Antidiabetic potential of alkaloid rich fraction from Capparis decidua on diabetic mice
/ J Ethnopharmacol
127
: 457~462
[book]
Sindiga I
/ 1995
/ Traditional Medicine in Africa
/ East African Educational Publishers Ltd
[journal]
Singh BN
/ 2009
/ Polyphenolics from various extracts/fractions of red onion(Allium cepa)peel with potent antioxidant and antimutagenic activities
/ Food Chem Toxicol
47
: 1161~1167
[journal]
Tadesse B
/ 2015
/ In Vivo antitrypanosomal activity of dichloromethane and methanol crude leaf extracts of Dovyalis abyssinica(Salicaceae)against Trypanosoma congolense
/ BMC Complement Alt Med
15
: 278~
[journal]
Tiong SH
/ 2013
/ Antidiabetic and Antioxidant Properties of Alkaloids fromCatharanthus roseus (L.) G. Don
/ Molecules
18
: 9770~9784
[journal]
Tolo FM
/ 2006
/ Anti-viral activity of the extracts of a Kenyan medicinal plant Carissa edulis against herpes simplex virus
/ J Ethnopharmacol
104
: 92~99
[book]
Trowell HC
/ 1981
/ Western Diseases, Their Emergence and Prevention
/ Havard University Press
[journal]
Ugulu I
/ 2009
/ The investigation and quantitative ethnobotanical evaluation of medicinal plants used around Izmir province, Turkey
/ J Med Plants Res
3
: 345~367
[journal]
Uma MM
/ 2011
/ Phytomedicine for Diabetes mellitus : An overview
/ Res Pharmacy
1
: 28~37
[journal]
Verschaeve L
/ 2008
/ Mutagenic and antimutagenic properties of extracts from South African traditional medicinal plants
/ J Ethnopharmacol
119
: 575~587
[journal]
Wagate CG
/ 2010
/ Screening of some kenyan medicinal plants for antibacterial activity
/ Phytother Res
24
: 150~153
[journal]
Waihenya R
/ 2003
/ The phytochemical profile and identification of main phenolic compounds from the leaf exudate of Aloe secundiflora by high-performance liquid chromatography–mass spectroscopy
/ Phytochem Anal
14
: 83~86
[journal]
Wambugu SN
/ 2011
/ Medicinal plants used in the management of chronic joint pains in Machakos and Makueni counties, Kenya
/ J Ethnopharmacol
137
: 945~955
[book]
WHO
/ 2002
/ Traditional Medicine Strategy (2002-2005)
/ WHO
[journal]
Wild S
/ 2004
/ Global Prevalence of Diabetes Estimates for the year 2000 and projections for 2030
/ Diabetes Care
27
: 1047~1053
[book]
World Health organization
/ 2014
/ Non-communicable Diseases (NCD): Country Profiles
/ WHO
[journal]
Wube AA
/ 2005
/ Sesquiterpenes from Warburgia ugandensis and their antimycobacterial activity
/ Phytochemistry
66
: 2309~2315
[journal]
Yang W
/ 2010
/ Prevalence of Diabetes among Men and Women in China
/ N Engl J Med
362
: 12~
[journal]
Yin P
/ 2011
/ Hypoglycemic and Hypolipidemic Effects of Polyphenols from Burs of Castanea mollissima Blume
/ Molecules
16
: 9764~9774
[web]
Yonga G
/ 2011
/ Workshop on Country-Level Decision Making for Control of Chronic Diseases
/ The Institute of Medicine: The National Academies of Sciences, Engineering and medicine
/ http://iom.nationalacademies.org/Activities/Global/ControlChronicDiseases/2011-JUL-19/Day-2/Day-2-Part-1/Video17.aspx#sthash.BKorklnf.dpuf