@article{ART002649415},
author={Mohd. Tarique Ahsan and Seema Rani},
title={Evaluation of Anti-venom effect of Tiryaq-e-arba in rabbit models},
journal={CELLMED},
issn={3022-6805},
year={2020},
volume={10},
number={4},
pages={30-30},
doi={10.5667/CellMed.2020.0030}
TY - JOUR
AU - Mohd. Tarique Ahsan
AU - Seema Rani
TI - Evaluation of Anti-venom effect of Tiryaq-e-arba in rabbit models
JO - CELLMED
PY - 2020
VL - 10
IS - 4
PB - Cellmed Orthocellular Medicine and Pharmaceutical Association
SP - 30
EP - 30
SN - 3022-6805
AB - Background: Tiryaq-e-arba is a polyherbal Unani antidote/antivenom formulation used in the management of poisoning due to snake bite, scorpion bite as well as in cold poisons since time immemorial. Objectives: Tiryaq-e-arba was not evaluated scientifically before this study carried out, therefore it was studied for antivenom activity by testing on plasma fibrinogen level in Russell’s Viper envenomation in rabbits. Material &Methods: The anti-venom activity of the test drug was studied by observing its effect on plasma fibrinogen level in Russell’s Viper envenomation in rabbits by the method of Netelson. Results: The plasma fibrinogen level was found to be 171±665.04 mg/100 ml of blood, 36.18±1.12 mg/100 ml of blood, 33.14±0.52 mg/100 ml of blood and 17.9±1.65 mg/100 ml of blood at 0, 1, 3 and 6 hours respectively in control animals while in the test animal it was found to be 157.13±3.44 mg/100 ml of blood, 41.13±2.69 mg/100 ml of blood, 62.09±1.65 mg/100 ml of blood and 54.39±0.73 mg/100 ml of blood respectively. The test showed that though the plasma fibrinogen level in the test lower at 0 hour but it was greater in the control animals at 1, 3 and 6 hours. The increase in plasma fibrinogen level in the test animals at 3 and 6 hours was statistically significant (P<0.001). Conclusions: The finding of the present study was that Tiryaq-e-arba possesses antivenom activity which scientifically support the Unani claim that it is Dafe-Sumoom-al-Hevan (Antivenom or Antidote) and the use of this preparation in corresponding diseases.
KW - Anti venom activity;Antidote;Tiryaq-e-Arba;Unani medicine;Plasma fibrinogen level
DO - 10.5667/CellMed.2020.0030
ER -
Mohd. Tarique Ahsan and Seema Rani. (2020). Evaluation of Anti-venom effect of Tiryaq-e-arba in rabbit models. CELLMED, 10(4), 30-30.
Mohd. Tarique Ahsan and Seema Rani. 2020, "Evaluation of Anti-venom effect of Tiryaq-e-arba in rabbit models", CELLMED, vol.10, no.4 pp.30-30. Available from: doi:10.5667/CellMed.2020.0030
Mohd. Tarique Ahsan, Seema Rani "Evaluation of Anti-venom effect of Tiryaq-e-arba in rabbit models" CELLMED 10.4 pp.30-30 (2020) : 30.
Mohd. Tarique Ahsan, Seema Rani. Evaluation of Anti-venom effect of Tiryaq-e-arba in rabbit models. 2020; 10(4), 30-30. Available from: doi:10.5667/CellMed.2020.0030
Mohd. Tarique Ahsan and Seema Rani. "Evaluation of Anti-venom effect of Tiryaq-e-arba in rabbit models" CELLMED 10, no.4 (2020) : 30-30.doi: 10.5667/CellMed.2020.0030
Mohd. Tarique Ahsan; Seema Rani. Evaluation of Anti-venom effect of Tiryaq-e-arba in rabbit models. CELLMED, 10(4), 30-30. doi: 10.5667/CellMed.2020.0030
Mohd. Tarique Ahsan; Seema Rani. Evaluation of Anti-venom effect of Tiryaq-e-arba in rabbit models. CELLMED. 2020; 10(4) 30-30. doi: 10.5667/CellMed.2020.0030
Mohd. Tarique Ahsan, Seema Rani. Evaluation of Anti-venom effect of Tiryaq-e-arba in rabbit models. 2020; 10(4), 30-30. Available from: doi:10.5667/CellMed.2020.0030
Mohd. Tarique Ahsan and Seema Rani. "Evaluation of Anti-venom effect of Tiryaq-e-arba in rabbit models" CELLMED 10, no.4 (2020) : 30-30.doi: 10.5667/CellMed.2020.0030