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Effect of herbal medicine in male factor infertility (Oligoasthenoteratozoospermia) – A case report

  • CELLMED
  • Abbr : CellMed
  • 2025, 15(2), pp.15~21
  • DOI : 10.5667/CellMed.2025.003
  • Publisher : Cellmed Orthocellular Medicine and Pharmaceutical Association
  • Research Area : Medicine and Pharmacy > General Medicine
  • Received : February 5, 2025
  • Accepted : February 25, 2025
  • Published : February 28, 2025

Zainab Zubair 1 Mohamed Noorul Ameen 1

1National Ayurveda Teaching Hospital

Accredited

ABSTRACT

Introduction: Infertility is defined as the failure to conceive after one or more years of regular, unprotected coitus. According to the World Health Organization, male factor infertility accounts for 40 to 50 percent among the 60 to 80 million infertile couples worldwide. Semen analysis is a vital tool in the assessment of male infertility. Oligoasthenoteratozoospermia, a condition in which a semen sample comprises oligospermia/oligozoospermia, asthenozoospermia, and teratozoospermia, is common among men from infertile couples. Case Presentation: A 32-year-old married man sought treatment for six years of infertility. His seminal fluid analysis revealed oligoasthenoteratozoospermia. Internally, Mucuna purulence seed powder and Withania somnifera root powder, 5 g each, were prescribed twice daily after meals with milk, while Nigella sativa seed powder was administered 2.5 g twice daily after meals. Following three months of treatment, his seminal fluid analysis revealed a consistent improvement in the sperm parameters. Sperm volume increased from 1.3 ml to 1.7 ml, sperm concentration rose from 1.3 million/ml to 3 million/ml, overall sperm motility increased from 15% to 24%, progressive motility from 00% to 04%, and non-progressive motility from 15 to 20%, while non-motile sperm decreased from 85% to 76%. Conclusion: The seminal fluid analysis findings reveal that herbal medicine can be beneficial in managing male factor infertility by avoiding primary methods of treatment that are expensive and have a variety of undesirable side effects despite their inadequate efficacy rates, as well as secondary measures.

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