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Review of recently reported Ricin detection techniques focusing on combined immunoassay detection with abrin and saxitoxin in human plasma

  • Journal of Advances in Military Studies
  • Abbr : AdvMil
  • 2023, 6(2), pp.197~212
  • DOI : 10.37944/jams.v6i2.191
  • Publisher : Institute of Defense Acquisition Program
  • Research Area : Social Science > Military Science > Other Military Science
  • Received : February 10, 2023
  • Accepted : August 25, 2023
  • Published : August 31, 2023

Kang, Seungmin 1 Kim, Seonhee 2 Churchill, David G. 3 Kang, Ku 1 Jang, Yoonjeong 4

1국군화생방방어연구
27사단 화생방대대
3KAIST 화학과
4국군화생방방어연구소

Accredited

ABSTRACT

Increasing non-traditional threats from biological or chemical weapons, the Organisation for the Prohibition of Chemical Weapons (OPCW) have tried to perform the preliminary analysis of biotoxin sample to standardize analysis methods and strengthen analytical capabilities among OPCW member countries. With the changes of new analysis, ROK CBRN Defense Research Institute (CDRI) established enzyme-linked immunosorbent assay (ELISA) and cytotoxicity analysis methods for ricin, abrin, and saxitoxin through the OPCW exercise on Biotoxin sample analysis. Thus, this study aims to established analytical methods (ELISA and cytotoxicity analysis) for the biological toxins called ricin, abrin and saxitoxin according to recent OPCW Biotoxin detection exercise. In particular, to refine practical and effective methods of biological analysis, we reviewed recent research on scientific analysis of ricin as a potential bioterror weapon, letter with ricin sent in White House, and suggested future agendas for preparedness testing.

Citation status

* References for papers published after 2025 are currently being built.