@article{ART001822467},
author={박종철 and Howon Park and Lee, Si Young},
title={Enhancement of Erythrosine Photodynamic Therapy against Streptococcus mutans by Chlorhexidine},
journal={Journal of the Korean academy of pediatric dentistry},
issn={1226-8496},
year={2013},
volume={40},
number={4},
pages={241-246},
doi={10.5933/JKAPD.2013.40.4.241}
TY - JOUR
AU - 박종철
AU - Howon Park
AU - Lee, Si Young
TI - Enhancement of Erythrosine Photodynamic Therapy against Streptococcus mutans by Chlorhexidine
JO - Journal of the Korean academy of pediatric dentistry
PY - 2013
VL - 40
IS - 4
PB - The Korean Academy Of Pediatric Dentistry
SP - 241
EP - 246
SN - 1226-8496
AB - The purpose of this study was to investigate the synergistic effects of erythrosine sensitized with a conventional halogen curing unit and sub-minimal bactericidal concentration(sub-MBC) of chorhexidine on bacterial viability of Streptococcus mutans in planktonic state.
Sub-minimal bactericidal concentration of chlorhexidine was added into wells containing bacteria and erythrosine.
The range of concentrations tested for chorhexidine was from 0.0000001% to 0.001%. The irradiation of the bacterial suspensions was performed for 15 sec with a conventional halogen curing unit light. In another set of experiment, the effects of 0.001% chlorhexidine were observed by adding chlorhexidine into wells containing the sub-minimal bactericidal concentration of erythrosine.
At the concetration of 0.001% chlorhexidine, there were no antibacterial effects in the absence of erythrosine PDT(p < 0.05). At the concentraton of 1 μM erythrosine, there was no photodynamic therapy effect in the absence of chlorhexidine(p < 0.05). But in the presence of sub-minimal bactericidal concentration of erythrosine with light exposure, the addition of 0.001% chlorhexidine increased the bactericidal rate(p < 0.05).
A combination of erythrosine PDT with sub-MBC chlorhexidine resulted in a significant reduction in bacterial counts when compared to the case with the absence of chlorhexidine.
KW - Photodynamic therapy;Erythrosine;Halogen;Streptococcus mutans;Chlorhexidine
DO - 10.5933/JKAPD.2013.40.4.241
ER -
박종철, Howon Park and Lee, Si Young. (2013). Enhancement of Erythrosine Photodynamic Therapy against Streptococcus mutans by Chlorhexidine. Journal of the Korean academy of pediatric dentistry, 40(4), 241-246.
박종철, Howon Park and Lee, Si Young. 2013, "Enhancement of Erythrosine Photodynamic Therapy against Streptococcus mutans by Chlorhexidine", Journal of the Korean academy of pediatric dentistry, vol.40, no.4 pp.241-246. Available from: doi:10.5933/JKAPD.2013.40.4.241
박종철, Howon Park, Lee, Si Young "Enhancement of Erythrosine Photodynamic Therapy against Streptococcus mutans by Chlorhexidine" Journal of the Korean academy of pediatric dentistry 40.4 pp.241-246 (2013) : 241.
박종철, Howon Park, Lee, Si Young. Enhancement of Erythrosine Photodynamic Therapy against Streptococcus mutans by Chlorhexidine. 2013; 40(4), 241-246. Available from: doi:10.5933/JKAPD.2013.40.4.241
박종철, Howon Park and Lee, Si Young. "Enhancement of Erythrosine Photodynamic Therapy against Streptococcus mutans by Chlorhexidine" Journal of the Korean academy of pediatric dentistry 40, no.4 (2013) : 241-246.doi: 10.5933/JKAPD.2013.40.4.241
박종철; Howon Park; Lee, Si Young. Enhancement of Erythrosine Photodynamic Therapy against Streptococcus mutans by Chlorhexidine. Journal of the Korean academy of pediatric dentistry, 40(4), 241-246. doi: 10.5933/JKAPD.2013.40.4.241
박종철; Howon Park; Lee, Si Young. Enhancement of Erythrosine Photodynamic Therapy against Streptococcus mutans by Chlorhexidine. Journal of the Korean academy of pediatric dentistry. 2013; 40(4) 241-246. doi: 10.5933/JKAPD.2013.40.4.241
박종철, Howon Park, Lee, Si Young. Enhancement of Erythrosine Photodynamic Therapy against Streptococcus mutans by Chlorhexidine. 2013; 40(4), 241-246. Available from: doi:10.5933/JKAPD.2013.40.4.241
박종철, Howon Park and Lee, Si Young. "Enhancement of Erythrosine Photodynamic Therapy against Streptococcus mutans by Chlorhexidine" Journal of the Korean academy of pediatric dentistry 40, no.4 (2013) : 241-246.doi: 10.5933/JKAPD.2013.40.4.241
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