Validity of the New Caries Activity Test using Real-Time Polymerase Chain Reaction (실시간 중합효소연쇄반응 방법을 이용한 새로운 치아우식 활성 검사법의 유효성)

Doyoun Kwon (권도윤); Heejin Kim (김희진); NAM OK HYUNG (남옥형); Kim Mi Sun (김미선); Chul Choi Sung (최성철); KIM， KWANG CHUL (김광철); Lee Hyo-Seol (이효설)

doi:10.5933/JKAPD.2018.45.3.354

Validity of the New Caries Activity Test using Real-Time Polymerase Chain Reaction

Journal of the Korean academy of pediatric dentistry
Abbr : J Korean Acad Pediatr Dent
2018, 45(3), pp.354-362
DOI : 10.5933/JKAPD.2018.45.3.354
Publisher : The Korean Academy Of Pediatric Dentistry
Research Area : Medicine and Pharmacy > Dentistry
Received : September 19, 2017
Accepted : December 27, 2017
Published : August 31, 2018

Doyoun Kwon ¹, Heejin Kim ², NAM OK HYUNG ¹, Kim Mi Sun ³, Chul Choi Sung ⁴, KIM， KWANG CHUL ⁴, Lee Hyo-Seol ⁴

¹경희의료원
²경희대학교 치의학전문대학원 소아치과학교실
³강동경희대학교병원
⁴경희대학교

Accredited

ABSTRACT

Periogen is a new caries activity test using real-time polymerase chain reaction. The aim of this study was to assess the validity of Periogen by evaluating the correlation with dmft, dmfts indices and comparing with Cariview and caries risk assessment tool (CAT). 83 children under 6 participated in this study. Dmft, dmfts indices and CAT were collected through an examination of oral health status. Plaque samples for Periogen and Cariview were collected and manipulated according to the manufactures’ instructions. The correlation coefficient of Periogen, Cariview and CAT with the dmfts index were 0.38, 0.56 and 0.66 in each (p < 0.01). The sensitivity of Periogen, Cariview and CAT were 43%, 76% and 95% and specificity were 80%, 72% and 74% respectively. Area under curve under the receiver operating characteristic curves in each method indicated 0.69, 0.81 and 0.85. CAT and Cariview were more effective in evaluation the risk of dental caries than Periogen so far. To be used Periogen clinically, more improvements for higher validity were needed.

KEYWORDS

Caries activity test, Validity, Periogen, Cariview, Caries risk Assessment Tool, Real-time polymerase chain reaction

Citation status

* References for papers published after 2023 are currently being built.

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This paper was written with support from the National Research Foundation of Korea.

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Journal of the Korean academy of pediatric dentistry 2023 KCI Impact Factor : 0.48

Validity of the New Caries Activity Test using Real-Time Polymerase Chain Reaction

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Citation status

* References for papers published after 2023 are currently being built.

Journal of the Korean academy of pediatric dentistry 2023 KCI Impact Factor : 0.48

Validity of the New Caries Activity Test using Real-Time Polymerase Chain Reaction

ABSTRACT

KEYWORDS

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