본문 바로가기
  • Home

Application of Teeth Whitening LED for Prevention of Dental Caries : Antimicrobial Photodynamic Therapy Approach

  • Journal of the Korean academy of pediatric dentistry
  • Abbr : J Korean Acad Pediatr Dent
  • 2020, 47(1), pp.70-77
  • DOI : 10.5933/JKAPD.2020.47.1.70
  • Publisher : The Korean Academy Of Pediatric Dentistry
  • Research Area : Medicine and Pharmacy > Dentistry
  • Received : September 8, 2019
  • Accepted : November 4, 2019
  • Published : February 29, 2020

Choa Park 1 Howon Park ORD ID 2 LEE JU HYUN ORD ID 2 Hyunwoo Seo ORD ID 2 Lee, Si Young ORD ID 2

1강릉원주대학교 치과대학 소아치과학교실 및 구강과학연구소
2강릉원주대학교

Accredited

ABSTRACT

The present study is aimed to assess the effect of antimicrobial photodynamic therapy (aPDT) on Streptococcus mutans biofilm through teeth whitening light emitting diode (LED). Planktonic and dynamic biofilm state cultures of S. mutans were used. Erythrosine 20 μM/L was used as the photosensitizer. Irradiation was performed by exposing cultures to clinic and homecare whitening LEDs for 15 minutes. The viability was measured through Colony Forming Unit counts and confocal laser scanning microscopy. aPDT using whitening LEDs and erythrosine significantly decreased the CFU count of S. mutans compared to that in the control group. Dynamic biofilm group showed more resistant features to aPDT compared with planktonic state. Clinic and homecare whitening LED device showed similar antimicrobial effect. The whitening LED, which could irradiate the entire oral arch, showed a significant photodynamic effect on cariogenic S. mutans biofilm. aPDT mediated by erythrosine and LEDs used for teeth whitening exhibited promising antimicrobial activity.

Citation status

* References for papers published after 2022 are currently being built.