The Effect of Silver Diamine Fluoride on Salivary Biofilm (Silver diamine fluoride가 타액 생물막에 미치는 영향)

Meekyung Seo (서미경); Ji-Soo Song (송지수); Shin Teo Jeon (신터전); Hong-Keun Hyun (현홍근); Kim, JungWook (김정욱); Jang, KiTaeg (장기택); Sang-Hoon Lee (이상훈); Kim, Young J (김영재)

doi:10.5933/JKAPD.2020.47.4.406

The Effect of Silver Diamine Fluoride on Salivary Biofilm

Journal of the Korean academy of pediatric dentistry
Abbr : J Korean Acad Pediatr Dent
2020, 47(4), pp.406-415
DOI : 10.5933/JKAPD.2020.47.4.406
Publisher : The Korean Academy Of Pediatric Dentistry
Research Area : Medicine and Pharmacy > Dentistry
Received : June 9, 2020
Accepted : July 7, 2020
Published : November 30, 2020

Meekyung Seo ¹, Ji-Soo Song ², Shin Teo Jeon ², Hong-Keun Hyun ², Kim, JungWook ², Jang, KiTaeg ², Sang-Hoon Lee ², Kim, Young J ²

¹서울대학교 치의학대학원 소아치과학교실
²서울대학교

Accredited

ABSTRACT

Silver diamine fluoride (SDF) is an effective and efficient agent for arresting dental caries. It can be useful in treating children with behavioral or medical limitations. The purpose of this study was to evaluate the antimicrobial effect of SDF by using salivary biofilm. Pellicle-like saliva coated structure was prepared by using unstimulated saliva. For developing cariogenic biofilm, Streptococcus mutans was added to the mixture of pooled saliva and inoculated into a saliva coated glass or chamber. SDF was applied to cariogenic biofilm to evaluate the antimicrobial effect of SDF. As time passed, total bacteria and S. mutans were reduced after application of SDF (p < 0.000). Confocal laser scanning microscope also showed the increment of the ratio of dead cell. As a result of experiment using enamel and dentin of primary teeth, it was confirmed that the growth of cariogenic biofilm was inhibited when the SDF was treated (p = 0.029 each). This study showed excellent anti-microbial effect of SDF. And anti-caries effect in clinical practice can be expected.

KEYWORDS

Silver diamine fluoride, Silver compounds, Salivary biofilm, Cariogenic biofilm, Primary teeth

Citation status

* References for papers published after 2023 are currently being built.

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Journal of the Korean academy of pediatric dentistry 2023 KCI Impact Factor : 0.48

The Effect of Silver Diamine Fluoride on Salivary Biofilm

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* References for papers published after 2023 are currently being built.

Journal of the Korean academy of pediatric dentistry 2023 KCI Impact Factor : 0.48

The Effect of Silver Diamine Fluoride on Salivary Biofilm

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