Effects of Neutral Eohyeol(Yuxue) Herbal Acupuncture and Dangkisoo-san(Dangguixu-san) on Fracture Healing in the Early Stage in Rats (中性瘀血 藥鍼과 當歸鬚散이 흰쥐의 骨折初期 骨癒合에 미치는 영향)

안혜림; Misook Shin (신미숙); choi jin bong (최진봉); 김선종

Effects of Neutral Eohyeol(Yuxue) Herbal Acupuncture and Dangkisoo-san(Dangguixu-san) on Fracture Healing in the Early Stage in Rats

Journal of Korean Medicine Rehabilitation
Abbr : JKMR
2007, 17(1), pp.1-16
Publisher : The Korean Academy Of Oriental Rehabilitation Medicine
Research Area : Medicine and Pharmacy > Korean Medicine

안혜림 ¹, Misook Shin ², choi jin bong ³, 김선종 ³

¹동신대학교 목동한방병원
²부산대학교
³동신대학교

Candidate

ABSTRACT

Effects of Neutral Eohyeol(Yuxue) Herbal Acupuncture and Dangkisoo-san(Dangguixu-san) on Fracture Healing in the Early Stage in Rats Hye-Lim Ahn, O.M.D., Mi-Suk Shin, O.M.D., Sun-Jong Kim, O.M.D., Jin-Bong Choi, O.M.D. Dept. of Oriental Rehabilitation Medicine, Dong-Shin University Mok-Dong Oriental HospitalDept. of Oriental Rehabilitation Medicine, College of Oriental Medicine, Dong-Shin University* Objectives : This study was designed to evaluate the effects of Neutral Eohyeol(Yuxue) herbal acupuncture and Dangkisoo-san(Dangguixu-san) on fracture healing in rats. Methods : We divided the subjects into 5 groups : normal, control with no treatment, Sample Ⅰ taken with Dangkisoo-san(Dangguixu-san), Sample Ⅱ taken with Neutral Eohyeol(Yuxue) herbal acupuncture and sample Ⅲ taken with Neutral Eohyeol(Yuxue) herbal acupuncture and Dangkisoo-san(Dangguixu-san) groups. We induced penetrating fracture on femur in control, sample Ⅰ, Ⅱ and Ⅲ groups. And after serum T-ALP, serum osteocalcin, histological changes, and the degree of TGF-β1 in each group were observed at the 7th day and at the 14th day respectively. Results : All the sample groups showed significant changes in serum T-ALP, histological observation and TGF-beta 1 compared with control group. Especially sample Ⅲ was more effective than other groups in fracture healing. However, serum osteocalcin insignificantly increased at the 14th day. It seemed that 14 day was too short to evaluate osteocalcin. Conclusions : It is suggested that Neutral Eohyeol(Yuxue) herbal acupuncture and Dangkisoo-san(Dangguixu-san) may play a significant role in fracture healing and these two treatments could be more effective when used together.

KEYWORDS

Neutral Eohyeol(Yuxue) herbal acupuncture, Dangkisoo-san(Dangguixu-san), Fracture

Citation status

* References for papers published after 2023 are currently being built.

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