@article{ART001179367},
author={한주원 and Minseok Oh and Yoon il ji and 송영일},
title={Inhibitory Effect of Kuseupbokhap-bang on (Qùshīfùhé-fāng)Rheumatoid Arthritis in Human Fibroblast-like Synoviocytes},
journal={Journal of Korean Medicine Rehabilitation},
issn={1229-1854},
year={2006},
volume={16},
number={3},
pages={1-16}
TY - JOUR
AU - 한주원
AU - Minseok Oh
AU - Yoon il ji
AU - 송영일
TI - Inhibitory Effect of Kuseupbokhap-bang on (Qùshīfùhé-fāng)Rheumatoid Arthritis in Human Fibroblast-like Synoviocytes
JO - Journal of Korean Medicine Rehabilitation
PY - 2006
VL - 16
IS - 3
PB - The Korean Academy Of Oriental Rehabilitation Medicine
SP - 1
EP - 16
SN - 1229-1854
AB - Objectives :
This study was carried out to know the inhibitory effect of Kuseupbokhap-bang(Qùshīfùhé-fāng; KC) on rheumatoid arthritis in human fibroblast-like synoviocytes(hFLSs).
Methods :
For this purpose, experiments were performed to measure the cytotoxicity against hFCs and the production of pro-inflammatory cytokines in hFLSs and the production of NO, ROS.
Results :
KC had no cytotoxicity against hFCs and reduced the production of pro-inflammatory cytokines TNF-α, IL-6, IL-8, IL-1β in hFLSs, increased the production of TIMP-1. As well as KC reduced the production of MMP-3, NOS-II, ICAM-1, the production of Nitric oxide and ROS, and the proliferation of hFLSs in proportion to the concentration of KC significantly.
Conclusions :
Comparison of the results for this study showed that KC had immunomodulatory effects of suppressing or enhancing.
KW - Kuseupbokhap-bang(Qshfh-fng);Rheumatoid arthritis;Immunomodulatory;Immunity;Collagen-induced arthritis(CIA) mice.
DO -
UR -
ER -
한주원, Minseok Oh, Yoon il ji and 송영일. (2006). Inhibitory Effect of Kuseupbokhap-bang on (Qùshīfùhé-fāng)Rheumatoid Arthritis in Human Fibroblast-like Synoviocytes. Journal of Korean Medicine Rehabilitation, 16(3), 1-16.
한주원, Minseok Oh, Yoon il ji and 송영일. 2006, "Inhibitory Effect of Kuseupbokhap-bang on (Qùshīfùhé-fāng)Rheumatoid Arthritis in Human Fibroblast-like Synoviocytes", Journal of Korean Medicine Rehabilitation, vol.16, no.3 pp.1-16.
한주원, Minseok Oh, Yoon il ji, 송영일 "Inhibitory Effect of Kuseupbokhap-bang on (Qùshīfùhé-fāng)Rheumatoid Arthritis in Human Fibroblast-like Synoviocytes" Journal of Korean Medicine Rehabilitation 16.3 pp.1-16 (2006) : 1.
한주원, Minseok Oh, Yoon il ji, 송영일. Inhibitory Effect of Kuseupbokhap-bang on (Qùshīfùhé-fāng)Rheumatoid Arthritis in Human Fibroblast-like Synoviocytes. 2006; 16(3), 1-16.
한주원, Minseok Oh, Yoon il ji and 송영일. "Inhibitory Effect of Kuseupbokhap-bang on (Qùshīfùhé-fāng)Rheumatoid Arthritis in Human Fibroblast-like Synoviocytes" Journal of Korean Medicine Rehabilitation 16, no.3 (2006) : 1-16.
한주원; Minseok Oh; Yoon il ji; 송영일. Inhibitory Effect of Kuseupbokhap-bang on (Qùshīfùhé-fāng)Rheumatoid Arthritis in Human Fibroblast-like Synoviocytes. Journal of Korean Medicine Rehabilitation, 16(3), 1-16.
한주원; Minseok Oh; Yoon il ji; 송영일. Inhibitory Effect of Kuseupbokhap-bang on (Qùshīfùhé-fāng)Rheumatoid Arthritis in Human Fibroblast-like Synoviocytes. Journal of Korean Medicine Rehabilitation. 2006; 16(3) 1-16.
한주원, Minseok Oh, Yoon il ji, 송영일. Inhibitory Effect of Kuseupbokhap-bang on (Qùshīfùhé-fāng)Rheumatoid Arthritis in Human Fibroblast-like Synoviocytes. 2006; 16(3), 1-16.
한주원, Minseok Oh, Yoon il ji and 송영일. "Inhibitory Effect of Kuseupbokhap-bang on (Qùshīfùhé-fāng)Rheumatoid Arthritis in Human Fibroblast-like Synoviocytes" Journal of Korean Medicine Rehabilitation 16, no.3 (2006) : 1-16.