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Effects of Kyungohkgo(Qiong yu gao) on Growth and Learning Ability in Growth Deficiency Rat with Insufficient Nutrition Diet

  • Journal of Korean Medicine Rehabilitation
  • Abbr : JKMR
  • 2008, 18(2), pp.97-109
  • Publisher : The Korean Academy Of Oriental Rehabilitation Medicine
  • Research Area : Medicine and Pharmacy > Korean Medicine

한석훈 1 Cha Yun Yeop 1 Lee,Eun 1

1상지대학교

Accredited

ABSTRACT

Objectives : Effects of Kyungohkgo(Qióng yù gào) on intellectual development and learning ability were investigated growth and intellectual impairment rat with insufficient nutrition diet. Methods : We divided male Sprague-Dawley rats into 4 groups(A, B, C, D). They were normal group(A), growth deficiency rat with insufficient nutrition diet group(B), growth deficiency rat with 0.1% Kyungohkgo(Qióng yù gào) group(C) and growth deficiency rat with 0.2% Kyungohkgo(Qióng yù gào) group(D). They were administered for 5 weeks. We measured body weight, serum growth hormone, insulin-like growth factor and thyroid stimulating hormone, RBC, concentration of Hb and PCV ratio, total WBC and its composition, the values of plasma glutamic oxaloacetic transaminase(GOT) and glutamic pyruvic transaminase(GPT) activities and morris water maze test in escape distance, escape time and escape speed. Results : 1. Body weight showed a tendency to increase in the Kyungohkgo(Qióng yù gào) groups and 0.2% Kyungohkgo(Qióng yù gào) group showed significantly different than control groups. 2. Serum growth hormone, insulin-like growth factor and thyroid stimulating hormone showed a tendency to increase in Kyungohkgo(Qióng yù gào) groups, however these values showed no significantly different. 3. About the counts of RBC, 0.1% and 0.2% Kyungohkgo(Qióng yù gào) groups showed significantly different than control groups. Concentration of Hb was higher than control group in Kyungohkgo(Qióng yù gào) groups. And 0.2% Kyungohkgo(Qióng yù gào) group showed significantly different than control groups in PCV ratio. 4. The counts of total WBC and its composition showed no significantly different in all treatment groups. 5. The values of plasma glutamic oxaloacetic transaminase(GOT) and glutamic pyruvic transaminase(GPT) activities showed no significantly different in all treatment groups. 6. In the morris water maze test, in escape distance and escape speed, Kyungohkgo(Qióng yù gào) groups showed no significantly different than control group. But Kyungohkgo(Qióng yù gào) groups showed the increasing tendency. Conclusions : So Kyungohkgo(Qióng yù gào) have an effect of promoting growth of rats and might be effect to treat various kinds of growth delay in children.

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