@article{ART001244152},
author={공상은 and Minseok Oh},
title={The Experimental Effect of Haedongpibokhap-bang (Haitongpifuhe-fang) on Collagen-induced Arthritisgroup. So, further studies will be needed.},
journal={Journal of Korean Medicine Rehabilitation},
issn={1229-1854},
year={2008},
volume={18},
number={2},
pages={1-15}
TY - JOUR
AU - 공상은
AU - Minseok Oh
TI - The Experimental Effect of Haedongpibokhap-bang (Haitongpifuhe-fang) on Collagen-induced Arthritisgroup. So, further studies will be needed.
JO - Journal of Korean Medicine Rehabilitation
PY - 2008
VL - 18
IS - 2
PB - The Korean Academy Of Oriental Rehabilitation Medicine
SP - 1
EP - 15
SN - 1229-1854
AB - Objectives :
The aim of this study was to know the immuity response of Haedongpibokhap-bang(Haitongpifuhe-fang) to rheumatoid arthritis in collagen-induced arthritis(CIA) mice.
Methods :
For this purpose, Haedongpibokhap-bang(Haitongpifuhe-fang) was orally administerd to mice with arthritis induced by collagen Ⅱ and then value of immunocyte in spleen, draining lymph node and paw joint and cytokine(IL-6, TNF-α), rheumatoid factor (IgG and IgM) in serum were measured.
Results :
1. The arthritis index was significantly decreased.
2. In total cell counts of spleen, DLN and paw joint, the cells in spleen decreased while there was a significant increase in DLN and significant decrease in paw joint.
3. In lymph nodes, CD3+, CD3+/CD69+, CD4+, CD8+ cells increased significantly.
4. In joints, CD3+ and CD11+b/Gr-1+ cells decreased significantly.
5. Serum IL-6 and TNF-α were decreased significantly.
6. Production of serum IgG and IgM decreased significantly.
Conclusions :
The results present that Haedongpibokhap-bang(Haitongpifuhe-fang) controls abnormal activity of immune system, inhibitig collagen-induced arthritis(CIA).
KW - Haedongpibokhap-bang(Haitongpifuhe-fang);Rheumatoid arthritis;CIA;Immunocyte;Cytokine;Rheumatoid factor
DO -
UR -
ER -
공상은 and Minseok Oh. (2008). The Experimental Effect of Haedongpibokhap-bang (Haitongpifuhe-fang) on Collagen-induced Arthritisgroup. So, further studies will be needed.. Journal of Korean Medicine Rehabilitation, 18(2), 1-15.
공상은 and Minseok Oh. 2008, "The Experimental Effect of Haedongpibokhap-bang (Haitongpifuhe-fang) on Collagen-induced Arthritisgroup. So, further studies will be needed.", Journal of Korean Medicine Rehabilitation, vol.18, no.2 pp.1-15.
공상은, Minseok Oh "The Experimental Effect of Haedongpibokhap-bang (Haitongpifuhe-fang) on Collagen-induced Arthritisgroup. So, further studies will be needed." Journal of Korean Medicine Rehabilitation 18.2 pp.1-15 (2008) : 1.
공상은, Minseok Oh. The Experimental Effect of Haedongpibokhap-bang (Haitongpifuhe-fang) on Collagen-induced Arthritisgroup. So, further studies will be needed.. 2008; 18(2), 1-15.
공상은 and Minseok Oh. "The Experimental Effect of Haedongpibokhap-bang (Haitongpifuhe-fang) on Collagen-induced Arthritisgroup. So, further studies will be needed." Journal of Korean Medicine Rehabilitation 18, no.2 (2008) : 1-15.
공상은; Minseok Oh. The Experimental Effect of Haedongpibokhap-bang (Haitongpifuhe-fang) on Collagen-induced Arthritisgroup. So, further studies will be needed.. Journal of Korean Medicine Rehabilitation, 18(2), 1-15.
공상은; Minseok Oh. The Experimental Effect of Haedongpibokhap-bang (Haitongpifuhe-fang) on Collagen-induced Arthritisgroup. So, further studies will be needed.. Journal of Korean Medicine Rehabilitation. 2008; 18(2) 1-15.
공상은, Minseok Oh. The Experimental Effect of Haedongpibokhap-bang (Haitongpifuhe-fang) on Collagen-induced Arthritisgroup. So, further studies will be needed.. 2008; 18(2), 1-15.
공상은 and Minseok Oh. "The Experimental Effect of Haedongpibokhap-bang (Haitongpifuhe-fang) on Collagen-induced Arthritisgroup. So, further studies will be needed." Journal of Korean Medicine Rehabilitation 18, no.2 (2008) : 1-15.