@article{ART001385997},
author={김용걸 and Minseok Oh},
title={The Inhibitory Effects of Gambibang-3 on the Obese-Mice Induced by High-Fat Diet},
journal={Journal of Korean Medicine Rehabilitation},
issn={1229-1854},
year={2009},
volume={19},
number={4},
pages={79-94}
TY - JOUR
AU - 김용걸
AU - Minseok Oh
TI - The Inhibitory Effects of Gambibang-3 on the Obese-Mice Induced by High-Fat Diet
JO - Journal of Korean Medicine Rehabilitation
PY - 2009
VL - 19
IS - 4
PB - The Korean Academy Of Oriental Rehabilitation Medicine
SP - 79
EP - 94
SN - 1229-1854
AB - Objectives :
In order to investigate the effects of Gambibang-3(here in after referred to GBB3) on the obese gene and obese inhibitory, C57BL/6 mice were induced by high fat diet.
Methods :
C57BL/6 mice were divided into four groups(normal, high fat diet with control, high fat diet with Reductil(here in after referred to RDT), high fat diet with GBB3 extract) and fed for 8 weeks. And observed that, the weight change of the adipocytes in body and liver, total cholesterol, LDL-cholesterol, HDL-cholesterol, triglyceride, glucose, leptin change in the serum, the expression of β3AR and leptin gene in 3T3 cell and primary adipocyte cell.
Results & conclusions :
The following results were obtained in this study.
1. GBB3 and RDT group showed that the revelation of β3AR in primary adipose cell and 3T3 cell were increased considerably, and that the revelation of leptin in primary adipose cell and 3T3 cell were decreased considerably.
2. GBB3 and RDT group showed that the weight of adipocyte and liver were not different with control group significantly.
3. GBB3 and RDT group showed that the amount of HDL-Cholesterol were increased considerably, the amount of glucose, LDL-Cholesterol and Triglyceride were decreased considerably.
4. GBB3 group showed that the amount of leptin in the serum were decreased considerably.
KW - Gambibang-3(GBB3);Obese gene;Obese inhibitory;Adipocyte;Liver tissue
DO -
UR -
ER -
김용걸 and Minseok Oh. (2009). The Inhibitory Effects of Gambibang-3 on the Obese-Mice Induced by High-Fat Diet. Journal of Korean Medicine Rehabilitation, 19(4), 79-94.
김용걸 and Minseok Oh. 2009, "The Inhibitory Effects of Gambibang-3 on the Obese-Mice Induced by High-Fat Diet", Journal of Korean Medicine Rehabilitation, vol.19, no.4 pp.79-94.
김용걸, Minseok Oh "The Inhibitory Effects of Gambibang-3 on the Obese-Mice Induced by High-Fat Diet" Journal of Korean Medicine Rehabilitation 19.4 pp.79-94 (2009) : 79.
김용걸, Minseok Oh. The Inhibitory Effects of Gambibang-3 on the Obese-Mice Induced by High-Fat Diet. 2009; 19(4), 79-94.
김용걸 and Minseok Oh. "The Inhibitory Effects of Gambibang-3 on the Obese-Mice Induced by High-Fat Diet" Journal of Korean Medicine Rehabilitation 19, no.4 (2009) : 79-94.
김용걸; Minseok Oh. The Inhibitory Effects of Gambibang-3 on the Obese-Mice Induced by High-Fat Diet. Journal of Korean Medicine Rehabilitation, 19(4), 79-94.
김용걸; Minseok Oh. The Inhibitory Effects of Gambibang-3 on the Obese-Mice Induced by High-Fat Diet. Journal of Korean Medicine Rehabilitation. 2009; 19(4) 79-94.
김용걸, Minseok Oh. The Inhibitory Effects of Gambibang-3 on the Obese-Mice Induced by High-Fat Diet. 2009; 19(4), 79-94.
김용걸 and Minseok Oh. "The Inhibitory Effects of Gambibang-3 on the Obese-Mice Induced by High-Fat Diet" Journal of Korean Medicine Rehabilitation 19, no.4 (2009) : 79-94.
