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The Effect of the Ethanol Extracts from Lythrum Salicaria L. and Aceriphyllum Rossii on the Body Composition and Temperature of Overweight and Obese Adults - a randomized, double blinded, two arm, placebo food controlled, single center, preliminary human study -

  • Journal of Korean Medicine Rehabilitation
  • Abbr : JKMR
  • 2012, 22(3), pp.25-36
  • Publisher : The Korean Academy Of Oriental Rehabilitation Medicine
  • Research Area : Medicine and Pharmacy > Korean Medicine

이동은 1 박원형 2 Cha Yun Yeop 2

1상지대학교 한의과대학 한방재활의학과교실
2상지대학교

Accredited

ABSTRACT

bjectives :The aim of this study was to examine the effect of the ethanol extracts from Lythrum salicaria and Aceriphyllum rossii on the body composition and temperature of overweight and obese adults. Methods :This study, which was approved by IRB(institutional review board), was conducted on a total of 50 male and female subjects between the ages of 19 and 60 with a body mass index(BMI) of 23.0 kg/m2 to 29.9 kg/m2. Voluntary consent was obtained from the subjects, who were then randomly assigned to a treatment group(25 subjects) and a placebo group(25 subjects). Ethanol extracts from lythrum salicaria and aceriphyllum rossii and placebo food were orally administered to the treatment group and the placebo group, respectively, at an equal dosage of four 500 mg capsules three times a day for 8 weeks. During the testing, 8 subjects from each group were eliminated, and a total of 34 subjects completed the testing. Measurements of the surface areas of intestinal and subcutaneous fat using the abdominal computed tomography(CT) scan, measurements of the limbs and torso, and assessment of abdominal body temperature using digital infrared thermographic imaging(DITI) were conducted before and after the testing. Results :When the area of fat was measured using the abdominal CT scan before and after the testing group, a difference was observed within the placebo group, but not within the treatment group. The circumference of the limbs and torso measured through the body composition test performed before and after the testing showed no difference within either group. An intragroup comparison through infrared thermographic imaging showed no significant difference within the placebo group, but showed difference in the middle abdomen area in the treatment group. There were no significant difference between the two groups in the comparison of body temperature, CT scan and the circumference of the limbs and torso measured through the body composition test performed between before and after the testing. Conclusions :The treatment group administered the ethanol extracts from Lythrum salicaria and aceriphyllum rossii showed no significant difference in terms of body composition and body temperature compared to the placebo group.

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