2012, Vol.22, No.3

The Enhancing Effects of Gwibi-tang(guīpí-tāng) on Cognitive Function and Memory in Scopolamine-induced Dementia Rat Model

김정원 , Kim Seon Jong | 2012, 22(3) | pp.1~14 | number of Cited : 7

Objectives :The purpose of this experiment was designed to investigate the effects of Gwibi-tang(guīpí-tāng), which has been traditionally used for treatment of psychologic disease and brain damage in oriental medicine, on dementia induced by scopolamine in the rats. Methods : Groups were divided into 4 groups: Normal group, control group, positive control group(tacrine group) and Gwibi-tang(guīpí-tāng) group. Control group :To induce dementia, 1 mg/kg of Scopolamine intraperitoneal injection is used for 14 days(1 per day) in the rats. Positive control group(tacrine group): 10 mg/kg of tacrine, the dementia treatment, is medicated in oral inoculation. After 30 mintues, 1 mg/kg of scopolamine intraperitoneal injection, which causes dementia, is used for 14 days(1 per day). Gwibi-tang(guīpí-tāng) group: 300 mg/kg of Gwibi-tang(guīpí-tāng) is medicated in oral inoculation. After 30 mintues, 1 mg/kg of scopolamine intraperitoneal injection, which causes dementia, is used for 14 days(1 per day). The present author observed the passive avoidance performance test, the spatial learning and memory ability test(Morris water maze test), the values of acetylcholine(ACh), acetylcholin esterase(AchE) activity in the hippocampal, the cerebral cortex. Results : 1. In passive avoidance test on 1st day and 3rd day of causing dementia, Gwibi-tang(guīpí-tāng) group appeared to be more significant than positive control group. On 7th day and 14th day, Gwibi-tang(guīpí-tāng) group appeared to be more significant than normal control group and control group. However, there was no significant difference between Gwibi-tang(guīpí-tāng) group and positive control group. 2. In a test of spatial learning and memory ability, on 7th day and 14th day of causing dementia, Gwibi-tang(guīpí-tāng) group and positive control group appeared to be more significant more than control group. There was no significant difference between Gwibi-tang(guīpí-tāng) group and positive control group. 3. In Ach and AchE activity test, Ach and AchE activity in brain system and the hippocampal, cerebral cortex appeared to be more significant in Gwibi-tang(guīpí-tāng) group and positive control group than control group. However, there was no significant difference between Gwibi-tang(guīpí-tāng) group and positive control group. 4. In liver and kidney tissue tests, all experimental group appeared to be normal. which indicates that Gwibi-tang(gul̄plˊ-tāng) does not damage liver and kidney. From the results above, Gwibi-tang(guīpí-tāng) is thought to be effective in improvement of memory related to cholinergic nerve problem and dementia. Conclusions : The present author thought that Gwibi-tang(guīpí-tāng) might be usefully applied for prevention and treatment of dementia and memory disorder. Further study is needed to conduct a rigorous clinical research.

A Study on the Effect of EST on Trunk Flexors and Extensors

Jae-Hwa Shin , 최보미 , 김현수 and 1 other persons | 2012, 22(3) | pp.15~23 | number of Cited : 0

The Effect of the Ethanol Extracts from Lythrum Salicaria L. and Aceriphyllum Rossii on the Body Composition and Temperature of Overweight and Obese Adults - a randomized, double blinded, two arm, placebo food controlled, single center, preliminary human study -

이동은 , 박원형 , Cha Yun Yeop | 2012, 22(3) | pp.25~36 | number of Cited : 2

bjectives :The aim of this study was to examine the effect of the ethanol extracts from Lythrum salicaria and Aceriphyllum rossii on the body composition and temperature of overweight and obese adults. Methods :This study, which was approved by IRB(institutional review board), was conducted on a total of 50 male and female subjects between the ages of 19 and 60 with a body mass index(BMI) of 23.0 kg/m2 to 29.9 kg/m2. Voluntary consent was obtained from the subjects, who were then randomly assigned to a treatment group(25 subjects) and a placebo group(25 subjects). Ethanol extracts from lythrum salicaria and aceriphyllum rossii and placebo food were orally administered to the treatment group and the placebo group, respectively, at an equal dosage of four 500 mg capsules three times a day for 8 weeks. During the testing, 8 subjects from each group were eliminated, and a total of 34 subjects completed the testing. Measurements of the surface areas of intestinal and subcutaneous fat using the abdominal computed tomography(CT) scan, measurements of the limbs and torso, and assessment of abdominal body temperature using digital infrared thermographic imaging(DITI) were conducted before and after the testing. Results :When the area of fat was measured using the abdominal CT scan before and after the testing group, a difference was observed within the placebo group, but not within the treatment group. The circumference of the limbs and torso measured through the body composition test performed before and after the testing showed no difference within either group. An intragroup comparison through infrared thermographic imaging showed no significant difference within the placebo group, but showed difference in the middle abdomen area in the treatment group. There were no significant difference between the two groups in the comparison of body temperature, CT scan and the circumference of the limbs and torso measured through the body composition test performed between before and after the testing. Conclusions :The treatment group administered the ethanol extracts from Lythrum salicaria and aceriphyllum rossii showed no significant difference in terms of body composition and body temperature compared to the placebo group.

Analysis of Persistent Pollutants in Supplied Korea Traditional Medical Materials at Oriental Medical Hospital of Sangji University

이용현 , Cha Yun Yeop , EunMee Lim and 1 other persons | 2012, 22(3) | pp.37~47 | number of Cited : 0

Effects of Yukmijihwang-tang(Liuweidihuang-tang ) and Cervi Pantotrichum Cornu Pharmacopuncture on Fracture Healing in Diabetic Rats

기영범 , 김대훈 , 강대희 and 2 other persons | 2012, 22(3) | pp.49~63 | number of Cited : 8

Objectives :This study was designed to evaluate the effects of Yukmijihwang-tang(Liuweidihuang-tang) and Cervi Pantotrichum Cornu pharmacopuncture on fracture healing in diabetic rats. Methods :In this study, 80 Sprague-Dawley rats were induced by STZ(streptozotocin) which was in general use as diabetes model. After the subjects were induced femur fracture, we divided the subjects into 4 groups : Control group with no treatment, experimental Ⅰ taken with Yukmijihwang-tang(Liuweidihuang-tang), experimental Ⅱ taken with Cervi Pantotrichum Cornu pharmacopuncture and experimental Ⅲ taken with Yukmijihwang-tang(Liuweidihuang-tang) and Cervi Pantotrichum Cornu pharmacopuncture groups. Serum T-ALP(total alkaline phosphatase), histological observation of callus formation, and the degree of TGF-β1(transforming growth factor beta 1) in each group were observed at the 7th, 14th, 21th day and at the 28th day respectively. Results :1. Experimental group Ⅰ and experimental group Ⅲ showed significant changes in serum T-ALP after 7-days of experimental period. All the experimental groups showed significant changes in serum T-ALP after 14-days of experimental period, especially experimental group Ⅲ showed more significant changes than other groups. 2. After 14-days, 21-days and 28-days, all the experimental groups showed significant changes in histological observation of callus formation, compared with control group. Especially experimental group Ⅲ showed more significant changes than other groups. 3. All the experimental groups showed significant changes in TGF-β1 compared with control group. Especially experimental group Ⅲ showed more significant changes than other groups. 4. Injury of liver tissue and kidney tissue in histological findings were not seen after 28-days of experimental period. Conclusions :It is suggested that Yukmijihwang-tang(Liuweidihuang-tang) and Cervi Pantotrichum Cornu pharmacopuncture may play a significant role in fracture healing in diabetic rats, and these two treatments could be more effective when used together.

Effects of Ethanol Extract from Sodok -eum on UVB-induced Damage in Human Keratinocyte HaCaT Cells

전규상 , 김일현 , 임광묵 and 1 other persons | 2012, 22(3) | pp.65~78 | number of Cited : 1

Narrative Review of Clinical Trial on Hominis Placenta Pharmacopuncture in Korean Literature

이진현 , Dong-Chan Jo , 문수정 and 5 other persons | 2012, 22(3) | pp.79~88 | number of Cited : 12

Trend Analysis about New Health Technologies Notified by Ministry of Health & Welfare : Focused on Traditional Korean Medicine

박황진 , Ohmin Kwon , Lee Bong Hyo and 2 other persons | 2012, 22(3) | pp.89~100 | number of Cited : 3

A Literature Review on the Clinical Application of Muscle Energy Techniques(MET) : Reviewing Domestic and International Articles Published after Year 2000

최효정 , Chang-Ho Yeon , Sang Min Lee and 2 other persons | 2012, 22(3) | pp.101~115 | number of Cited : 1

Experience of Low Back Pain in Bone-arrangement Therapy : A Qualitative Study

BoKyung Yim , Park， In Sook , Jeong-Hwa Lee and 2 other persons | 2012, 22(3) | pp.117~131 | number of Cited : 2

The Study on Correlation between the Lumbar Lordosis and the Spinal Alignment Deformation

김형길 , Cha Yun Yeop , 박원형 | 2012, 22(3) | pp.133~140 | number of Cited : 2

The Effects of Ultrasonic Lipolysis Treatment on Obesity Compared to Electroacupuncture

Ji-Young Kim , Kim， Soon-joong , Jeong， Su-hyeon | 2012, 22(3) | pp.141~149 | number of Cited : 5

The Effect of Sling Exercise Therapy and Motor Control Exercise on Pain, ADL Performance and Trunk Muscle Strength in Patients with Chronic Low Back Pain

하영신 , Jongsoo Lee , 김성식 and 1 other persons | 2012, 22(3) | pp.151~162 | number of Cited : 10

Objectives :This study was to determine the effects of a sling exercise therapy and motor control exercise program on pain, disability and lumbar strength in patients with chronic low back pain. Methods :24 subjects who were in the patients with chronic low back pain were randomly divided into two groups for trunk muscle training: with sling exercise group(n=12), and motor control exercise group(n=12). but 4 subjects were left out of this study, finally 9 and 11 in each group respectively. All groups were given four-week conventional physical therapy, which was conducted 40 minutes per day, 2 times per week over a 4 week period. sling exercise subjects received Sling exercise program for 40 minutes per day, 2 times per week over a 4 week period. motor control exercise subjects received motor control exercise program for 40 minutes per day, 2 times per week over a 4 week period. Pain, disability and trunk muscle strength are measured to identify the effect of the sling exercise and motor control exercise. Results :For the low back pain, the level of visual analogue scale(VAS) were significantly decreased after compared to before the intervention within sling exercise group and motor control exercise group(p<0.05). For the disability, the level of Oswestry disability index(ODI) were significantly decreased after compared to before the intervention within sling exercise group and motor control exercise group(p<0.05). For the trunk muscle strength were significantly decreased after compared to before the intervention within sling exercise group and motor control exercise group(p<0.05). There was significant pain relief, improvement of disability and trunk muscle strengthening in both group(p<0.05) after 4 weeks. Conclusions :These findings indicate that the both interventions may release pain and improve ADL performance and trunk muscle strength in patients with chronic low back pain.

The Correlation among Neck Pain, Temporomandibular Pain and Headache in Patients with Neck Pain

양요찬 , 송은모 , Kim Koh-Woon and 2 other persons | 2012, 22(3) | pp.163~171 | number of Cited : 2

An Analysis of Comparison between Wet Cupping with Dry Cupping - On Acute Cervical and Lumbar Sprain Patients by Traffic Accident -

이형은 , Dongseok Heo | 2012, 22(3) | pp.173~192 | number of Cited : 2

The Comparison of Superficial and Deep Acupuncture on the Ashi-point of Elbow Pain Patients

이상민 , Jongsoo Lee | 2012, 22(3) | pp.193~203 | number of Cited : 2

Objectives :The purpose of this study was to compare the effect of superficial acupuncture to deep acupuncture on finger extensor muscle function. Methods :We included 22 participants who met the inclusion criteria and assigned them into two groups after the randomization. We allocated 11 people in the superficial acupuncture treatment group and the deep acupuncture treatment group. We used 0.25 mm×40 cm needle made by stainless steel. In superficial acupuncture treatment group, 11 subjects had been treated by superficial acupuncture(2 mm) on finger extensor muscle. In deep acupuncture treatment group, 11 healthy subjects had been treated by deep acupuncture(10 mm). Each session took 15 minutes. Before and after the treatment, outcomes were assessed by algometer for muscle tenderness, VAS(visual analog scale) for bothersomeness and pain, dynamometer for grasping power and meridian-electromyograph(MEMG) for finger extensor muscles, heart rate variation(HRV). Results :There was a significant increase in the pressure pain threshold of the finger extensor muscle in the superficial acupuncture compare to deep acupuncture at before-after treatment comparison. There was a significant increase in the pressure pain threshold of the finger extensor muscle in the deep acupuncture compare to superficial acupuncture at end point comparison. There was a significant reduction in LF(low frequency power)/HF(high frequency power) ratio in the deep acupuncture group. There was a significant increase in Ln(natural logarithm) HF, LF/HF ratio in the deep acupuncture compare to superficial acupuncture at end point comparison. Conclusions :According to above results, superficial acupuncture tend to more effective on reducing pressure pain threshold and VAS for pain in immediate treatment. deep acupuncture tend to more effective on muscle function and power in long-term treatment.

A Study on Clinical Effectiveness for the Osteoarthritis of Knee Joint Between Acupuncture group and Acupuncture Plus TDP(Tending Diancibo Pu)

어봉우 , 허혁 | 2012, 22(3) | pp.205~213 | number of Cited : 1

A Case Report of Eyelid Ptosis Caused by Oculomotor Nerve Palsy after Traumatic Epidural Hemorrhage Treated with Press Needle

이성준 , 김병정 , 박국지 and 1 other persons | 2012, 22(3) | pp.215~224 | number of Cited : 2

Two Case Studies on the Patients Suffer from Referral Retro-orbital Pain by Splenius Cervicis Muscle

황은미 , 박영희 , Keum Dong-ho | 2012, 22(3) | pp.225~234 | number of Cited : 1

Oriental Medicine Treatment for Common Peroneal Neuropathy after Traffic Acidents; 2 cases report

Dong-Chan Jo , 임광묵 , 이진현 and 6 other persons | 2012, 22(3) | pp.235~242 | number of Cited : 5

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Journal of Korean Medicine Rehabilitation 2023 KCI Impact Factor : 0.6

2012, Vol.22, No.3