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@article{ART001846475},
author={박수곤 and 배길준 and 이욱재 and Kim Seon Jong and 정민영},
title={The Effects of Bambusae caulis in liquamen and Bambusae concretio silicaeon Blood Sugar Reduction and Improvement of Peripheral Nerve Function in Diabetic Rats Induced with Streptozotocin},
journal={Journal of Korean Medicine Rehabilitation},
issn={1229-1854},
year={2014},
volume={24},
number={1},
pages={13-30}

TY - JOUR
AU - 박수곤
AU - 배길준
AU - 이욱재
AU - Kim Seon Jong
AU - 정민영
TI - The Effects of Bambusae caulis in liquamen and Bambusae concretio silicaeon Blood Sugar Reduction and Improvement of Peripheral Nerve Function in Diabetic Rats Induced with Streptozotocin
JO - Journal of Korean Medicine Rehabilitation
PY - 2014
VL - 24
IS - 1
PB - The Korean Academy Of Oriental Rehabilitation Medicine
SP - 13
EP - 30
SN - 1229-1854
AB - Objectives This study was designed to investigate the effects of Bambusae caulis in liquamen and Bambusae concretio silicae on blood sugar reduction and improvement of peripheral nerve function in diabetic rat models. Methods Diabetic rat models induced by streptozotocin were divided into five groups. We fed experimental group I of rats basal diet and administered normal saline (3 ml, 1 time/1 day) for 6 weeks. We fed experimental group II of rats basal diet and administered Bambusae caulis in liquamen (100 mg/kg, 1 time/1 day) for 6 weeks. We fed experimental group III, IV, V of rats basal diet and administered Bambusae concretio silicae (100 mg/kg, 200 mg/kg, 400 mg/kg once a day) for 6 weeks. We investigated weight and glucose level of rats, and carried out touch test, hot plate test, sensory ＆ motor nerve conduction velocity test and immunohistochemical study after 48 hours, 2 weeks, 4 weeks and 6 weeks. Results 1. The weight of all experimental group was gradually decreased. And glucose level was significantly decreased in the experimental group II, III, IV, V as compared with experimental group I. Especially experimental group II, IV, V were significantly decreased as compared with experimental group III. 2. In the quantitative analysis by touch test and hot plate test, mechanical pain threshold and heat pain threshold were significantly decreased in the other experimental groups as compared with experimental group I. Especially experimental group II, IV, V were significantly decreased as compared with experimental group III. 3. In the sensory and motor nerve conduction velocity test, sensory and motor nerve conduction velocity were significantly increased in the other experimental groups as compared with experimental group I. Especially experimental group II, IV, V were significantly increased as compared with experimental group III. 4. In the substance P immunohistochemical study, experimental group II, IV, V showed strong immune response in spinal cord. Conclusions Bambusae caulis in liquamen and Bambusae concretio silicae were probably useful to treat patients with diabetic peripheral neuropathy.
KW - Bambusae caulis in liquamen;Bambusae concretio silicae;Diabetic periph-eral neuropathy;Peripheral nerve function
DO -
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ER -

박수곤, 배길준, 이욱재, Kim Seon Jong and 정민영. (2014). The Effects of Bambusae caulis in liquamen and Bambusae concretio silicaeon Blood Sugar Reduction and Improvement of Peripheral Nerve Function in Diabetic Rats Induced with Streptozotocin. Journal of Korean Medicine Rehabilitation, 24(1), 13-30.

박수곤, 배길준, 이욱재, Kim Seon Jong and 정민영. 2014, "The Effects of Bambusae caulis in liquamen and Bambusae concretio silicaeon Blood Sugar Reduction and Improvement of Peripheral Nerve Function in Diabetic Rats Induced with Streptozotocin", Journal of Korean Medicine Rehabilitation, vol.24, no.1 pp.13-30.

박수곤, 배길준, 이욱재, Kim Seon Jong, 정민영 "The Effects of Bambusae caulis in liquamen and Bambusae concretio silicaeon Blood Sugar Reduction and Improvement of Peripheral Nerve Function in Diabetic Rats Induced with Streptozotocin" Journal of Korean Medicine Rehabilitation 24.1 pp.13-30 (2014) : 13.

박수곤, 배길준, 이욱재, Kim Seon Jong, 정민영. The Effects of Bambusae caulis in liquamen and Bambusae concretio silicaeon Blood Sugar Reduction and Improvement of Peripheral Nerve Function in Diabetic Rats Induced with Streptozotocin. 2014; 24(1), 13-30.

박수곤, 배길준, 이욱재, Kim Seon Jong and 정민영. "The Effects of Bambusae caulis in liquamen and Bambusae concretio silicaeon Blood Sugar Reduction and Improvement of Peripheral Nerve Function in Diabetic Rats Induced with Streptozotocin" Journal of Korean Medicine Rehabilitation 24, no.1 (2014) : 13-30.

박수곤; 배길준; 이욱재; Kim Seon Jong; 정민영. The Effects of Bambusae caulis in liquamen and Bambusae concretio silicaeon Blood Sugar Reduction and Improvement of Peripheral Nerve Function in Diabetic Rats Induced with Streptozotocin. Journal of Korean Medicine Rehabilitation, 24(1), 13-30.

박수곤; 배길준; 이욱재; Kim Seon Jong; 정민영. The Effects of Bambusae caulis in liquamen and Bambusae concretio silicaeon Blood Sugar Reduction and Improvement of Peripheral Nerve Function in Diabetic Rats Induced with Streptozotocin. Journal of Korean Medicine Rehabilitation. 2014; 24(1) 13-30.

박수곤, 배길준, 이욱재, Kim Seon Jong, 정민영. The Effects of Bambusae caulis in liquamen and Bambusae concretio silicaeon Blood Sugar Reduction and Improvement of Peripheral Nerve Function in Diabetic Rats Induced with Streptozotocin. 2014; 24(1), 13-30.

박수곤, 배길준, 이욱재, Kim Seon Jong and 정민영. "The Effects of Bambusae caulis in liquamen and Bambusae concretio silicaeon Blood Sugar Reduction and Improvement of Peripheral Nerve Function in Diabetic Rats Induced with Streptozotocin" Journal of Korean Medicine Rehabilitation 24, no.1 (2014) : 13-30.