@article{ART001897291},
author={Chang-Hoon Woo and Yong Eun Lee and Seong-Soo Roh and Jae Soo Kim},
title={Acupuncture Effects of Fatty Mice Induced by High Fat Diet},
journal={Journal of Korean Medicine Rehabilitation},
issn={1229-1854},
year={2014},
volume={24},
number={3},
pages={1-9}
TY - JOUR
AU - Chang-Hoon Woo
AU - Yong Eun Lee
AU - Seong-Soo Roh
AU - Jae Soo Kim
TI - Acupuncture Effects of Fatty Mice Induced by High Fat Diet
JO - Journal of Korean Medicine Rehabilitation
PY - 2014
VL - 24
IS - 3
PB - The Korean Academy Of Oriental Rehabilitation Medicine
SP - 1
EP - 9
SN - 1229-1854
AB - Objectives The aim of this study was to investigate the effects of acupuncture on weight loss, food intake, lipid metabolism, adipogenesis.
Methods Four week-old C57BL/6J mice acclimatized to the laboratory environment for 1 week were allocated into four groups of 6~8 mice each: normal diet group, high fat diet group, high fat diet group and treated with acupuncture at HT7, high fat diet group and treated with acupuncture at ST36 for 90days. High fat diet group was used to control group.
Results 1) Body weight, food intake of the ST36, HT7 groups decreased compared with those of control group. ST36 group was more effective with body weight decrease, and HT7 group was more effective with food intake decrease. 2) NEFA, TG, TC, ALT, AST of the ST36, HT7 groups decreased compared with those of control group. ST36 group was more effective. 3) The expression of SREP-1c, SREBP-2 of the ST36 group decreased compared with those of control group. These decreased rates were statistically significant.
SREBP-2 of the HT7 group decreased significantly compared to the control group. 4) LXR, FAS, SCD of the ST36 group decreased significantly compared with control group. 5) p-ACC, HMGCR of the ST36 group decreased significantly compared with those of control group. HMGCR of the HT7 group decreased significantly compared with control group.
Conclusions These results suggest that ST36, HT7 acupuncture may be used prevent or treat the obesity induced by high fat diet.
KW - Acupuncture;ST36;HT7;Obesity;Lipid metabolism;Adipogenesis
DO -
UR -
ER -
Chang-Hoon Woo, Yong Eun Lee, Seong-Soo Roh and Jae Soo Kim. (2014). Acupuncture Effects of Fatty Mice Induced by High Fat Diet. Journal of Korean Medicine Rehabilitation, 24(3), 1-9.
Chang-Hoon Woo, Yong Eun Lee, Seong-Soo Roh and Jae Soo Kim. 2014, "Acupuncture Effects of Fatty Mice Induced by High Fat Diet", Journal of Korean Medicine Rehabilitation, vol.24, no.3 pp.1-9.
Chang-Hoon Woo, Yong Eun Lee, Seong-Soo Roh, Jae Soo Kim "Acupuncture Effects of Fatty Mice Induced by High Fat Diet" Journal of Korean Medicine Rehabilitation 24.3 pp.1-9 (2014) : 1.
Chang-Hoon Woo, Yong Eun Lee, Seong-Soo Roh, Jae Soo Kim. Acupuncture Effects of Fatty Mice Induced by High Fat Diet. 2014; 24(3), 1-9.
Chang-Hoon Woo, Yong Eun Lee, Seong-Soo Roh and Jae Soo Kim. "Acupuncture Effects of Fatty Mice Induced by High Fat Diet" Journal of Korean Medicine Rehabilitation 24, no.3 (2014) : 1-9.
Chang-Hoon Woo; Yong Eun Lee; Seong-Soo Roh; Jae Soo Kim. Acupuncture Effects of Fatty Mice Induced by High Fat Diet. Journal of Korean Medicine Rehabilitation, 24(3), 1-9.
Chang-Hoon Woo; Yong Eun Lee; Seong-Soo Roh; Jae Soo Kim. Acupuncture Effects of Fatty Mice Induced by High Fat Diet. Journal of Korean Medicine Rehabilitation. 2014; 24(3) 1-9.
Chang-Hoon Woo, Yong Eun Lee, Seong-Soo Roh, Jae Soo Kim. Acupuncture Effects of Fatty Mice Induced by High Fat Diet. 2014; 24(3), 1-9.
Chang-Hoon Woo, Yong Eun Lee, Seong-Soo Roh and Jae Soo Kim. "Acupuncture Effects of Fatty Mice Induced by High Fat Diet" Journal of Korean Medicine Rehabilitation 24, no.3 (2014) : 1-9.
