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@article{ART002101598},
author={예성애 and 김호준 and KO SEONG-GYU and SONG YUN KYUNG},
title={Influence of Galgeun-tang on Gene Expression in Diet-Induced Obese Mice},
journal={Journal of Korean Medicine Rehabilitation},
issn={1229-1854},
year={2016},
volume={26},
number={2},
pages={1-12}

TY - JOUR
AU - 예성애
AU - 김호준
AU - KO SEONG-GYU
AU - SONG YUN KYUNG
TI - Influence of Galgeun-tang on Gene Expression in Diet-Induced Obese Mice
JO - Journal of Korean Medicine Rehabilitation
PY - 2016
VL - 26
IS - 2
PB - The Korean Academy Of Oriental Rehabilitation Medicine
SP - 1
EP - 12
SN - 1229-1854
AB - ObjectivesThe purpose of this study was to evaluate anti-obesity effect of Galgeun- tang (gegentang) and elucidate the effect of it on gene expression related to obesity.MethodsThe experiments were performed with the use of Diet-Induced Obese mice. They were grouped NC (normal control), HFD (high fat diet control), GGT (Galgeun-tang (gegentang), 700 mg/kg), ORL (Orlistat, 10 mg/kg). GGT was orally administered for 12 weeks. Body weight was measured every week. Real-time PCR was performed to inves-tigate the effect of GGT on gene expression in liver tissue.ResultsGGT group and ORL group were reduced in body weight compared with HFD. HFD increased PPARγ, SREBP-1, Leptin, aP2, FATP1, FAS gene expression compared with NC. GGT increased FATP1 gene expression. But GGT reduced PPARγ & FAS gene expression in liver tissue of diet-induced obese mice compared with HFD. ConclusionsThese results suggest that GGT is supposed to have a certain impact on the treatment of obesity. But more study is needed in the future. (J Korean Med Rehab 2016;26(2):1-12)
KW - Galgeun-tang (gegentang);obesity;orlistat Galgeun;Mahwang;Obesity- related genes
DO -
UR -
ER -

예성애, 김호준, KO SEONG-GYU and SONG YUN KYUNG. (2016). Influence of Galgeun-tang on Gene Expression in Diet-Induced Obese Mice. Journal of Korean Medicine Rehabilitation, 26(2), 1-12.

예성애, 김호준, KO SEONG-GYU and SONG YUN KYUNG. 2016, "Influence of Galgeun-tang on Gene Expression in Diet-Induced Obese Mice", Journal of Korean Medicine Rehabilitation, vol.26, no.2 pp.1-12.

예성애, 김호준, KO SEONG-GYU, SONG YUN KYUNG "Influence of Galgeun-tang on Gene Expression in Diet-Induced Obese Mice" Journal of Korean Medicine Rehabilitation 26.2 pp.1-12 (2016) : 1.

예성애, 김호준, KO SEONG-GYU, SONG YUN KYUNG. Influence of Galgeun-tang on Gene Expression in Diet-Induced Obese Mice. 2016; 26(2), 1-12.

예성애, 김호준, KO SEONG-GYU and SONG YUN KYUNG. "Influence of Galgeun-tang on Gene Expression in Diet-Induced Obese Mice" Journal of Korean Medicine Rehabilitation 26, no.2 (2016) : 1-12.

예성애; 김호준; KO SEONG-GYU; SONG YUN KYUNG. Influence of Galgeun-tang on Gene Expression in Diet-Induced Obese Mice. Journal of Korean Medicine Rehabilitation, 26(2), 1-12.

예성애; 김호준; KO SEONG-GYU; SONG YUN KYUNG. Influence of Galgeun-tang on Gene Expression in Diet-Induced Obese Mice. Journal of Korean Medicine Rehabilitation. 2016; 26(2) 1-12.

예성애, 김호준, KO SEONG-GYU, SONG YUN KYUNG. Influence of Galgeun-tang on Gene Expression in Diet-Induced Obese Mice. 2016; 26(2), 1-12.

예성애, 김호준, KO SEONG-GYU and SONG YUN KYUNG. "Influence of Galgeun-tang on Gene Expression in Diet-Induced Obese Mice" Journal of Korean Medicine Rehabilitation 26, no.2 (2016) : 1-12.