@article{ART002157945},
author={Ho-Jeong Do and 신예슬 and 이재환 and 안용준 and In-Hyuk Ha and Yoon-Jae Lee and 김미령 and 고원일 and 송설희 and 정화진 and Lee In Hee and 이재웅 and 김은지 and 김민정},
title={Stability of Danggwisu-san (Dangguixu-san) Water Extract, a Herbal Medicine, Under Various Storage Conditions},
journal={Journal of Korean Medicine Rehabilitation},
issn={1229-1854},
year={2016},
volume={26},
number={4},
pages={1-8}
TY - JOUR
AU - Ho-Jeong Do
AU - 신예슬
AU - 이재환
AU - 안용준
AU - In-Hyuk Ha
AU - Yoon-Jae Lee
AU - 김미령
AU - 고원일
AU - 송설희
AU - 정화진
AU - Lee In Hee
AU - 이재웅
AU - 김은지
AU - 김민정
TI - Stability of Danggwisu-san (Dangguixu-san) Water Extract, a Herbal Medicine, Under Various Storage Conditions
JO - Journal of Korean Medicine Rehabilitation
PY - 2016
VL - 26
IS - 4
PB - The Korean Academy Of Oriental Rehabilitation Medicine
SP - 1
EP - 8
SN - 1229-1854
AB - ObjectivesDanggwisu-san (Dangguixu-san) is a herbal prescription frequently used to treat pain or swelling caused by contusion. To determine the expiration period through sci-entific methodology, stability of Danggwisu-san (Dangguixu-san) water extract, a herbal medicine, was examined under various storage conditions and periods.MethodsDanggwisu-san (Dangguixu-san) was stored either at room temperature (23±2oC), under a refrigerating condition (4oC) or under a freezing condition (−18±2oC) for 0, 1, 2, 3 or 4 weeks and then freeze-dried. Total phenol and total flavonoid amounts were in-vestigated; contents of amygdalin (Prunus persica), paeoniflorin (Paeonia lactiflora), and gly-cyrrhizin (Glycyrrhiza uralensis) - the marker compounds of Danggwisu-san (Dangguixu-san) - were also analyzed through high performance liquid chromatography (HPLC).ResultsNo significant change in total phenol and total flavonoid amounts was observed under the indicated storage conditions. Moreover, the contents of marker compounds, i.e. amygdalin, paeoniflorin, and glycyrrhizin, did not alter significantly under the indicated con-ditions, as well.ConclusionsDanggwisu-san (Dangguixu-san) was found to be stable up until 4 weeks under the indicated conditions. Further studies on efficacy and long-term stability are war-ranted to establish the expiration period of Danggwisu-san (Dangguixu-san). (J Korean Med Rehabil 2016;26(4):1-8)
KW - Danggwisu-san (Dangguixu-san);Stability;Preservation;Anti-oxidation;High performance liquid chromatography
DO -
UR -
ER -
Ho-Jeong Do, 신예슬, 이재환, 안용준, In-Hyuk Ha, Yoon-Jae Lee, 김미령, 고원일, 송설희, 정화진, Lee In Hee, 이재웅, 김은지 and 김민정. (2016). Stability of Danggwisu-san (Dangguixu-san) Water Extract, a Herbal Medicine, Under Various Storage Conditions. Journal of Korean Medicine Rehabilitation, 26(4), 1-8.
Ho-Jeong Do, 신예슬, 이재환, 안용준, In-Hyuk Ha, Yoon-Jae Lee, 김미령, 고원일, 송설희, 정화진, Lee In Hee, 이재웅, 김은지 and 김민정. 2016, "Stability of Danggwisu-san (Dangguixu-san) Water Extract, a Herbal Medicine, Under Various Storage Conditions", Journal of Korean Medicine Rehabilitation, vol.26, no.4 pp.1-8.
Ho-Jeong Do, 신예슬, 이재환, 안용준, In-Hyuk Ha, Yoon-Jae Lee, 김미령, 고원일, 송설희, 정화진, Lee In Hee, 이재웅, 김은지, 김민정 "Stability of Danggwisu-san (Dangguixu-san) Water Extract, a Herbal Medicine, Under Various Storage Conditions" Journal of Korean Medicine Rehabilitation 26.4 pp.1-8 (2016) : 1.
Ho-Jeong Do, 신예슬, 이재환, 안용준, In-Hyuk Ha, Yoon-Jae Lee, 김미령, 고원일, 송설희, 정화진, Lee In Hee, 이재웅, 김은지, 김민정. Stability of Danggwisu-san (Dangguixu-san) Water Extract, a Herbal Medicine, Under Various Storage Conditions. 2016; 26(4), 1-8.
Ho-Jeong Do, 신예슬, 이재환, 안용준, In-Hyuk Ha, Yoon-Jae Lee, 김미령, 고원일, 송설희, 정화진, Lee In Hee, 이재웅, 김은지 and 김민정. "Stability of Danggwisu-san (Dangguixu-san) Water Extract, a Herbal Medicine, Under Various Storage Conditions" Journal of Korean Medicine Rehabilitation 26, no.4 (2016) : 1-8.
Ho-Jeong Do; 신예슬; 이재환; 안용준; In-Hyuk Ha; Yoon-Jae Lee; 김미령; 고원일; 송설희; 정화진; Lee In Hee; 이재웅; 김은지; 김민정. Stability of Danggwisu-san (Dangguixu-san) Water Extract, a Herbal Medicine, Under Various Storage Conditions. Journal of Korean Medicine Rehabilitation, 26(4), 1-8.
Ho-Jeong Do; 신예슬; 이재환; 안용준; In-Hyuk Ha; Yoon-Jae Lee; 김미령; 고원일; 송설희; 정화진; Lee In Hee; 이재웅; 김은지; 김민정. Stability of Danggwisu-san (Dangguixu-san) Water Extract, a Herbal Medicine, Under Various Storage Conditions. Journal of Korean Medicine Rehabilitation. 2016; 26(4) 1-8.
Ho-Jeong Do, 신예슬, 이재환, 안용준, In-Hyuk Ha, Yoon-Jae Lee, 김미령, 고원일, 송설희, 정화진, Lee In Hee, 이재웅, 김은지, 김민정. Stability of Danggwisu-san (Dangguixu-san) Water Extract, a Herbal Medicine, Under Various Storage Conditions. 2016; 26(4), 1-8.
Ho-Jeong Do, 신예슬, 이재환, 안용준, In-Hyuk Ha, Yoon-Jae Lee, 김미령, 고원일, 송설희, 정화진, Lee In Hee, 이재웅, 김은지 and 김민정. "Stability of Danggwisu-san (Dangguixu-san) Water Extract, a Herbal Medicine, Under Various Storage Conditions" Journal of Korean Medicine Rehabilitation 26, no.4 (2016) : 1-8.